Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jessica Dantzer"'
Autor:
Todd C. Skaar, Cesar A. Santa-Maria, P Ouyang, RS Blumenthal, Norah Lynn Henry, Jessica Dantzer, W Post, D. Zeruesenay, DA Flockhart, Daniel F. Hayes, Steffi Oesterreich, Lang Li, Anna Maria Storniolo, Vered Stearns, James M. Rae, Anne T. Nguyen
Publikováno v:
Cancer Research. 73:P1-08
Background Aromatase inhibitors (AI) can exert unfavorable effects on lipid profiles, but previous studies have reported inconsistent results. Given the intricate biological relationship between estrogen and lipid profiles, these mixed results may be
Autor:
Jason D. Robarge, Daniel F. Hayes, Jessica Dantzer, Anna Maria Storniolo, Norah Lynn Henry, Renee W. Pinsky, James M. Rae, David A. Flockhart, Nagi F. Khouri, Lubomir M. Hadjiiski, Santosh Philips, Anne T. Nguyen, Mark A. Helvie, Zeruesenay Desta, Vered Stearns, Todd C. Skaar, Steffi Oesterreich, Chuan Zhou, Heang Ping Chan, Liang Li, Chirayu P. Goswami
Publikováno v:
British Journal of Cancer
Background: Change in breast density may predict outcome of women receiving adjuvant hormone therapy for breast cancer. We performed a prospective clinical trial to evaluate the impact of inherited variants in genes involved in oestrogen metabolism a
Autor:
C. An, Y. Zhao, Nancy Pech, Xiaoman Li, Mary C. Dinauer, Manuel Grez, S. Griffin, Mohammed A. Sadat, Sean D. Mooney, Mervin C. Yoder, S. Dirscherl, Scott Cross, Cecilia Barese, Kenneth Cornetta, L. Sastry, Jessica Dantzer, W. S. Goebel, Troy Hawkins, Attilio Orazi
Publikováno v:
Gene therapy
X-linked chronic granulomatous disease (X-CGD) is an inherited immunodeficiency with absent phagocyte NADPH-oxidase activity caused by defects in the gene-encoding gp91(phox). Here, we evaluated strategies for less intensive conditioning for gene the
Autor:
Predrag Radivojac, Jessica Dantzer, Randy Heiland, Sean D. Mooney, Peter H. Baenziger, Adebayo Olowoyeye, Arti Singh, Maricel G. Kann
Publikováno v:
Nucleic Acids Research
Understanding how genetic variation affects the molecular function of gene products is an emergent area of bioinformatic research. Here, we present updates to MutDB (http://www.mutdb.org), a tool aiming to aid bioinformatic studies by integrating pub
Autor:
Jessica Dantzer, Daniel F. Hayes, Santosh Philips, Thomas N. Hangartner, Vered Stearns, N. Lynn Henry, Kelley M. Kidwell, David A. Flockhart, Munro Peacock, Catherine Van Poznak, Zeruesenay Desta, Todd C. Skaar, Anne T. Nguyen, Steffi Oesterreich, Lang Li, Anna Maria Storniolo, James M. Rae
Publikováno v:
Breast cancer research and treatment. 154(2)
Adjuvant therapy for hormone receptor (HR) positive postmenopausal breast cancer patients includes aromatase inhibitors (AI). While both the non-steroidal AI letrozole and the steroidal AI exemestane decrease serum estrogen concentrations, there is e
Publikováno v:
Nucleic Acids Research
Non-synonymous single nucleotide polymorphisms (SNPs) and mutations have been associated with human phenotypes and disease. As more and more SNPs are mapped to phenotypes, understanding how these variations affect the function and expression of genes
Autor:
Kenneth Cornetta, Troy Hawkins, Keithanne Mockaitis, Sean D. Mooney, Brandon Peters, Jessica Dantzer, Mary C. Dinauer
Publikováno v:
Bioinformatics
Summary: Retroviral integration has been implicated in several biomedical applications, including identification of cancer-associated genes and malignant transformation in gene therapy clinical trials. We introduce an efficient and scalable method fo
Autor:
Janet S. Carpenter, Lang Li, Anna Maria Storniolo, Zeruesenay Desta, Todd C. Skaar, Christina L. Gersch, Jessica Dantzer, N. Lynn Henry, Daniel F. Hayes, Vered Stearns, Santosh Philips, Steffi Oesterreich, Anne T. Nguyen, James M. Rae, Kelley M. Kidwell, David A. Flockhart
Up to 25 % of patients discontinue adjuvant aromatase inhibitor (AI) therapy due to intolerable symptoms. Predictors of which patients will be unable to tolerate these medications have not been defined. We hypothesized that inherited variants in cand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c97a538cf6efc9196418dd7672d208
https://europepmc.org/articles/PMC3646626/
https://europepmc.org/articles/PMC3646626/
Autor:
Amalia S. Lehmann, Lang Li, Catherine L. McCormick, Scott J. Hebbring, Jeesun Jung, Kyle Beagle, Jessica Dantzer, Santosh Philips, David M. Haas, Todd C. Skaar
To determine the impact of maternal and fetal single nucleotide polymorphisms in key betamethasone pathways on neonatal outcomes.DNA was obtained from women given betamethasone and their infants. Samples were genotyped for 73 exploratory drug metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43aaf6f441aafed839664c89142f588f
https://europepmc.org/articles/PMC3340461/
https://europepmc.org/articles/PMC3340461/
Automated analysis of viral integration sites in gene therapy research using the SeqMap web resource
Autor:
Jessica Dantzer, Sara Dirscherl, Xiaoman Li, Jonathan Nowacki, Scott Cross, Sean D. Mooney, Kenneth Cornetta, Brandon Peters, Mary C. Dinauer
Publikováno v:
Gene therapy. 15(18)
Research in gene therapy involving genome-integrating vectors now often includes analysis of vector integration sites across the genome using methods such as ligation-mediated PCR (LM-PCR) or linear amplification-mediated PCR (LAM-PCR). To help resea