Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jessica E. Lisle"'
Autor:
Adriana C. Pliego Zamora, Hansini Ranasinghe, Jessica E. Lisle, Chun Ki Ng, Stephen Huang, Racheal Wadlow, Andrew M. Scott, Andrew W. Boyd, Christopher I. Slape
Publikováno v:
Cancers, Vol 13, Iss 15, p 3858 (2021)
We recently characterised the NUP98-HOXD13 (NHD13) mouse as a model of T-cell pre-leukaemia, featuring thymocytes that can engraft in recipient animals and progress to T-cell acute lymphoblastic leukaemia (T-ALL). However, loss of this engraftment ab
Externí odkaz:
https://doaj.org/article/51f29d90d7984faca589257edbacc472
Autor:
Adrian C. Herington, Jessica E. Lisle, Carson R. Stephens, Sally-Anne Stephenson, Scott H. Stansfield, Inga Mertens-Walker, Judith A. Clements
Publikováno v:
Experimental Cell Research. 333:136-146
BackgroundEphrin-B2 is the sole physiologically-relevant ligand of the receptor tyrosine kinase EphB4, which is over-expressed in many epithelial cancers, including 66% of prostate cancers, and contributes to cancer cell survival, invasion and migrat
Autor:
John D. Hooper, Judith A. Clements, Brittney S. Harrington, Andreas Wortmann, Mark N. Adams, Sally-Anne Stephenson, Ying Dong, Jessica E. Lisle, Adrian C. Herington
Publikováno v:
Biological Chemistry. 395:977-990
The 15 members of the kallikrein-related serine peptidase (KLK) family have diverse tissue-specific expression profiles and roles in a range of cellular processes, including proliferation, migration, invasion, differentiation, inflammation and angiog
Autor:
Jessica E. Lisle, Adriana Pliego Zamora, Stephen Huang, Christopher Slape, Hansini Ranasinghe
Publikováno v:
Experimental Hematology. 76:S82
Current therapies for T cell acute lymphoblastic leukaemia (T-ALL) have achieved relatively successful results. However, relapse cases are often fatal. Relapse is caused by the presence of leukemic stem cells that are resistant to treatment. Using th
Publikováno v:
Experimental Hematology. 76:S85
EphA3, a receptor tyrosine kinase which mediates cell-cell interactions, is a potential therapeutic target for haematopoietic malignancies because of overexpression of EphA3 in patients with these diseases, along with negligible expression in healthy
Autor:
Christopher Slape, Jessica E. Lisle, Johnny X. Huang, Liang Zhao, Peter Koopman, Adriana Pliego Zamora
Publikováno v:
Experimental Hematology. 64:S104
Publikováno v:
Experimental Hematology. 64:S104
Autor:
Jessica E. Lisle, Mohanan S N Maharaj, Adrian C. Herington, Inga Mertens-Walker, Sally-Anne Stephenson
Publikováno v:
Growth factors (Chur, Switzerland). 32(6)
Several Eph receptor tyrosine kinases (RTKs) are commonly over-expressed in epithelial and mesenchymal cancers and are recognized as promising therapeutic targets. Although normal interaction between Eph receptors and their ephrin ligands stimulates
Autor:
Adrian C. Herington, William A. Nyberg, Jessica E. Lisle, Carson R. Stephens, Raphael Rutkowski, Sally-Anne Stephenson, Leslie Burke, Inga Mertens-Walker
Publikováno v:
Experimental cell research. 333(1)
The EphB4 receptor tyrosine kinase is over-expressed in a variety of different epithelial cancers including prostate where it has been shown to be involved in survival, migration and angiogenesis. We report here that EphB4 also resides in the nucleus
Autor:
Jessica E. Lisle, Sally-Anne Stephenson, Inga Mertens-Walker, Adrian C. Herington, Raphael Rutkowski
Publikováno v:
Biochimica et biophysica acta. 1835(2)
Although at present, there is a high incidence of prostate cancer, particularly in the Western world, mortality from this disease is declining and occurs primarily only from clinically significant late stage tumors with a poor prognosis. A major curr