Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jessica A. Neal"'
Autor:
Thomas Helleday, Katheryn Meek, Benedikt M. Kessler, Freddie C. Hamdy, Huahao Shen, Xinming Song, Joanna McGouran, Oliver Mortusewicz, Zhengqiang Bao, Jessica A. Neal, Annette L. Medhurst, Zhihui Chen, Songmin Ying
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63046f27f2ed54402fd23949fa76cd98
https://doi.org/10.1158/0008-5472.22411764.v1
https://doi.org/10.1158/0008-5472.22411764.v1
Autor:
Thomas Helleday, Katheryn Meek, Benedikt M. Kessler, Freddie C. Hamdy, Huahao Shen, Xinming Song, Joanna McGouran, Oliver Mortusewicz, Zhengqiang Bao, Jessica A. Neal, Annette L. Medhurst, Zhihui Chen, Songmin Ying
A series of critical pathways are responsible for the detection, signaling, and restart of replication forks that encounter blocks during S-phase progression. Small base lesions may obstruct replication fork progression and processing, but the link b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::361d727bfa99010c57d5878fb42ab6d2
https://doi.org/10.1158/0008-5472.c.6508290.v1
https://doi.org/10.1158/0008-5472.c.6508290.v1
Autor:
Thomas Helleday, Katheryn Meek, Benedikt M. Kessler, Freddie C. Hamdy, Huahao Shen, Xinming Song, Joanna McGouran, Oliver Mortusewicz, Zhengqiang Bao, Jessica A. Neal, Annette L. Medhurst, Zhihui Chen, Songmin Ying
Supplementary Figures. Sup. Fig. 1: Recuirtment of XRCC1 to stalled DNA replication forks is prevented by CtIP. Sup. Fig. 2: CK2 actiivty is required for stabilization of XRCC1 protein and its recuirtment to stalled forks. Sup. Fig. 3: Interaction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bf44daa454108d34aa053e4f9bf6ae
https://doi.org/10.1158/0008-5472.22411761
https://doi.org/10.1158/0008-5472.22411761
Publikováno v:
The Journal of Immunology. 197:3165-3174
The evidence that ATM affects resolution of RAG-induced DNA double-strand breaks is profuse and unequivocal; moreover, it is clear that the RAG complex itself cooperates (in an undetermined way) with ATM to facilitate repair of these double-strand br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f099227b7e7721de5270c526249077
https://doi.org/10.4049/jimmunol.1600597
https://doi.org/10.4049/jimmunol.1600597
Publikováno v:
The Journal of Immunology. 196:3032-3042
Unlike most DNA-dependent protein kinase, catalytic subunit (DNA-PKcs)–deficient mouse cell strains, we show in the present study that targeted deletion of DNA-PKcs in two different human cell lines abrogates VDJ signal end joining in episomal assa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114208aefb4570f392de3334a3061f7d
https://doi.org/10.4049/jimmunol.1501654
https://doi.org/10.4049/jimmunol.1501654
Publikováno v:
DNA Repair (Amst)
It has recently been established that the marked sensitivity of ATM deficient cells to topoisomerase poisons like camptothecin (Cpt) results from unrestrained end-joining of DNA ends at collapsed replication forks that is mediated by the non-homologo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de365d6acbb7a946d0b75b94181957c
https://doi.org/10.1016/j.dnarep.2020.102925
https://doi.org/10.1016/j.dnarep.2020.102925
Autor:
Jessica A. Neal, Katheryn Meek
DNA-PKcs deficiency has been studied in numerous animal models and cell culture systems. In previous studies of kinase inactivating mutations in cell culture systems, ablation of DNA-PK's catalytic activity results in a cell phenotype that is virtual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3573b75382a0630e1d62889c0b2eccc
https://europepmc.org/articles/PMC6312468/
https://europepmc.org/articles/PMC6312468/
Autor:
Joanna F. McGouran, Xinming Song, Zhengqiang Bao, Freddie C. Hamdy, Huahao Shen, Katheryn Meek, Annette L. Medhurst, Songmin Ying, Jessica A. Neal, Oliver Mortusewicz, Zhihui Chen, Benedikt M. Kessler, Thomas Helleday
Publikováno v:
Europe PubMed Central
A series of critical pathways are responsible for the detection, signaling, and restart of replication forks that encounter blocks during S-phase progression. Small base lesions may obstruct replication fork progression and processing, but the link b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b3ca85259eab8a50898020de5435ea
https://doi.org/10.1158/0008-5472.can-15-0608
https://doi.org/10.1158/0008-5472.can-15-0608
Autor:
Terrence P. McManus, Jessica A. Neal, Veronica M. Maher, J. Justin McCormick, Kristin McNally
Publikováno v:
DNA Repair. 7:597-604
Translesion synthesis (TLS) refers to mechanisms by which specialized DNA polymerases incorporate nucleotides opposite fork-blocking lesions and extend replication until standard replicative polymerases take over. The first eukaryotic TLS polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded4e4b428afe28575a88884c01d8c17
https://doi.org/10.1016/j.dnarep.2007.12.013
https://doi.org/10.1016/j.dnarep.2007.12.013
Publikováno v:
IEEE/ACM Joint Conference on Digital Libraries.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e81b63cc740cfc01e2a1e0941b2ab369
https://doi.org/10.1109/jcdl.2014.6970209
https://doi.org/10.1109/jcdl.2014.6970209