Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jessica Boulos"'
Autor:
Timothy Samec, Kharimat Lora Alatise, Jessica Boulos, Serena Gilmore, Anthony Hazelton, Carleigh Coffin, Angela Alexander-Bryant
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 95-111 (2022)
Ovarian cancer has shown little improvement in survival among advanced-stage patients over the past decade. Current treatment strategies have been largely unsuccessful in treating advanced disease, with many patients experiencing systemic toxicity an
Externí odkaz:
https://doaj.org/article/6a4af8abcae046f6ba6452cffbc2e0ab
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100248- (2022)
Current delivery strategies for cancer therapeutics commonly cause significant systemic side effects due to required high doses of therapeutic, inefficient cellular uptake of drug, and poor cell selectivity. Peptide-based delivery systems have shown
Externí odkaz:
https://doaj.org/article/6a31904a838842e6914e9ebd2677ce18
Publikováno v:
Materials today. Bio. 14
Current delivery strategies for cancer therapeutics commonly cause significant systemic side effects due to required high doses of therapeutic, inefficient cellular uptake of drug, and poor cell selectivity. Peptide-based delivery systems have shown
Publikováno v:
Cancer Research. 81:1310-1310
Glioblastoma Multiforme (GBM), a grade VI glioma, is an aggressive malignant tumorwith a poor prognosis. With an incidence rate of 3.19 per 100,000, GBM has a median survivalrate of 12-15 months and a five-year survival rate of less than 5%. Typical
Publikováno v:
Cancer Research. 81:304-304
Background Ovarian cancer (OC) is among the most commonly diagnosed cancers and combined with the low responses to therapeutics, it has the highest mortality among gynecological cancers. When diagnosed at stage III and stage IV, survival rates remain
Publikováno v:
Cancer Research. 80:2868-2868
Introduction: Ovarian cancer recurrence and survival rates have remained stagnant over time with current therapeutics displaying low efficacy and often rendered ineffective by degradation. This work presents novel fusogenic peptides that will electro