Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jessica E Tanis"'
Autor:
Michael Clupper, Rachael Gill, Malek Elsayyid, Denis Touroutine, Jeffrey L. Caplan, Jessica E. Tanis
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105262- (2022)
Summary: Extracellular vesicles (EVs) are bioactive lipid-bilayer enclosed particles released from nearly all cells. One specialized site for EV shedding is the primary cilium. Here, we discover the conserved ion channel CLHM-1 as a ciliary EV cargo.
Externí odkaz:
https://doaj.org/article/d73d3818355e4fdb91a49af1cbe0d216
Publikováno v:
Cell Reports, Vol 36, Iss 13, Pp 109753- (2021)
Summary: Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no effective treatment. Diet, as a modifiable risk factor for AD, could potentially be targeted to slow disease onset and progression. However, complexity of the hum
Externí odkaz:
https://doaj.org/article/2c1655510b96446d8592285be3180d09
Autor:
Timothy Chaya, Shrey Patel, Erin M Smith, Andy Lam, Elaine N Miller, Michael Clupper, Kirsten Kervin, Jessica E Tanis
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
AbstractAt the neuromuscular junction (NMJ), postsynaptic ionotropic acetylcholine receptors (AChRs) transduce a chemical signal released from a cholinergic motor neuron into an electrical signal to induce muscle contraction. To identify regulators o
Externí odkaz:
https://doaj.org/article/271c1155782e435e98f8f9332632fae1
Autor:
Horia Vais, Karthik Mallilankaraman, Don-On Daniel Mak, Henry Hoff, Riley Payne, Jessica E. Tanis, J. Kevin Foskett
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 403-410 (2016)
The mitochondrial uniporter (MCU) is an ion channel that mediates Ca2+ uptake into the matrix to regulate metabolism, cell death, and cytoplasmic Ca2+ signaling. Matrix Ca2+ concentration is similar to that in cytoplasm, despite an enormous driving f
Externí odkaz:
https://doaj.org/article/8734499e717c4d678ba27e2910d8ed3c
Autor:
Allison N, Davis, Jessica E, Tanis
Publikováno v:
Journal of visualized experiments : JoVE. (184)
At the neuromuscular junction (NMJ), the binding of the excitatory neurotransmitter acetylcholine (ACh) to postsynaptic receptors leads to muscle contraction. As in vertebrate skeletal muscle, cholinergic signaling in the body wall muscles of the mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f377621c6ba7519d965204f4fb09bf17
https://pubmed.ncbi.nlm.nih.gov/35758705
https://pubmed.ncbi.nlm.nih.gov/35758705
Autor:
Jessica E. Tanis, Allison N. Davis
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bc211864ba6e4bdf46477a2ee69dbc
https://doi.org/10.3791/64056-v
https://doi.org/10.3791/64056-v
Publikováno v:
Biology Open, Vol 2, Iss 11, Pp 1245-1252 (2013)
Summary Dysferlin is a member of the evolutionarily conserved ferlin gene family. Mutations in Dysferlin lead to Limb Girdle Muscular Dystrophy 2B (LGMD2B), an inherited, progressive and incurable muscle disorder. However, the molecular mechanisms un
Externí odkaz:
https://doaj.org/article/6ef88cb4ff624a2495946a6051c6699f
Autor:
Kevin M Collins, Addys Bode, Robert W Fernandez, Jessica E Tanis, Jacob C Brewer, Matthew S Creamer, Michael R Koelle
Publikováno v:
eLife, Vol 5 (2016)
Like many behaviors, Caenorhabditis elegans egg laying alternates between inactive and active states. To understand how the underlying neural circuit turns the behavior on and off, we optically recorded circuit activity in behaving animals while mani
Externí odkaz:
https://doaj.org/article/ebe22fcff2cc4706943a6e372af82db4
A Rapid, SuperSelective Method for Detection of Single Nucleotide Variants in Caenorhabditis elegans
Autor:
Jessica E. Tanis, Denis Touroutine
Publikováno v:
Genetics
With the widespread use of single nucleotide variants generated through mutagenesis screens and genome editing technologies, there is pressing need for an efficient and low-cost strategy to genotype single nucleotide substitutions. We have developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a093b282c301047204c4b70bdf9501
http://europepmc.org/articles/PMC7536863
http://europepmc.org/articles/PMC7536863
Autor:
Michael Clupper, Rachael Gill, Malek Elsayyid, Denis Touroutine, Jeffrey Caplan, Jessica E. Tanis
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc6bf921db43a9b7965125522ba53c52
https://doi.org/10.2139/ssrn.4020528
https://doi.org/10.2139/ssrn.4020528