Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jessica Doerner"'
Autor:
Antonia R. Bass, Marisa S. Egan, Jasmine Alexander-Floyd, Natasha Lopes Fischer, Jessica Doerner, Sunny Shin
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The inflammasome is essential for host defense against intracellular bacterial pathogens, including Legionella pneumophila, the causative agent of the severe pneumonia Legionnaires’ disease. Inflammasomes recruit and activate caspases, whi
Externí odkaz:
https://doaj.org/article/aaf626656445465281591767045e51d3
Autor:
Samantha A. Chalmers, Jing Wen, Jessica Doerner, Ariel Stock, Carla M. Cuda, Hadijat M. Makinde, Harris Perlman, Todd Bosanac, Deborah Webb, Gerald Nabozny, Jay S. Fine, Elliott Klein, Meera Ramanujam, Chaim Putterman
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects different end organs, including skin and brain. We and others have previously shown the importance of macrophages in the pathogenesis of cutaneous an
Externí odkaz:
https://doaj.org/article/6f0eb2318849441e9caef153ed2cf9da
Autor:
Jessica Doerner, Jing Wen, Deborah Webb, Samantha A. Chalmers, Elliott Klein, Gerald Nabozny, Ariel D. Stock, Meera Ramanujam, Todd Bosanac, Jay S. Fine, Hadijat M. Makinde, Chaim Putterman, Harris Perlman, Carla M. Cuda
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects different end organs, including skin and brain. We and others have previously shown the importance of macrophages in the pathogenesis of cutaneous and neurops
Autor:
Lars Aabakken, Jessica Doerner, Chaim Putterman, Kjetil Isaksen, Lars Normann Karlsen, Tore Grimstad, Roald Omdal, Inger Marie Skoie
Publikováno v:
Scandinavian Journal of Gastroenterology. 52:420-424
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) may be involved in the pathogenesis of inflammatory bowel disease. The aim was to investigate if TWEAK may reflect disease activity in inflammatory bowel disease.In this cohort study, 139 c
Autor:
Ariel D. Stock, Chaim Putterman, Christopher H. Chen, Maria Gulinello, Jing Wen, Jessica Doerner
Publikováno v:
Brain, Behavior, and Immunity. 54:27-37
Fn14, the sole known signaling receptor for the TNF family member TWEAK, is inducibly expressed in the central nervous system (CNS) in endothelial cells, astrocytes, microglia, and neurons. There is increasing recognition of the importance of the TWE
Autor:
Linda C. Burkly, Jing Wen, Aleksandra Deczkowska, Ariel D. Stock, Jennifer S. Michaelson, Yumin Xia, Kuti Baruch, Jessica Doerner, Michal Schwartz, Karen M. Weidenheim, Maria Gulinello, Chaim Putterman
Publikováno v:
Journal of Autoimmunity. 60:40-50
Neuropsychiatric disease is one of the most common manifestations of human systemic lupus erythematosus, but the mechanisms remain poorly understood. In human brain microvascular endothelial cells in vitro, TNF-like weak inducer of apoptosis (TWEAK)
Autor:
Dinesh Chandra, Mahantesh S. Navati, Joel M. Friedman, Adam J. Friedman, Jessica Doerner, Joshua D. Nosanchuk, Vitor Cabral, Aimee Krausz, Alicea Clendaniel, Stacey L. Harper, Rabab A. Charafeddine, Brandon L. Adler, Hongying Liang, Leslie Gunther
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 11:195-206
Burn wounds are often complicated by bacterial infection, contributing to morbidity and mortality. Agents commonly used to treat burn wound infection are limited by toxicity, incomplete microbial coverage, inadequate penetration, and rising resistanc
Autor:
Sebastien Monette, Mayu O. Frank, Nathalie E. Blachère, Margaret Herre, Emily Conn Gantman, Patricia K. Foo, Robert B. Darnell, Bianca D. Santomasso, John J. Fak, Jessica Doerner, Dana E. Orange
Publikováno v:
European Journal of Immunology. 44:3240-3251
Paraneoplastic neurologic diseases (PND) involving immune responses directed toward intracellular antigens are poorly understood. Here, we examine immunity to the PND antigen Nova2, which is expressed exclusively in central nervous system (CNS) neuro
Publikováno v:
Clinical immunology (Orlando, Fla.). 185
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease that can affect multiple end organs. Kidney and brain are two of the organs most commonly involved in SLE. Past studies have suggested the importance of macrophages in the path
Autor:
Christian Harcken, Meera Ramanujam, Sara Khalil, Leal Herlitz, Todd Bosanac, Janice Dimock, Elliott Klein, Samantha A. Chalmers, Jessica Doerner, Deborah Webb, Jay S. Fine, Elise Seccareccia, Chaim Putterman, Di Feng, Evan Der, Dustin Smith
Publikováno v:
Scientific Reports
Lupus nephritis (LN) is a potentially dangerous end organ pathology that affects upwards of 60% of SLE patients. Bruton’s tyrosine kinase (BTK) is important for B cell development, Fc receptor signaling, and macrophage polarization. In this study,