Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jessica Bertolini"'
An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development
Autor:
Sara Mercurio, Chiara Alberti, Linda Serra, Simone Meneghini, Pietro Berico, Jessica Bertolini, Andrea Becchetti, Silvia K. Nicolis
Publikováno v:
Open Biology, Vol 11, Iss 2 (2021)
The hippocampus is a brain area central for cognition. Mutations in the human SOX2 transcription factor cause neurodevelopmental defects, leading to intellectual disability and seizures, together with hippocampal dysplasia. We generated an allelic se
Externí odkaz:
https://doaj.org/article/caad3cf9db984a11b732b669f874a156
Autor:
Simone Meneghini, Silvia K. Nicolis, Sara Mercurio, Pietro Berico, Linda Serra, Jessica Bertolini, Andrea Becchetti, Chiara Alberti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5fb5ea6c74f0e36ef6174b6c0c1dad1
https://doi.org/10.1098/rsob.200339/v2/response1
https://doi.org/10.1098/rsob.200339/v2/response1
An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development
Autor:
Pietro Berico, Simone Meneghini, Sara Mercurio, Silvia K. Nicolis, Linda Serra, Andrea Becchetti, Chiara Alberti, Jessica Bertolini
Publikováno v:
Open Biology, Vol 11, Iss 2 (2021)
The hippocampus is a brain area central for cognition. Mutations in the human SOX2 transcription factor cause neurodevelopmental defects, leading to intellectual disability and seizures, together with hippocampal dysplasia. We generated an allelic se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321a4a49952e99c15d638569d4bdf812
http://hdl.handle.net/10281/362440
http://hdl.handle.net/10281/362440
Autor:
Silvia K. Nicolis, Pietro Berico, Jessica Bertolini, Sara Mercurio, Linda Serra, Chiara Alberti, Andrea Becchetti, Simone Meneghini
The hippocampus is a brain area central for cognition. Mutations in the human SOX2 transcription factor cause neurodevelopmental defects, leading to intellectual disability and seizures, together with hippocampal dysplasia. We generated an allelic se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f370de47c99ed0f74710558255b8b12
https://doi.org/10.1101/2020.08.16.252684
https://doi.org/10.1101/2020.08.16.252684
Autor:
Maria Antonietta Rizzuto, Miriam Colombo, Lucia Salvioni, Jessica Bertolini, Davide Prosperi, Laura Pandolfi
Publikováno v:
Cancers
Starting with the enhanced permeability and retention (EPR) effect discovery, nanomedicine has gained a crucial role in cancer treatment. The advances in the field have led to the approval of nanodrugs with improved safety profile and still inspire t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebfb1e7e2eea8d82ba23a8fee9d8937
http://europepmc.org/articles/PMC6966668
http://europepmc.org/articles/PMC6966668
Autor:
Sara Mercurio, Tamilarasan K. Panaliappan, Cedric Patthey, Lena Gunhaga, Vijay K. Jidigam, Soufien Sghari, Raj Bose, Silvia K. Nicolis, Walter Wittmann, Jessica Bertolini
Publikováno v:
Development (Cambridge, England)
The transcription factor Sox2 is necessary to maintain pluripotency of embryonic stem cells, and to regulate neural development. Neurogenesis in the vertebrate olfactory epithelium persists from embryonic stages through adulthood. The role Sox2 plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba533d9ac3fb433f997bb930feb5449
http://europepmc.org/articles/PMC5825848
http://europepmc.org/articles/PMC5825848
Autor:
Menno P. Creyghton, Silvia K. Nicolis, Federico Zambelli, Yanfen Zhu, Paul Robson, Rebecca Favaro, Jessica Bertolini, Ben Martynoga, Paola Bovolenta, Marcos J. Cardozo, Chee Hong Wong, Noemi Tabanera, Sergio Ottolenghi, Cristiana Barone, Giulio Pavesi, Chew Yee Ngan, Chia-Lin Wei, Marit W. Vermunt, Harianto Tjong, Sara Mercurio, Miriam Pagin, Jessica Mariani, François Guillemot
Publikováno v:
Cell Stem Cell, 24(3), 462-476.e6. Cell Press
We recently investigated the prognostic impact of a Chronic Care Model (CCM)-based healthcare program applied in primary care in Tuscany Region mainly run by multidisciplinary teams composed of general practitioners (GPs) and nurses. The project incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1417c05c1907c5d06f36f41d04ca6fd6
https://doi.org/10.1016/j.stem.2019.02.004
https://doi.org/10.1016/j.stem.2019.02.004
Autor:
Essam M. Abdelalim, Natacha A. Agabalyan, Parth Armin, Jessica Bertolini, Jeff Biernaskie, Ian Chambers, Kathryn S.E. Cheah, G. Marius Clore, Mohamed M. Emara, Rebecca Favaro, Andrew Hagner, Yasuo Ishii, Ian Jacobs, Ming Jiang, Yusuke Kamachi, Prasanna R. Kolatkar, Hisato Kondoh, Wei-Yao Ku, Robin Lovell-Badge, Jessica Mariani, Sara Mercurio, Balasubramanian Moovarkumudalvan, Jonas Muhr, Nicholas P. Mullin, Silvia K. Nicolis, Sergio Ottolenghi, Raymond A. Poot, Nilima Prakash, Jianwen Que, Waleed Rahmani, Karine Rizzoti, Masanori Uchikawa, Veronica van Heyningen, Frederick C.K. Wong, Neng Chun Wong, Pin-Xian Xu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63e3ba0bfd18ec3297344d0e141a8adc
https://doi.org/10.1016/b978-0-12-800352-7.01002-1
https://doi.org/10.1016/b978-0-12-800352-7.01002-1
Autor:
Silvia K. Nicolis, Jessica Bertolini, Rebecca Favaro, Sergio Ottolenghi, Jessica Mariani, Sara Mercurio
The essential role of SOX2 in embryogenesis was first demonstrated by the Sox2 gene knockout in mouse, leading to early embryonic lethality by loss of the epiblast, the founder tissue of the embryo proper. However, later in development, SOX2 expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eef384d50fae09cd496a54645e37a62
http://hdl.handle.net/10281/152539
http://hdl.handle.net/10281/152539
Autor:
Jessica Bertolini, Davide De Pietri Tonelli, Rebecca Favaro, Francisco Nieto-Lopez, Leonardo Beccari, Anna Ferri, Paola Bovolenta, Sergio Ottolenghi, Cristina Verzeroli, Sara Mercurio, Federico La Regina, Silvia K. Nicolis
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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instname
The Sox2 transcription factor is active in stem/progenitor cells throughout the developing vertebrate central nervous system. However, its conditional deletion at E12.5 in mouse causes few brain developmental problems, with the exception of the postn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a8e91f641c2443cb4f5391d0b3e174
https://pubmed.ncbi.nlm.nih.gov/23444355
https://pubmed.ncbi.nlm.nih.gov/23444355