Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jessica C Tempany"'
Autor:
Ajithkumar Vasanthakumar, Yang Liao, Peggy Teh, Maria F. Pascutti, Anna E. Oja, Alexandra L. Garnham, Renee Gloury, Jessica C. Tempany, Tom Sidwell, Eloy Cuadrado, Paul Tuijnenburg, Taco W. Kuijpers, Najoua Lalaoui, Lisa A. Mielke, Vanessa L. Bryant, Philip D. Hodgkin, John Silke, Gordon K. Smyth, Martijn A. Nolte, Wei Shi, Axel Kallies
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2906-2920 (2017)
After exiting the thymus, Foxp3+ regulatory T (Treg) cells undergo further differentiation in the periphery, resulting in the generation of mature, fully suppressive effector (e)Treg cells in a process dependent on TCR signaling and the transcription
Externí odkaz:
https://doaj.org/article/a6158e2926c7412c92b606577bc61e39
Autor:
Isabella Y. Kong, Stephanie Trezise, Amanda Light, Izabela Todorovski, Gisela Mir Arnau, Sreeja Gadipally, David Yoannidis, Kaylene J. Simpson, Xueyi Dong, Lachlan Whitehead, Jessica C. Tempany, Anthony J. Farchione, Amania A. Sheikh, Joanna R. Groom, Kelly L. Rogers, Marco J. Herold, Vanessa L. Bryant, Matthew E. Ritchie, Simon N. Willis, Ricky W. Johnstone, Philip D. Hodgkin, Stephen L. Nutt, Stephin J. Vervoort, Edwin D. Hawkins
Publikováno v:
Cell death and differentiation. 29(12)
High-throughput methodologies are the cornerstone of screening approaches to identify novel compounds that regulate immune cell function. To identify novel targeted therapeutics to treat immune disorders and haematological malignancies, there is a ne
Superior properties of CellTrace Yellow™ as a division tracking dye for human and murine lymphocytes
Publikováno v:
Immunology and Cell Biology
The discovery of cell division tracking properties of 5‐(and‐6)‐carboxyfluorescein diacetate succinimidyl ester (CFSE) by Lyons and Parish in 1994 led to a broad range of new methods and numerous important biological discoveries. After labeling
Autor:
Charles R. Mackay, David M. Tarlinton, Inge Baas, Dana Piovesan, Andrea Di Pietro, Yunshun Chen, Kristy O'Donnell, Jessica C Tempany, Victor Peperzak, Gordon K. Smyth, Kim L. Good-Jacobson, Gabrielle T. Belz, Callisthenis Yiannis, Joanna R Groom
Publikováno v:
Cell Reports, Vol 19, Iss 3, Pp 461-470 (2017)
Summary: Humoral immune responses are tailored to the invading pathogen through regulation of key transcription factors and their networks. This is critical to establishing effective antibody-mediated responses, yet it is unknown how B cells integrat
Autor:
A. Farchione, Vanessa L. Bryant, Philip D. Hodgkin, Franciscus Kroese, Gwenny M Verstappen, S. Downie-Doyle, Hendrika Bootsma, H. Cheon, Maureen Rischmueller, Ken R. Duffy, Jessica C Tempany
Publikováno v:
Annals of the Rheumatic Diseases. 79:1372-1373
Background:Primary Sjögren’s syndrome (pSS) is a heterogeneous immune disorder with broad clinical phenotypes that can arise from a large number of genetic, hormonal, and environmental causes. B-cell hyperactivity is considered to be a pathogenic
Autor:
Colleen Elizabeth D'Arcy, Thomas S. Scerri, Kathy Nicholls, Alexander Strathmore, Steven Megaloudis, Jessica C Tempany, Catriona McLean, Jo A Douglass, Charlotte Slade, Philip D. Hodgkin, Tran Binh Giang, Vanessa L. Bryant, Melanie Bahlo
Publikováno v:
Journal of clinical immunology. 39(3)
Common variable immunodeficiency is the most prevalent of the primary immunodeficiency diseases, yet its pathogenesis is largely poorly understood. Of the cases that are monogenic, many arise due to pathogenic variants in NFKB1 and NFKB2. Here, we re
Autor:
Peggy P Teh, Najoua Lalaoui, Maria Fernanda Pascutti, Yang Liao, Vanessa L. Bryant, Jessica C Tempany, Taco W. Kuijpers, Axel Kallies, Philip D. Hodgkin, Paul Tuijnenburg, Lisa A. Mielke, Martijn A. Nolte, Renee Gloury, Gordon K. Smyth, Alexandra L. Garnham, Anna E. Oja, Eloy Cuadrado, Tom Sidwell, Wei Shi, Ajithkumar Vasanthakumar, John Silke
Publikováno v:
Cell reports, 20(12), 2906-2920. Cell Press
Cell Reports, Vol 20, Iss 12, Pp 2906-2920 (2017)
Cell Reports, Vol 20, Iss 12, Pp 2906-2920 (2017)
After exiting the thymus, Foxp3(+) regulatory T (Treg) cells undergo further differentiation in the periphery, resulting in the generation of mature, fully suppressive effector (e) Treg cells in a process dependent on TCR signaling and the transcript
Autor:
Thomas S. Scerri, Jessica C Tempany, Euphemia Leung, See-Tarn Woon, Philip D. Hodgkin, Vanessa L. Bryant, Bodo Grimbacher, Charlotte A. Slade, Rohan Ameratunga, Jos W. M. van der Meer, Jo A Douglass, Manfred Fliegauf
Publikováno v:
Pathology. 49:S45-S46
Autor:
Philip D. Hodgkin, Charlotte A. Slade, See-Tarn Woon, Euphemia Leung, Peter Browett, Jessica C Tempany, Anselm Enders, Vanessa L. Bryant, Wikke Koopmans, Rohan Ameratunga, Klaus Lehnert, Richard Steele
Publikováno v:
Clinical & Translational Immunology
Common variable immunodeficiency disorders (CVID) are a group of primary immunodeficiencies where monogenetic causes account for only a fraction of cases. On this evidence, CVID is potentially polygenic and epistatic although there are, as yet, no ex