Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jessica A. Bertout"'
Autor:
Kenneth R. Gundle, Karthik Rajasekaran, Jeffrey Houlton, Gary B. Deutsch, Thomas J. Ow, Robert G. Maki, John Pang, Cherie-Ann O. Nathan, Daniel Clayburgh, Jason G. Newman, Elyse Brinkmann, Michael J. Wagner, Seth M. Pollack, Matthew J. Thompson, Ryan J. Li, Vikas Mehta, Bradley A. Schiff, Barry I. Wenig, Paul L. Swiecicki, Alice L. Tang, Jessica L. Davis, Annemieke van Zante, Jessica A. Bertout, Wendy Jenkins, Atticus Turner, Marc Grenley, Connor Burns, Jason P. Frazier, Angela Merrell, Kimberly H. W. Sottero, Jonathan M. J. Derry, Kate C. Gillespie, Bre Mills, Richard A. Klinghoffer
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Drug development is systemically inefficient. Research and development costs for novel therapeutics average hundreds of millions to billions of dollars, with the overall likelihood of approval estimated to be as low as 6.7% for oncology
Externí odkaz:
https://doaj.org/article/df356ddd88154387999a5c867f337370
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Ethical review of both human and animal research is critical to ensuring that studies are conducted with due regard to the welfare and safety of enrolled subjects and to the integrity of the data. However, differences exist in laws, policies, and bes
Externí odkaz:
https://doaj.org/article/314b8450b11b446b92b586b19c49dd91
Autor:
Matthew T. Laurie, Jessica A. Bertout, Sean D. Taylor, Joshua N. Burton, Jay A. Shendure, Jason H. Bielas
Publikováno v:
BioTechniques, Vol 55, Iss 2, Pp 61-67 (2013)
Due to the high cost of failed runs and suboptimal data yields, quantification and determination of fragment size range are crucial steps in the library preparation process for massively parallel sequencing (or next-generation sequencing). Current li
Externí odkaz:
https://doaj.org/article/20f106af21d04134827a82ec7eebc0df
Autor:
Philippe J. R. Baneux, Jessica A. Bertout, John R. Middleton, William Stokes, Emily McCobb, Nathaniel Kollias, E. D. Murphey
Publikováno v:
Journal of the American Veterinary Medical Association. :1-6
To address the limitations of traditional IACUC review of clinical research studies involving client-owned animals, the AVMA issued a policy describing the use of a veterinary clinical studies committee (VCSC), analogous to an institutional review bo
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Table of microinjected drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc7b60dd4f612c1719b4b938f3f115c
https://doi.org/10.1158/1078-0432.22477539.v1
https://doi.org/10.1158/1078-0432.22477539.v1
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Microinjection of olaratumab does not inhibit PDGFRα, ERK, or S6 phosphorylation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e21e4c9b577eabda8261cdf9c16c3e0
https://doi.org/10.1158/1078-0432.22477542.v1
https://doi.org/10.1158/1078-0432.22477542.v1
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
All adverse events reported on the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c5adbf368fd28def73541f84f8cfd0
https://doi.org/10.1158/1078-0432.22477536.v1
https://doi.org/10.1158/1078-0432.22477536.v1
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b87dedf9125fa69357f4ec88861afd
https://doi.org/10.1158/1078-0432.22477527.v1
https://doi.org/10.1158/1078-0432.22477527.v1
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Distinct drug induced phenotypes and apoptotic responses specific to drug mechanism of action are seen at sites of CIVO microinjection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c94e647a6225c5c17f50ce28048d5d
https://doi.org/10.1158/1078-0432.22477554
https://doi.org/10.1158/1078-0432.22477554
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Purpose:A persistent issue in cancer drug development is the discordance between robust antitumor drug activity observed in laboratory models and the limited benefit frequently observed when patients are treated with the same agents in clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398ff92914248e7c61b819ae2261d244
https://doi.org/10.1158/1078-0432.c.6529692.v1
https://doi.org/10.1158/1078-0432.c.6529692.v1