Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jessica Blumenfeld"'
Autor:
Elise Marsan, Dmitry Velmeshev, Arren Ramsey, Ravi K. Patel, Jiasheng Zhang, Mark Koontz, Madeline G. Andrews, Martina de Majo, Cristina Mora, Jessica Blumenfeld, Alissa N. Li, Salvatore Spina, Lea T. Grinberg, William W. Seeley, Bruce L. Miller, Erik M. Ullian, Matthew F. Krummel, Arnold R. Kriegstein, Eric J. Huang
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Mutations in the human progranulin (GRN) gene are a leading cause of frontotemporal lobar degeneration (FTLD). While previous studies implicate aberrant microglial activation as a disease-driving factor in neurodegeneration in the thalamocortical cir
Externí odkaz:
https://doaj.org/article/7f87fa9f28bd4ee9be391db5a7643359
Autor:
Nicole Koutsodendris, Jessica Blumenfeld, Ayushi Agrawal, Michela Traglia, Brian Grone, Misha Zilberter, Oscar Yip, Antara Rao, Maxine R. Nelson, Yanxia Hao, Reuben Thomas, Seo Yeon Yoon, Patrick Arriola, Yadong Huang
Publikováno v:
Nature aging, vol 3, iss 3
Apolipoprotein E4 (APOE4) is the strongest known genetic risk factor for late-onset Alzheimer’s disease (AD). Conditions of stress or injury induce APOE expression within neurons, but the role of neuronal APOE4 in AD pathogenesis is still unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afe5e2b3e90921ae536bd6d7cbbba0d
https://escholarship.org/uc/item/3mn2s8w7
https://escholarship.org/uc/item/3mn2s8w7