Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jessica Cowell"'
Publikováno v:
Dermatology and Therapy, Vol 10, Iss 3, Pp 503-513 (2020)
Abstract Introduction There is currently no consensus in the literature concerning the impact of aging on the properties of hyaluronan (HA) in the subcutaneous (SC) space. Recombinant human hyaluronidase PH20 (rHuPH20) facilitates SC administration o
Externí odkaz:
https://doaj.org/article/c223b4dc9f09491eb56f35542dcfc11e
Autor:
Caglar Cekic, Ozgur Sahin, Christopher D. Thanos, Joel Linden, Silvia Deaglio, H. Michael Shepard, Xiaoming Li, Michael J. LaBarre, Lei Huang, Kim B. Phan, Qiping Zhao, Renee Clift, Hong Pei, Sara Serra, Pelin G. Ersan, Mertkaya Aras, Ozge Saatci, Jessica Cowell, Luz M. Londono, Lin Wang
Supplementary Table 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d72a8b0e03229bebd0a5ae110699f11
https://doi.org/10.1158/0008-5472.22428382.v1
https://doi.org/10.1158/0008-5472.22428382.v1
Autor:
Caglar Cekic, Ozgur Sahin, Christopher D. Thanos, Joel Linden, Silvia Deaglio, H. Michael Shepard, Xiaoming Li, Michael J. LaBarre, Lei Huang, Kim B. Phan, Qiping Zhao, Renee Clift, Hong Pei, Sara Serra, Pelin G. Ersan, Mertkaya Aras, Ozge Saatci, Jessica Cowell, Luz M. Londono, Lin Wang
Supplementary Figure S1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0253382f52d2980d9447dcdfb9263c9
https://doi.org/10.1158/0008-5472.22428394
https://doi.org/10.1158/0008-5472.22428394
Autor:
Caglar Cekic, Ozgur Sahin, Christopher D. Thanos, Joel Linden, Silvia Deaglio, H. Michael Shepard, Xiaoming Li, Michael J. LaBarre, Lei Huang, Kim B. Phan, Qiping Zhao, Renee Clift, Hong Pei, Sara Serra, Pelin G. Ersan, Mertkaya Aras, Ozge Saatci, Jessica Cowell, Luz M. Londono, Lin Wang
Extracellular adenosine in tumors can suppress immune responses and promote tumor growth. Adenosine deaminase 2 (ADA2) converts adenosine into inosine. The role of ADA2 in cancer and whether it can target adenosine for cancer therapy has not been inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c2abcb266f7c6f929463efb4bc5a20
https://doi.org/10.1158/0008-5472.c.6513007
https://doi.org/10.1158/0008-5472.c.6513007
Autor:
Pelin Gülizar Ersan, Hong Pei, Joel Linden, Sara Serra, Kim Phan, Qiping Zhao, Caglar Cekic, Renee Clift, H. Michael Shepard, Lei Huang, Michael J. LaBarre, Mertkaya Aras, Christopher D. Thanos, Lin Wang, Ozgur Sahin, Jessica Cowell, Xiaoming Li, Silvia Deaglio, Luz Marina Londoño, Ozge Saatci
Publikováno v:
Cancer Research. 81:3319-3332
Extracellular adenosine in tumors can suppress immune responses and promote tumor growth. Adenosine deaminase 2 (ADA2) converts adenosine into inosine. The role of ADA2 in cancer and whether it can target adenosine for cancer therapy has not been inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a9c8945b30991ef06df0416d4ec6c3
https://doi.org/10.1158/0008-5472.can-21-0340
https://doi.org/10.1158/0008-5472.can-21-0340
Publikováno v:
Drug Metabolism and Drug Interactions. 36:155-163
Objectives Drug–drug interaction studies for hyaluronidase safety assessments have evaluated only animal-derived enzyme preparations. We therefore set out to evaluate whether high-dose administration of two antihistamines, a potent corticosteroid,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531cc072a99e3f6275741bd858b1eef5
https://doi.org/10.1515/dmpt-2020-0120
https://doi.org/10.1515/dmpt-2020-0120
Publikováno v:
Dermatology and Therapy, Vol 10, Iss 3, Pp 503-513 (2020)
Dermatology and Therapy
Dermatology and Therapy
Introduction There is currently no consensus in the literature concerning the impact of aging on the properties of hyaluronan (HA) in the subcutaneous (SC) space. Recombinant human hyaluronidase PH20 (rHuPH20) facilitates SC administration of injecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f49be4c5c5f6b3ef484c6eb72bdc53
https://doaj.org/article/c223b4dc9f09491eb56f35542dcfc11e
https://doaj.org/article/c223b4dc9f09491eb56f35542dcfc11e
Autor:
Xin Zhang, Dayong Zhai, Maria Barrera, Ung Jane, Vivian Nguyen, Dong J. Lee, Herve Aloysius, Wei Deng, Evan Rogers, Jessica Cowell, Ana Parra, Han Zhang, Brion W. Murray
Publikováno v:
Molecular cancer therapeutics. 20(9)
Since 2011, with the approval of crizotinib and subsequent approval of four additional targeted therapies, anaplastic lymphoma kinase (ALK) inhibitors have become important treatments for a subset of patients with lung cancer. Each generation of ALK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5467a422b080aefa64bc71e0aaeb28da
https://pubmed.ncbi.nlm.nih.gov/34158340
https://pubmed.ncbi.nlm.nih.gov/34158340
Autor:
Clifford J. Whatcott, Sanna Rosengren, Michael J. LaBarre, Barbara Blouw, Ryan J. Osgood, Chunmei Zhao, Haiyong Han, Xiaoming Li, Daniel C. Maneval, Curtis B. Thompson, Jessica Cowell, Daniel D. Von Hoff, Darin Taverna, Mark D. Pagel, Sheryl Garrovillo, H. Michael Shepard
Publikováno v:
Clinical Cancer Research. 24:4798-4807
Purpose: The tumor microenvironment (TME) evolves to support tumor progression. One marker of more aggressive malignancy is hyaluronan (HA) accumulation. Here, we characterize biological and physical changes associated with HA-accumulating (HA-high)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa6be1db6ca85b0d82da641b601d55e
https://doi.org/10.1158/1078-0432.ccr-17-3284
https://doi.org/10.1158/1078-0432.ccr-17-3284
Autor:
Han Zhang, Dayong Zhai, Herve Aloysius, Evan Rogers, Xin Zhang, Ana Parra, Vivian Nguyen, Ung Jane, Dong Lee, Wei Deng, Maria Barrera, Jessica Cowell, Brion W. Murray
Publikováno v:
Cancer Research. 81:1469-1469
Three generations of ALK inhibitors are approved for the treatment of ALK+ NSCLC but their efficacy is often limited by ALK resistance mutations. The solvent front mutation G1202R and gatekeeper mutation L1196M are major resistance mechanisms to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e92a6cbe4f3f3dde1b53046b035905
https://doi.org/10.1158/1538-7445.am2021-1469
https://doi.org/10.1158/1538-7445.am2021-1469