Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jessica C Graham"'
Autor:
Xuefeng Ren, Jessica C Graham, Lichen Jing, Andrei M Mikheev, Yuan Gao, Jenny Pan Lew, Hong Xie, Andrea S Kim, Xiuling Shang, Cynthia Friedman, Graham Vail, Ming Zhu Fang, Yana Bromberg, Helmut Zarbl
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e70930 (2013)
Rat strains differ dramatically in their susceptibility to mammary carcinogenesis. On the assumption that susceptibility genes are conserved across mammalian species and hence inform human carcinogenesis, numerous investigators have used genetic link
Externí odkaz:
https://doaj.org/article/95b43a43dbe84d18999ebbd5d660546d
Autor:
Jessica C Graham, Helmut Zarbl
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36103 (2012)
Disease-specific biomarkers are an important tool for the timely and effective management of pathological conditions, including determination of susceptibility, diagnosis, and monitoring efficacy of preventive or therapeutic strategies. Aptamers, com
Externí odkaz:
https://doaj.org/article/36838577bdbe444ebf9ddd9a05a2e317
Autor:
Jessica C. Graham, Lisa Wong, Adeyemi O. Adedeji, Aija Kusi, Becky Lee, Donna Lee, Noel Dybdal
Publikováno v:
Animals, Vol 13, Iss 24, p 3863 (2023)
Based on the current state of science, the use of animals remains essential in bringing safe and effective medicines to patients. Respect for laboratory animal welfare and the application of 3Rs principles (the replacement, reduction, and refinement
Externí odkaz:
https://doaj.org/article/209b4c4d48d4420bb934a00ca7c28cb0
Publikováno v:
Appl Biosaf
Background: As the pharmaceutical industry advances its understanding of biological processes and how they relate to (the causes and treatments of) disease, many new modalities such as protein therapeutics (PTs) are emerging as breakthrough therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2838caca677cdee22bd7530b1b12b4
https://pubmed.ncbi.nlm.nih.gov/36034098
https://pubmed.ncbi.nlm.nih.gov/36034098
Publikováno v:
The Journal of Organic Chemistry. 87:14993-14994
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80bf3fe3aa9a4f3e85f5280dbe26e6b
https://doi.org/10.1021/acs.joc.2c01888
https://doi.org/10.1021/acs.joc.2c01888
Autor:
Jessica C. Graham, Alejandra Trejo-Martin, Martyn L. Chilton, Jakub Kostal, Joel Bercu, Gregory L. Beutner, Uma S. Bruen, David G. Dolan, Stephen Gomez, Jedd Hillegass, John Nicolette, Matthew Schmitz
Publikováno v:
Chemical research in toxicology. 35(6)
Peptide couplers (also known as amide bond-forming reagents or coupling reagents) are broadly used in organic chemical syntheses, especially in the pharmaceutical industry. Yet, occupational health hazards associated with this chemical class are larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ea18af40f3631f3592327aa4d47482
https://pubmed.ncbi.nlm.nih.gov/35532537
https://pubmed.ncbi.nlm.nih.gov/35532537
Autor:
Joel P. Bercu, Ailis Maisey, Alejandra Trejo-Martin, Melisa Masuda-Herrera, John Nicolette, Erika Udovic, Elizabeth A. Martin, Eric Dowdy, James Harvey, Angela White, Susanne Glowienke, Michelle O. Kenyon, Jessica C. Graham, Mark W. Powley, Patricia Parris
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 126
The presence of impurities in drugs is unavoidable. As impurities offer no direct benefit to the patient, it is critical that impurities do not compromise patient safety. Current guidelines on the derivation of acceptable impurity levels leave aspect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b37d8297b148acddb2ccc507898137f
https://pubmed.ncbi.nlm.nih.gov/34363920
https://pubmed.ncbi.nlm.nih.gov/34363920
Autor:
Colin Owens, Jessica C. Graham, Russell Naven, Glenn J. Myatt, Joel P. Bercu, Raymond Kemper, Iris van de Gevel, Surya Hari Lal, Kathleen Vriens, Melisa Masuda-Herrera, Phillip Bellion, Alejandra Trejo-Martin, Sarah Whalley, Lawrence Milchak, Richard L. Marchese Robinson, Anna Vuorinen, Catrin Hasselgren, Pierre Ferrer, William A. Hawkins, Matthew Schmitz, Kamila Gromek, Jean Lord
Publikováno v:
Regul Toxicol Pharmacol
This study assesses whether currently available acute oral toxicity (AOT) in silico models, provided by the widely employed Leadscope software, are fit-for-purpose for categorization and labelling of chemicals. As part of this study, a large data set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964e311259d8ebd3de6475fb86827f15
https://pubmed.ncbi.nlm.nih.gov/35474000
https://pubmed.ncbi.nlm.nih.gov/35474000
Autor:
Hiroyuki Takahashi, Denise L. Faustman, Gabriella F. Shpilsky, Jessica C. Graham, Ryan C. Keefe, Louisa Moore, Yaerin Song, Trevor G. Luck, Lisa Tran, Willem M. Kühtreiber, Sarah M. Sinton
Publikováno v:
iScience
iScience, Vol 23, Iss 5, Pp-(2020)
iScience, Vol 23, Iss 5, Pp-(2020)
Summary Myc has emerged as a pivotal transcription factor for four metabolic pathways: aerobic glycolysis, glutaminolysis, polyamine synthesis, and HIF-1α/mTOR. Each of these pathways accelerates the utilization of sugar. The BCG vaccine, a derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8880d16c66540356ea115c8f549aee79
https://pubmed.ncbi.nlm.nih.gov/32380424
https://pubmed.ncbi.nlm.nih.gov/32380424
Autor:
Glenn J. Myatt, Arianna Bassan, Dave Bower, Kevin M. Crofton, Kevin P. Cross, Jessica C. Graham, Catrin Hasselgren, Robert A. Jolly, Scott Miller, Manuela Pavan, Raymond R Tice, Craig Zwickl, Candice Johnson
Publikováno v:
Computational Toxicology. 21:100209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::561e0b8c61bff89be3a7e52ce777e46f
https://doi.org/10.1016/j.comtox.2021.100209
https://doi.org/10.1016/j.comtox.2021.100209