Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jessica Bowers"'
Autor:
Grace A. McCarthy, Aditi Jain, Roberto Di Niro, Christopher W. Schultz, Wei Jiang, Charles J Yeo, Jessica Bowers, Jennifer Finan, Kelly Rhodes, Lou Casta, Vivi Hou, Anthony Stefanoni, Samantha Z. Brown, Avinoam Nevler, Lebaron C. Agostini, Lori Getts, Robert Getts, Jonathan R. Brody
Publikováno v:
Translational Oncology, Vol 32, Iss , Pp 101662- (2023)
Introduction: Standard-of-care systemic chemotherapies for pancreatic ductal adenocarcinoma (PDAC) currently have limited clinical benefits, in addition to causing adverse side effects in many patients. One factor known to contribute to the poor chem
Externí odkaz:
https://doaj.org/article/1a3343d576a846809073e9eb6d5af670
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 2, Pp n/a-n/a (2021)
Abstract Biodistribution studies are essential in drug carrier design and translation, and radiotracing provides a sensitive quantitation for this purpose. Yet, for biodegradable formulations, small amounts of free‐label signal may arise prior to o
Externí odkaz:
https://doaj.org/article/2a4a4d1b2a5648f9b3b88cead5a879eb
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1496 (2022)
3DNA holds promise as a carrier for drugs that can be intercalated into its core or linked to surface arms. Coupling 3DNA to an antibody targeting intercellular adhesion molecule 1 (ICAM-1) results in high lung-specific biodistributions in vivo. Whil
Externí odkaz:
https://doaj.org/article/dfc3a178d5a844d2847032fecb93661d
Publikováno v:
Clinical Pathology, Vol 13 (2020)
The tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase 2 (IDO2) has been identified as an immunomodulatory agent promoting autoimmunity in preclinical models. As such, finding ways to target the expression of IDO2 in B cells promises a new av
Externí odkaz:
https://doaj.org/article/1733ccdba2c8400ba5b3bb38e6d401ae
Autor:
Jacquelyn Gerhart, Jessica Bowers, Lindsay Gugerty, Colby Gerhart, Mark Martin, Fathma Abdalla, Arturo Bravo-Nuevo, Jonathan Tabb Sullivan, Rebecca Rimkunas, Amie Albertus, Lou Casta, Lori Getts, Robert Getts, Mindy George-Weinstein
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0234792 (2020)
The Myo/Nog cell lineage was discovered in the chick embryo and is also present in adult mammalian tissues. The cells are named for their expression of mRNA for the skeletal muscle specific transcription factor MyoD and bone morphogenetic protein inh
Externí odkaz:
https://doaj.org/article/1b8e56c925d24a87848399202e4d3c79
Autor:
Radha Duttagupta, Sharon DiRienzo, Rong Jiang, Jessica Bowers, Jeremy Gollub, Jessica Kao, Keith Kearney, David Rudolph, Noor B Dawany, Michael K Showe, Tom Stamato, Robert C Getts, Keith W Jones
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31241 (2012)
Inflammatory Bowel Disease--comprised of Crohn's Disease and Ulcerative Colitis (UC)--is a complex, multi-factorial inflammatory disorder of the gastrointestinal tract. In this study we have explored the utility of naturally occurring circulating miR
Externí odkaz:
https://doaj.org/article/d8bc3b8684474870977ac1f591a84622
Autor:
Ali Vaziri-Gohar, Joel Cassel, Farheen S. Mohammed, Mehrdad Zarei, Jonathan J. Hue, Omid Hajihassani, Hallie J. Graor, Yellamelli V. V. Srikanth, Saadia A. Karim, Ata Abbas, Erin Prendergast, Vanessa Chen, Erryk S. Katayama, Katerina Dukleska, Imran Khokhar, Anthony Andren, Li Zhang, Chunying Wu, Bernadette Erokwu, Chris A. Flask, Mahsa Zarei, Rui Wang, Luke D. Rothermel, Andrea M. P. Romani, Jessica Bowers, Robert Getts, Curtis Tatsuoka, Jennifer P. Morton, Ilya Bederman, Henri Brunengraber, Costas A. Lyssiotis, Joseph M. Salvino, Jonathan R. Brody, Jordan M. Winter
Publikováno v:
Nature Cancer. 3:852-865
Nutrient-deprived conditions in the tumor microenvironment (TME) restrain cancer cell viability due to increased free radicals and reduced energy production. In pancreatic cancer cells a cytosolic metabolic enzyme, wild-type isocitrate dehydrogenase
Publikováno v:
Journal of Comparative Physiology A. 207:575-594
CREB (cAMP response element-binding) transcription factors are conserved markers of memory formation in the brain and peripheral circuits. We provide immunohistochemical evidence of CREB phosphorylation in the dwarf cuttlefish, Sepia bandensis, follo
Autor:
Laura L. Osorno, Robert J. Mosley, Patricia L. Poley, Jessica Bowers, Grzegorz Gorski, Jacquelyn Gerhart, Robert Getts, Mindy George-Weinstein, Mark E. Byrne
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics.
Publikováno v:
Learning & Behavior. 48:420-431
Measuring behavior in the form of numerical data is difficult, especially for studies involving complex actions. DanioVision is a closed-chamber system that utilizes subject tracking to comprehensively record behavior, while also mitigating the influ