Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jessica E. Boles"'
Publikováno v:
Molecules, Vol 25, Iss 18, p 4126 (2020)
Herein, we present a series of supramolecular self-associating amphiphilic (SSA) salts and establish the potential for these molecular constructs to act as next-generation solution-state molecular delivery vehicles. We characterise the self-associati
Externí odkaz:
https://doaj.org/article/cd5316fce3b9408fb167c85127819574
Autor:
Kylie Yang, Jessica E. Boles, Lisa J. White, Kira L. F. Hilton, Hin Yuk Lai, Yifan Long, Jennifer R. Hiscock, Cally J. E. Haynes
Publikováno v:
RSC Advances. 12:27877-27880
Synthetic ionophores are promising therapeutic targets, yet poor water solubility limits their potential for translation into the clinic. Here we report a water-soluble, supramolecular self-associating amphiphile that functions as a cation uniporter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c62a5f7a01c587f6b7b11c54257811e
https://doi.org/10.1039/d2ra05314d
https://doi.org/10.1039/d2ra05314d
Autor:
Andzelika Rutkauskaite, Lisa J. White, Jessica E. Boles, Kira L. F. Hilton, Melanie Clifford, Bethany Patenall, Bree R. Streather, Daniel P. Mulvihill, Samantha A. Henry, Mark Shepherd, J. Mark Sutton, Charlotte K. Hind, Jennifer R. Hiscock
Publikováno v:
Supramolecular Chemistry. 33:677-686
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87724bb06697eb59a320f91985a516b2
https://doi.org/10.1080/10610278.2022.2161902
https://doi.org/10.1080/10610278.2022.2161902
Autor:
Jessica E. Boles, Charlotte Bennett, Jennifer Baker, Kira L. F. Hilton, Hiral A. Kotak, Ewan R. Clark, Yifan Long, Lisa J. White, Hin Yuk Lai, Charlotte K. Hind, J. Mark Sutton, Michelle D. Garrett, Anne Cheasty, Jose L. Ortega-Roldan, Mark Charles, Cally J. E. Haynes, Jennifer R. Hiscock
The rise of antimicrobial resistance remains one of the greatest global health threats facing humanity. Furthermore, the development of novel antibiotics has all but ground to a halt due to a collision of intersectional pressures. Herein we determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21e6bf211f33a882a85a150f6c66f7d
Publikováno v:
RSC Advances
Supramolecular self-associating amphiphiles (SSAs) are a class of amphiphilic salt which have demonstrated antimicrobial activity against both Gram-positive and Gram-negative bacteria. Herein, we show that SSAs are also able to increase the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f519e306e36a01a05cb76f3a823eeaa
https://doi.org/10.1039/d1ra00998b
https://doi.org/10.1039/d1ra00998b
Autor:
Nova O. Dora, George T. Williams, Daniel P. Mulvihill, Jack A. Doolan, Edith Blackburn, Jennifer R. Hiscock, Scarlett E. G. Turner, Trevor Askwith, Lisa J. White, J. Daniel Hothersall, Michelle D. Garrett, Jessica E. Boles
Publikováno v:
RSC Advances. 11:14213-14217
Many chemotherapeutic drugs have a narrow therapeutic window due to inefficient tumour cell permeation. Supramolecular self-associating amphiphilic salts (SSAs) are a unique class of small molecules that offer potential as next generation cancer drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f968cb81d726bf66b8544a191a3d0e5
https://doi.org/10.1039/d1ra02281d
https://doi.org/10.1039/d1ra02281d
Autor:
Rebecca J. Ellaby, Helena J. Shepherd, Ben Wilson, George T. Williams, Daniel P. Mulvihill, Jessica E. Boles, Jennifer R. Hiscock, Dominique Chu, Kendrick K. L. Ng, Laura R. Blackholly, Lisa J. White, Nyasha Allen
Publikováno v:
Chemmedchem
Herein we report 50 structurally related supramolecular self‐associating amphiphilic (SSA) salts and related compounds. These SSAs are shown to act as antimicrobial agents, active against model Gram‐positive (methicillin‐resistant Staphylococcu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41ed2c6521a91661c2947a3b58bc32d
https://doi.org/10.1002/cmdc.202000533
https://doi.org/10.1002/cmdc.202000533
Autor:
George T. Williams, Kira L. F. Hilton, Laura R. Blackholly, Lisa J. White, Charlotte K. Hind, Luke S. Alesbrook, Daniel P. Mulvihill, J. Mark Sutton, Jessica E. Boles, Jennifer R. Hiscock, Rebecca J. Ellaby, Nyasha Allen
Publikováno v:
Journal of Materials Chemistry B. 8:4694-4700
SSAs are a class of supramolecular self-associating amphiphilic salt, the anionic component of which contains a covalently bound hydrogen bond donor-acceptor motif. This results in a monomeric unit which can adopt multiple hydrogen bonding modes simu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f92bb311918d7db59cfa9597d7c68f8
https://doi.org/10.1039/d0tb00875c
https://doi.org/10.1039/d0tb00875c
Autor:
Jennifer R. Hiscock, Kira L. F. Hilton, Charlotte K. Hind, Daniel P. Mulvihill, Jessica E. Boles, Rebecca J. Ellaby, Melanie Clifford, Bethany L. Patenall, Lisa J. White, Kendrick K. L. Ng
Herein, we report a series of di-anionic supramolecular self-associating amphiphiles (SSAs). We elucidate the antimicrobial properties of these SSAs against both methicillin resistant Staphylococcus aureus and Escherichia coli. In addition, we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadcac3cc49995d34d75831d4c9d8c79
https://kar.kent.ac.uk/90985/17/d1cc05455d.pdf
https://kar.kent.ac.uk/90985/17/d1cc05455d.pdf
Publikováno v:
Molecules
Volume 25
Issue 18
Molecules, Vol 25, Iss 4126, p 4126 (2020)
Volume 25
Issue 18
Molecules, Vol 25, Iss 4126, p 4126 (2020)
Herein, we present a series of supramolecular self-associating amphiphilic (SSA) salts and establish the potential for these molecular constructs to act as next-generation solution-state molecular delivery vehicles. We characterise the self-associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0740d8a9d78c7ebbd7365572ec6c87d0
https://pubmed.ncbi.nlm.nih.gov/32917007
https://pubmed.ncbi.nlm.nih.gov/32917007