Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jessica Elizabeth Reed"'
Autor:
Patricia J. Harvey, Gonzales Andrea, Shannon Leigh Black, Jeff B. Smaill, Ken Hook, Florence O. McCarthy, Stephen Fakhoury, Adrian Blaser, Haile Tecle, Freddy Rivault, Tong Zhu, Brian D. Palmer, Kevin Matthew Schlosser, Jessica Elizabeth Reed, Karen Elaine Sexton, William A. Denny, Irene W. Althaus, R. Thomas Winters, Teresa Ellis, Helen Tsenwhei Lee, Andrew M. Thompson, Erin Trachet, Alexander James Bridges, Julie Ann Spicer, Paul A. Ellis
Publikováno v:
Journal of Medicinal Chemistry. 59:8103-8124
Structure-activity relationships for inhibition of erbB1, erbB2, and erbB4 were determined for a series of quinazoline- and pyrido[3,4-d]pyrimidine-based analogues of the irreversible pan-erbB inhibitor, canertinib. Cyclic amine bearing crotonamides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e41b02b5002130f3f1a0856c03fbdf
https://doi.org/10.1021/acs.jmedchem.6b00883
https://doi.org/10.1021/acs.jmedchem.6b00883
Autor:
Alexander James Bridges, Rasmy Talaat, William F. Pool, Kan He, Michael D. Reily, Thomas F. Woolf, Jessica Elizabeth Reed
Publikováno v:
Drug Metabolism and Disposition. 32:639-646
Troglitazone (TGZ), the first glitazone used for the treatment of type II diabetes mellitus and removed from the market for liver toxicity, was shown to bind covalently to microsomal protein and glutathione (GSH) following activation by cytochrome P4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f4a079abf9fbd92b15e833a93ad2bd
https://doi.org/10.1124/dmd.32.6.639
https://doi.org/10.1124/dmd.32.6.639
Autor:
Jessica Elizabeth Reed, Karen Elaine Sexton, Alexei P. Krasutsky, Harriet W. Hamilton, Kevin Matthew Schlosser
Publikováno v:
ChemInform. 35
A highly efficient one-pot procedure for 3-sulfenylation of 2-carboxyindoles is described. Treatment of thiols with N-chlorosuccinimide at -78 degrees C in CH(2)Cl(2) affords sulfenyl chlorides in situ that readily react with 2-carboxyindoles to give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a9a50a6fcd511584f9a61600126df8
https://doi.org/10.1002/chin.200427107
https://doi.org/10.1002/chin.200427107