Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Jessica A. Burket"'
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 181 (2022)
Various ASD risk alleles have been associated with impairment of NMDA receptor activation (i.e., NMDA Receptor Hypofunction) and/or disturbance of the careful balance between activation mediated by GluN2B-subtype and GluN2A-subtype-containing NMDA re
Externí odkaz:
https://doaj.org/article/def7588c3f9c4538af5f333cbdc856c2
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1235 (2021)
Because of their abilities to catalyze generation of toxic free radical species, free concentrations of the redox reactive metals iron and copper are highly regulated. Importantly, desired neurobiological effects of these redox reactive metal cations
Externí odkaz:
https://doaj.org/article/f804146c52d743f8af3e5f22ecd604eb
Autor:
Stephen I, Deutsch, Jessica A, Burket
Publikováno v:
Medical Clinics of North America. 107:101-117
The BALB/c mouse displays hypersensitivity to behavioral effects of MK-801 (dizocilpine), a noncompetitive N-methyl-d-aspartic acid (NMDA) receptor "open-channel" blocker, and shows both no preference for an enclosed stimulus mouse over an inanimate
Autor:
Stephen I. Deutsch, Jessica A. Burket
Publikováno v:
Clinical Neuropharmacology. 44:138-140
Autism spectrum disorder can be associated with a variety of genetic findings. We report a heterozygous de novo missense variant of SCN2A, the gene coding a voltage-gated sodium ion channel enriched in the axon initial segment and nodes of Ranvier of
Autor:
Stephen I. Deutsch, Jessica A. Burket
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 90:142-160
NMDA receptors are widely distributed throughout the brain and major therapeutic challenges include targeting specific NMDA receptor subtypes while preserving spatial and temporal specificity during their activation. The NR2A-subunit containing NMDA
Autor:
Stephen I, Deutsch, Jessica A, Burket
Publikováno v:
Current topics in behavioral neurosciences. 45
Abnormalities of cholinergic nuclei, cholinergic projections, and cholinergic receptors, as well as abnormalities of growth factors involved in the maturation and maintenance of cholinergic neurons, have been described in postmortem brains of persons
Autor:
Stephen I. Deutsch, Jessica A. Burket
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 104
A growing expert consensus has emerged to guide prescribing behavior and monitoring of psychotropic medications in adults and older adults with intellectual disability (ID). However, there is little empirically-derived evidence to inform physician se
Autor:
Stephen I. Deutsch, Jessica A. Burket
Publikováno v:
Behavioral Pharmacology of the Cholinergic System ISBN: 9783030560126
Abnormalities of cholinergic nuclei, cholinergic projections, and cholinergic receptors, as well as abnormalities of growth factors involved in the maturation and maintenance of cholinergic neurons, have been described in postmortem brains of persons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f6ea0825e32ec942e5978a9386c04df
https://doi.org/10.1007/7854_2020_136
https://doi.org/10.1007/7854_2020_136
Autor:
Julia A. Sharp, Allison M. Rusk, Jessica A. Burket, Bronson A. Haynes, Jerrah C. Pickle, Stephen I. Deutsch
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 99
Stress reactivity and glucocorticoid signaling alterations are reported in mouse models of autism spectrum disorder (ASD). BALB/c mice display decreased locomotor activity in the presence of stimulus mice and spend less time exploring enclosed stimul
Publikováno v:
Personalized Medicine in Psychiatry. :100087
A 23 year old male diagnosed with autism spectrum disorder and treated with valproic acid presented with acute onset of hepatic failure; he died less than two months later. Laboratory studies led to a diagnosis of Wilson Disease. The case raised ques