Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jessica Calloway"'
Autor:
Inish O'Doherty, Brandon Pabst, Adam M. Gilbert, Kimberly F. Fennell, Chris Limberakis, Jinshan Chen, Jayvardhan Pandit, Matthew Frank Brown, Markus Boehm, Rushi Patel, Jeffrey A. Pfefferkorn, Jemy A. Gutierrez, Robert M. Oliver, Jiangli Yan, Jeremy T. Starr, Kay Ahn, Brandon P. Schuff, Amit S. Kalgutkar, Kieran F. Geoghegan, Kevin D. Parris, Veerabahu Shanmugasundaram, Cecile Vernochet, Timothy P. Rolph, Ye Che, Nicholas B. Vera, Alison H. Varghese, Adhiraj Lanba, Magee Thomas Victor, Jessica Calloway
Publikováno v:
ACS chemical biology. 11(9)
Lysophospholipase-like 1 (LYPLAL1) is an uncharacterized metabolic serine hydrolase. Human genome-wide association studies link variants of the gene encoding this enzyme to fat distribution, waist-to-hip ratio, and nonalcoholic fatty liver disease. W
Autor:
John Litchfield, Margit MacDougall, Brendan J. Murphy, Kevin B. Bahnck, Yan Zhang, Karen Atkinson, Mike Gumkowski, Charanjeet Jassal, Anthony Carlo, Benjamin D. Stevens, Jessica Calloway, Charles J. Rotter, Paul A. Amor, Martin A. Berliner, Kevin J. Filipski, Paul Nkansah, John C. Pettersen, Jeffrey A. Pfefferkorn, David R. Derksen, Christian Perreault
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(24)
Glucokinase (hexokinase IV) continues to be a compelling target for the treatment of type 2 diabetes given the wealth of supporting human genetics data and numerous reports of robust clinical glucose lowering in patients treated with small molecule a