Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jessica Bourque"'
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151242- (2022)
Homeodomain only protein (Hopx, HOPX) is a highly evolutionarily conserved, homeodomain-containing, small protein expressed in multiple tissues and cell types, including those of hematopoietic origin. The quasi-ubiquitous presence of Hopx contrasts w
Externí odkaz:
https://doaj.org/article/5e16c82d2c6248d39ec21739c7a747bf
Autor:
Jessica Bourque, Daniel Hawiger
Publikováno v:
Biology, Vol 12, Iss 5, p 716 (2023)
T cell responses to cognate antigens crucially depend on the specific functionality of dendritic cells (DCs) activated in a process referred to as maturation. Maturation was initially described as alterations of the functional status of DCs in direct
Externí odkaz:
https://doaj.org/article/52b492e3a3cd4052a966640b05538edc
Autor:
Jessica Bourque, Adeleye Opejin, Alexey Surnov, Courtney A. Iberg, Cindy Gross, Rajan Jain, Jonathan A. Epstein, Daniel Hawiger
Publikováno v:
Heliyon, Vol 7, Iss 11, Pp e08311- (2021)
Homeodomain only protein (Hopx) is a regulator of cell differentiation and function, and it has also emerged as a crucial marker of specific developmental and differentiation potentials. Hopx expression and functions have been identified in some stem
Externí odkaz:
https://doaj.org/article/c7c4ba982f4e448781ed717303b4b161
Autor:
Jessica Bourque, Daniel Hawiger
Publikováno v:
Antibodies, Vol 11, Iss 1, p 8 (2022)
Recombinant immunoglobulins, derived from monoclonal antibodies recognizing the defined surface epitopes expressed on dendritic cells, have been employed for the past two decades to deliver antigens to dendritic cells in vivo, serving as critical too
Externí odkaz:
https://doaj.org/article/d3bd233592744dadaaac9113a54db39a
Autor:
Jessica Bourque, Daniel Hawiger
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/b4fe697a22354765bc633717d8401f9b
Autor:
Jessica Bourque, Daniel Hawiger
Publikováno v:
Trends in immunology.
In contrast to conventional dendritic cells (cDCs) that are constantly exposed to microbial signals at anatomical barriers, cDCs in systemic lymphoid organs are sheltered from proinflammatory stimulation in the steady state but respond to inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026c3504dd06b43f00a9cda7177bb4ef
https://pubmed.ncbi.nlm.nih.gov/36599743
https://pubmed.ncbi.nlm.nih.gov/36599743
Autor:
Daniel Hawiger, Jessica Bourque
Publikováno v:
Antibodies (Basel, Switzerland). 11(1)
Recombinant immunoglobulins, derived from monoclonal antibodies recognizing the defined surface epitopes expressed on dendritic cells, have been employed for the past two decades to deliver antigens to dendritic cells in vivo, serving as critical too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf2a3cac49fc9ad07aa3f1404e57f07
https://pubmed.ncbi.nlm.nih.gov/35225867
https://pubmed.ncbi.nlm.nih.gov/35225867
Autor:
Jessica Bourque, Daniel Hawiger
Publikováno v:
J Immunol
Conventional dendritic cells (cDC) control adaptive immunity by sensing damage- and pathogen-associated molecular patterns and then inducing defined differentiation programs in T cells. Nevertheless, in the absence of specific proimmunogenic innate s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda00620d40a3d27f454dad8488f96a8
https://pubmed.ncbi.nlm.nih.gov/35042789
https://pubmed.ncbi.nlm.nih.gov/35042789
Autor:
Jessica, Bourque, Daniel, Hawiger
Publikováno v:
Mo Med
Despite substantial progress in developing new immunotherapies against multiple sclerosis (MS), currently available immunotherapies are only partially effective for this debilitating neurological disease, thus necessitating new therapeutic approaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8ca46d8d497e1d58ce9b5e0f209255f
https://pubmed.ncbi.nlm.nih.gov/34373668
https://pubmed.ncbi.nlm.nih.gov/34373668
Publikováno v:
Cell reports. 39(2)
It remains unclear how the pro-immunogenic maturation of conventional dendritic cells (cDCs) abrogates their tolerogenic functions. Here, we report that the loss of tolerogenic functions depends on the rapid death of BTLA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5510abd8ca846ad7cff053461d4776ae
https://pubmed.ncbi.nlm.nih.gov/35417681
https://pubmed.ncbi.nlm.nih.gov/35417681