Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jessica D. Sun"'
Autor:
Sushil Kumar, Jessica D. Sun, Libo Zhang, Reza Bayat Mokhtari, Bing Wu, Fanying Meng, Qian Liu, Deepthi Bhupathi, Yan Wang, Herman Yeger, Charles Hart, Sylvain Baruchel
Publikováno v:
Translational Oncology, Vol 11, Iss 4, Pp 911-919 (2018)
Antiangiogenic therapy has shown promising results in preclinical and clinical trials. However, tumor cells acquire resistance to this therapy by gaining ability to survive and proliferate under hypoxia induced by antiangiogenic therapy. Combining an
Externí odkaz:
https://doaj.org/article/b8d0cf9939e1467aaede794a5eb26ac2
Autor:
Jean-François Geschwind, Charles P. Hart, Jessica D. Sun, MingDe Lin, Constantine Frangakis, Rüdiger E. Schernthaner, Julius Chapiro, Juvenal Reyes, Boris Gorodetski, Toby C. Cornish, Cory F. Brayton, Shanmugasundaram Ganapathy-Kanniappan, Vasily Pekurovsky, Sahar Mirpour, Rafael Duran
Supplementary Figure S1: Quantitative volumetric image analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddb6ea380d25867d75fa656f0733a28
https://doi.org/10.1158/1078-0432.22468979
https://doi.org/10.1158/1078-0432.22468979
Autor:
Philippe Lambin, Ludwig J. Dubois, Wouter van Elmpt, Albert D. Windhorst, Charles P. Hart, Jessica D. Sun, Ala Yaromina, Ruud G.P.M. van Stiphout, Natasja G. Lieuwes, Rianne Biemans, Catharina M.L. Zegers, Sarah G.J.A. Peeters
Purpose: Conventional anticancer treatments are often impaired by the presence of hypoxia. TH-302 selectively targets hypoxic tumor regions, where it is converted into a cytotoxic agent. This study assessed the efficacy of the combination treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6c12a383ebbb8357c013bcc54bfc2e
https://doi.org/10.1158/1078-0432.c.6523374
https://doi.org/10.1158/1078-0432.c.6523374
Autor:
Jean-François Geschwind, Charles P. Hart, Jessica D. Sun, MingDe Lin, Constantine Frangakis, Rüdiger E. Schernthaner, Julius Chapiro, Juvenal Reyes, Boris Gorodetski, Toby C. Cornish, Cory F. Brayton, Shanmugasundaram Ganapathy-Kanniappan, Vasily Pekurovsky, Sahar Mirpour, Rafael Duran
Supplementary Figure S1-S3 legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b8504a92fab277f37049d541fe11cb
https://doi.org/10.1158/1078-0432.22468976
https://doi.org/10.1158/1078-0432.22468976
Autor:
Jean-François Geschwind, Charles P. Hart, Jessica D. Sun, MingDe Lin, Constantine Frangakis, Rüdiger E. Schernthaner, Julius Chapiro, Juvenal Reyes, Boris Gorodetski, Toby C. Cornish, Cory F. Brayton, Shanmugasundaram Ganapathy-Kanniappan, Vasily Pekurovsky, Sahar Mirpour, Rafael Duran
Purpose: To evaluate safety and characterize anticancer efficacy of hepatic hypoxia-activated intra-arterial therapy (HAIAT) with evofosfamide in a rabbit model.Experimental Design: VX2-tumor-bearing rabbits were assigned to 4 intra-arterial therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d7a3bc808e49d420e4788e885017e9
https://doi.org/10.1158/1078-0432.c.6527108.v1
https://doi.org/10.1158/1078-0432.c.6527108.v1
Autor:
Philippe Lambin, Ludwig J. Dubois, Wouter van Elmpt, Albert D. Windhorst, Charles P. Hart, Jessica D. Sun, Ala Yaromina, Ruud G.P.M. van Stiphout, Natasja G. Lieuwes, Rianne Biemans, Catharina M.L. Zegers, Sarah G.J.A. Peeters
Supplementary figure 4. Body weight was monitored during and after treatment for both rhabdomyosarcoma (A) and H460 (B) tumor-bearing animals. The change in body weight is represented in percentage. Data represent mean {plus minus} SEM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d6ede64f77ad23c884db9717093704
https://doi.org/10.1158/1078-0432.22456641
https://doi.org/10.1158/1078-0432.22456641
Autor:
Charles P. Hart, Mark D. Matteucci, John G. Curd, W. Steve Ammons, Jian-Xin Duan, Yan Wang, Damien Ferraro, Dharmendra Ahluwalia, Jingli Wang, Qian Liu, Jessica D. Sun
PDF file - 2.7MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fcaedba61d40db0e601de0a736eb65
https://doi.org/10.1158/1078-0432.22443263
https://doi.org/10.1158/1078-0432.22443263
Autor:
Philippe Lambin, Ludwig J. Dubois, Wouter van Elmpt, Albert D. Windhorst, Charles P. Hart, Jessica D. Sun, Ala Yaromina, Ruud G.P.M. van Stiphout, Natasja G. Lieuwes, Rianne Biemans, Catharina M.L. Zegers, Sarah G.J.A. Peeters
Supplementary Table 2. Time to reach 4 times start volume per treatment group for H460 bearing animals. Data represent mean {plus minus} SD, p-value and sensitization enhancement ratio.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f805bf8020ef756cd7e2b6ea21878d8
https://doi.org/10.1158/1078-0432.22456653
https://doi.org/10.1158/1078-0432.22456653
Autor:
Philippe Lambin, Ludwig J. Dubois, Wouter van Elmpt, Albert D. Windhorst, Charles P. Hart, Jessica D. Sun, Ala Yaromina, Ruud G.P.M. van Stiphout, Natasja G. Lieuwes, Rianne Biemans, Catharina M.L. Zegers, Sarah G.J.A. Peeters
Supplementary figure 3. A) Tumor growth of rhabdomyosarcoma bearing animals (n=8) treated with TH-302 (25mg/kg) in combination with 4, 8 or 12Gy of RT. Data represent mean {plus minus} SEM. B) T4xSV for rhabdomyosarcoma bearing animals treated with T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b95d59a446592830eaef4e18169e09b
https://doi.org/10.1158/1078-0432.22456644.v1
https://doi.org/10.1158/1078-0432.22456644.v1
Autor:
Philippe Lambin, Ludwig J. Dubois, Wouter van Elmpt, Albert D. Windhorst, Charles P. Hart, Jessica D. Sun, Ala Yaromina, Ruud G.P.M. van Stiphout, Natasja G. Lieuwes, Rianne Biemans, Catharina M.L. Zegers, Sarah G.J.A. Peeters
Supplementary figure 1. A) Treatment schedule for the rhabdomyosarcoma and H460 models. All animals were randomized over either the treatment or the control group. These groups were both treated with either NaCl or TH-302 (rhabdomysarcoma 25mg/kg, H4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ef10444d32f4585bffc73072d44b10
https://doi.org/10.1158/1078-0432.22456650.v1
https://doi.org/10.1158/1078-0432.22456650.v1