Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jessica Filtjens"'
Autor:
Bert Malengier-Devlies, Jessica Filtjens, Kourosh Ahmadzadeh, Bram Boeckx, Jessica Vandenhaute, Amber De Visscher, Eline Bernaerts, Tania Mitera, Cato Jacobs, Lore Vanderbeke, Pierre Van Mol, Yannick Van Herck, Greet Hermans, Philippe Meersseman, Alexander Wilmer, Mieke Gouwy, Abhishek D. Garg, Stephanie Humblet-Baron, Frederik De Smet, Kimberly Martinod, Els Wauters, Paul Proost, Carine Wouters, Georges Leclercq, Diether Lambrechts, Joost Wauters, Patrick Matthys
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 is characterised by a broad spectrum of clinical and pathological features. Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we analysed the phenotype and activity of NK cells in the bloo
Externí odkaz:
https://doaj.org/article/13d4db38766a497bbdb3b0ba63a9215a
Autor:
Jessica Filtjens, Anais Roger, Linda Quatrini, Elisabeth Wieduwild, Jordi Gouilly, Guillaume Hoeffel, Rafaëlle Rossignol, Clara Daher, Guilhaume Debroas, Sandrine Henri, Claerwen M. Jones, Bernard Malissen, Laura K. Mackay, Aziz Moqrich, Francis R. Carbone, Sophie Ugolini
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Herpes simplex virus 1 (HSV-1) is a neurotropic virus that often cause pain via the induction of ulcer or blisters. Here the authors show, in mouse models of HSV-1 infection, that the pain-perceiving nociceptor Nav1.8 + neurons contribute to regulati
Externí odkaz:
https://doaj.org/article/42a3ec0604df491d8f51a1b9be9121c7
Autor:
Mathijs Willemsen, John S. Barber, Erika Van Nieuwenhove, Frederik Staels, Margaux Gerbaux, Julika Neumann, Teresa Prezzemolo, Emanuela Pasciuto, Vasiliki Lagou, Nancy Boeckx, Jessica Filtjens, Amber De Visscher, Patrick Matthys, Rik Schrijvers, Thomas Tousseyn, Mark O’Driscoll, Giorgia Bucciol, Susan Schlenner, Isabelle Meyts, Stephanie Humblet-Baron, Adrian Liston
BACKGROUND: Severe congenital neutropenia presents with recurrent infections early in life as a result of arrested granulopoiesis. Multiple genetic defects are known to block granulocyte differentiation; however, a genetic cause remains unknown in ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b6b05840aac2c6efbcbe0bb25a5d87
https://lirias.kuleuven.be/handle/20.500.12942/715773
https://lirias.kuleuven.be/handle/20.500.12942/715773
Autor:
Aline Van Acker, Konrad Gronke, Aindrila Biswas, Liesbet Martens, Yvan Saeys, Jessica Filtjens, Sylvie Taveirne, Els Van Ammel, Tessa Kerre, Patrick Matthys, Tom Taghon, Bart Vandekerckhove, Jean Plum, Ildiko Rita Dunay, Andreas Diefenbach, Georges Leclercq
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1431-1443 (2017)
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal Vγ3 T cells, intestinal intraepithelial CD8αα+ T lymphocytes, and CD49a+ liver natural killer (NK) cells. As the latter have recently been shown to
Externí odkaz:
https://doaj.org/article/6a4642d7f77f4b7b9316846659e527b8
Autor:
Bert Malengier‐Devlies, Eline Bernaerts, Kourosh Ahmadzadeh, Jessica Filtjens, Jessica Vandenhaute, Bram Boeckx, Oliver Burton, Amber De Visscher, Tania Mitera, Nele Berghmans, Geert Verbeke, Adrian Liston, Diether Lambrechts, Paul Proost, Carine Wouters, Patrick Matthys
Publikováno v:
Arthritis & Rheumatology. 74:1257-1270
Systemic juvenile idiopathic arthritis (JIA) is a systemic inflammatory disease with childhood onset. Systemic JIA is associated with neutrophilia, including immature granulocytes, potentially driven by the growth factor granulocyte-colony stimulatin
Autor:
Jessica Filtjens, Nicolas Coltel, Sabrina Cencig, Sylvie Taveirne, Els Van Ammel, Aline Van Acker, Tessa Kerre, Patrick Matthys, Tom Taghon, Bart Vandekerckhove, Yves Carlier, Carine Truyens, Georges Leclercq
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
The protozoan parasite Trypanosoma cruzi (T. cruzi) circulates in the blood upon infection and invades a variety of cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood duri
Externí odkaz:
https://doaj.org/article/2a6f8fca3b524acbb53ea20694bc609c
Autor:
Aline Van Acker, Jessica Filtjens, Sophie Van Welden, Sylvie Taveirne, Els Van Ammel, Mandy Vanhees, Lindsey Devisscher, Tessa Kerre, Tom Taghon, Bart Vandekerckhove, Jean Plum, Georges Leclercq
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110015 (2014)
The Ly49E NK receptor is a unique inhibitory receptor, presenting with a high degree of conservation among mouse strains and expression on both NK cells and intraepithelial-localised T cells. Amongst intraepithelial-localised T cells, the Ly49E recep
Externí odkaz:
https://doaj.org/article/e75211aa5e86425abb2c106e4099dced
Autor:
Jessica Filtjens, Lander Foquet, Sylvie Taveirne, Els Van Ammel, Mandy Vanhees, Aline Van Acker, Tessa Kerre, Tom Taghon, Bart Vandekerckhove, Jean Plum, Philippe E Van den Steen, Georges Leclercq
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87463 (2014)
Natural killer (NK) cells have different roles in the host response against Plasmodium-induced malaria depending on the stage of infection. Liver NK cells have a protective role during the initial hepatic stage of infection by production of the TH1-t
Externí odkaz:
https://doaj.org/article/cf14b117e1c04dbd926364f727e288e2
Autor:
Georges Leclercq, Louis Boon, Kourosh Ahmadzadeh, Jessica Vandenhaute, Jessica Filtjens, Anneleen Avau, Nathalie Van den Berghe, Tania Mitera, Maya Imbrechts, Bert Malengier-Devlies, Carine Wouters, Patrick Matthys
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 203(12)
Mice deficient in IFN-γ (IFN-γ knockout [KO] mice) develop a systemic inflammatory syndrome in response to CFA, in contrast to CFA-challenged wild-type (WT) mice who only develop a mild inflammation. Symptoms in CFA-challenged IFN-γ KO resemble sy
Autor:
Sylvie Taveirne, Tessa Kerre, Els Van Ammel, Els Louagie, Aline Van Acker, Jean Plum, Tom Taghon, Dirk Elewaut, Bart Vandekerckhove, Georges Leclercq, Jessica Filtjens
Publikováno v:
Cancer Immunology, Immunotherapy. 65:1365-1375
Ly49E is a member of the Ly49 family of NK receptors and is distinct from other members of this family on the basis of its structural properties, expression pattern and ligand recognition. Importantly, Ly49E receptor expression is high on small intes