Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jessica A. Gorski"'
Publikováno v:
Cell Reports, Vol 37, Iss 1, Pp 109786- (2021)
Summary: Regulated insertion and removal of postsynaptic AMPA glutamate receptors (AMPARs) mediates hippocampal long-term potentiation (LTP) and long-term depression (LTD) synaptic plasticity underlying learning and memory. In Alzheimer’s disease
Externí odkaz:
https://doaj.org/article/23a0b8662e1f4cf7a49b25844d4df719
Autor:
Jonathan G. Murphy, Jennifer L. Sanderson, Jessica A. Gorski, John D. Scott, William A. Catterall, William A. Sather, Mark L. Dell’Acqua
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1577-1588 (2014)
L-type voltage-gated Ca2+ channels (LTCC) couple neuronal excitation to gene transcription. LTCC activity is elevated by the cyclic AMP (cAMP)-dependent protein kinase (PKA) and depressed by the Ca2+-dependent phosphatase calcineurin (CaN), and both
Externí odkaz:
https://doaj.org/article/b423bdfc8fac42d9851f3358a9fc2e92
Publikováno v:
Cell reports
Cell Reports, Vol 37, Iss 1, Pp 109786-(2021)
Cell Reports, Vol 37, Iss 1, Pp 109786-(2021)
SUMMARY Regulated insertion and removal of postsynaptic AMPA glutamate receptors (AMPARs) mediates hippocampal long-term potentiation (LTP) and long-term depression (LTD) synaptic plasticity underlying learning and memory. In Alzheimer’s disease β
Publikováno v:
Neuron. 89(5):1000-1015
Information processing in the brain requires multiple forms of synaptic plasticity that converge on regulation of NMDA and AMPA-type glutamate receptors (NMDAR, AMPAR), including long-term potentiation (LTP) and long-term depression (LTD) and homeost
Autor:
Jennifer L. Sanderson, Jonathan G. Murphy, Mark L. Dell'Acqua, William A. Catterall, Jessica A. Gorski, John D. Scott, William A. Sather
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1577-1588 (2014)
SummaryL-type voltage-gated Ca2+ channels (LTCC) couple neuronal excitation to gene transcription. LTCC activity is elevated by the cyclic AMP (cAMP)-dependent protein kinase (PKA) and depressed by the Ca2+-dependent phosphatase calcineurin (CaN), an
Autor:
Emily S. Gibson, Jennifer L. Sanderson, Jessica A. Gorski, Ronald K. Freund, Mark L. Dell'Acqua, Philip Lam, Wallace S. Chick
Publikováno v:
The Journal of Neuroscience. 32:15036-15052
AMPA receptors (AMPARs) are tetrameric ion channels assembled from GluA1–GluA4 subunits that mediate the majority of fast excitatory synaptic transmission in the brain. In the hippocampus, most synaptic AMPARs are composed of GluA1/2 or GluA2/3 wit
Autor:
Dipesh S. Amin, Alison J. Vigers, Tiffany Talley-Farnham, Baoji Xu, Jessica A. Gorski, Kevin R. Jones
Publikováno v:
Neuroscience. 212:1-18
Brain-derived neurotrophic factor (BDNF) plays important roles in the development, maintenance, and plasticity of the mammalian forebrain. These functions include regulation of neuronal maturation and survival, axonal and dendritic arborization, syna
Publikováno v:
Journal of Biological Chemistry. 284:16289-16297
Transition metals are essential enzyme cofactors that are required for a wide range of cellular processes. Paradoxically, whereas metal ions are essential for numerous cellular processes, they are also toxic. Therefore cells must tightly regulate met
Autor:
Anastassia Stoykova, Kevin R. Jones, Francesco Cecconi, Jessica A. Gorski, Tran Tuoc, Marcello D'Amelio, Peter Gruss, Silke Berger, Joachim Berger
Publikováno v:
Development
Monash University
Monash University
During development, Pax6 is expressed in a rostrolateral-high to caudomedial-low gradient in the majority of the cortical radial glial progenitors and endows them with neurogenic properties. Using a Cre/ loxP -based approach, we studied the effect of
Publikováno v:
Neuron. 89(5)
Information processing in the brain requires multiple forms of synaptic plasticity that converge on regulation of NMDA and AMPA-type glutamate receptors (NMDAR, AMPAR), including long-term potentiation (LTP) and long-term depression (LTD) and homeost