Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jessica E. Tanis"'
Autor:
Michael Clupper, Rachael Gill, Malek Elsayyid, Denis Touroutine, Jeffrey L. Caplan, Jessica E. Tanis
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105262- (2022)
Summary: Extracellular vesicles (EVs) are bioactive lipid-bilayer enclosed particles released from nearly all cells. One specialized site for EV shedding is the primary cilium. Here, we discover the conserved ion channel CLHM-1 as a ciliary EV cargo.
Externí odkaz:
https://doaj.org/article/d73d3818355e4fdb91a49af1cbe0d216
Publikováno v:
Cell Reports, Vol 36, Iss 13, Pp 109753- (2021)
Summary: Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no effective treatment. Diet, as a modifiable risk factor for AD, could potentially be targeted to slow disease onset and progression. However, complexity of the hum
Externí odkaz:
https://doaj.org/article/2c1655510b96446d8592285be3180d09
Autor:
Horia Vais, Karthik Mallilankaraman, Don-On Daniel Mak, Henry Hoff, Riley Payne, Jessica E. Tanis, J. Kevin Foskett
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 403-410 (2016)
The mitochondrial uniporter (MCU) is an ion channel that mediates Ca2+ uptake into the matrix to regulate metabolism, cell death, and cytoplasmic Ca2+ signaling. Matrix Ca2+ concentration is similar to that in cytoplasm, despite an enormous driving f
Externí odkaz:
https://doaj.org/article/8734499e717c4d678ba27e2910d8ed3c
Publikováno v:
Biology Open, Vol 2, Iss 11, Pp 1245-1252 (2013)
Summary Dysferlin is a member of the evolutionarily conserved ferlin gene family. Mutations in Dysferlin lead to Limb Girdle Muscular Dystrophy 2B (LGMD2B), an inherited, progressive and incurable muscle disorder. However, the molecular mechanisms un
Externí odkaz:
https://doaj.org/article/6ef88cb4ff624a2495946a6051c6699f
Autor:
Allison N, Davis, Jessica E, Tanis
Publikováno v:
Journal of visualized experiments : JoVE. (184)
At the neuromuscular junction (NMJ), the binding of the excitatory neurotransmitter acetylcholine (ACh) to postsynaptic receptors leads to muscle contraction. As in vertebrate skeletal muscle, cholinergic signaling in the body wall muscles of the mod
Autor:
Jessica E. Tanis, Allison N. Davis
Publikováno v:
Journal of Visualized Experiments.
Autor:
Kevin M Collins, Addys Bode, Robert W Fernandez, Jessica E Tanis, Jacob C Brewer, Matthew S Creamer, Michael R Koelle
Publikováno v:
eLife, Vol 5 (2016)
Like many behaviors, Caenorhabditis elegans egg laying alternates between inactive and active states. To understand how the underlying neural circuit turns the behavior on and off, we optically recorded circuit activity in behaving animals while mani
Externí odkaz:
https://doaj.org/article/ebe22fcff2cc4706943a6e372af82db4
A Rapid, SuperSelective Method for Detection of Single Nucleotide Variants in Caenorhabditis elegans
Autor:
Jessica E. Tanis, Denis Touroutine
Publikováno v:
Genetics
With the widespread use of single nucleotide variants generated through mutagenesis screens and genome editing technologies, there is pressing need for an efficient and low-cost strategy to genotype single nucleotide substitutions. We have developed
Autor:
Michael Clupper, Rachael Gill, Malek Elsayyid, Denis Touroutine, Jeffrey Caplan, Jessica E. Tanis
Publikováno v:
SSRN Electronic Journal.
Autor:
Michael Clupper, Rachael Gill, Malek Elsayyid, Denis Touroutine, Jeffrey L. Caplan, Jessica E. Tanis
SUMMARYExtracellular vesicles (EVs) are bioactive lipid-bilayer enclosed particles released from nearly all cells. One specialized site for EV shedding is the primary cilium, a conserved signaling organelle. The mechanisms underlying cargo enrichment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c62d07a96d7e44b9124f02775b6452
https://doi.org/10.1101/2021.12.19.473369
https://doi.org/10.1101/2021.12.19.473369