Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jessica A Shugart"'
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64878 (2013)
The ability of memory CD8+ T cells to rapidly proliferate and acquire cytolytic activity is critical for protective immunity against intracellular pathogens. The signals that control this recall response remain unclear. We show that CD40L production
Externí odkaz:
https://doaj.org/article/9e127a608daa483ca0a9e921e463531d
Autor:
Keith S Bahjat, Nicole Meyer-Morse, Edward E Lemmens, Jessica A Shugart, Thomas W Dubensky, Dirk G Brockstedt, Daniel A Portnoy
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9, p e1000568 (2009)
Listeria monocytogenes is a facultative intracellular pathogen capable of inducing a robust cell-mediated immune response to sub-lethal infection. The capacity of L. monocytogenes to escape from the phagosome and enter the host cell cytosol is paramo
Externí odkaz:
https://doaj.org/article/24e54cb286f54a5a8a61c46bba2fe71d
Publikováno v:
PLoS Biology, Vol 2, Iss 11, p e366 (2004)
Major histocompatibility class I molecules display tens of thousands of peptides on the cell surface for immune surveillance by T cells. The peptide repertoire represents virtually all cellular translation products, and can thus reveal a foreign pres
Externí odkaz:
https://doaj.org/article/97b77d03a58d478c9ed2062b9836d2bd
Autor:
Shelly Bambina, Peter Lauer, Jessica A. Shugart, Lauren Zebertavage, Alejandro F Alice, Keith S. Bahjat, Kyra D. Zens, Michael J. Gough, Marka R. Crittenden, Bill Hanson
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209153 (2019)
PLoS ONE
PLoS ONE
Dysregulated signaling via the epidermal growth factor receptor (EGFR)-family is believed to contribute to the progression of a diverse array of cancers. The most common variant of EGFR is EGFRvIII, which results from a consistent and tumor-specific
Publikováno v:
Journal of Virology. 87:13927-13929
Long-distance host-independent virus dispersal is poorly understood, especially for viruses found in isolated ecosystems. To demonstrate a possible dispersal mechanism, we show that bacteriophage T4, archaeal virus Sulfolobus spindle-shaped virus Kam
Autor:
Edward E. Lemmens, Jessica A. Shugart, Daniel A. Portnoy, Keith S. Bahjat, Dirk G. Brockstedt, Nicole Meyer-Morse, Thomas W. Dubensky
Publikováno v:
PLoS pathogens, vol 5, iss 9
PLoS Pathogens
PLoS Pathogens, Vol 5, Iss 9, p e1000568 (2009)
PLoS Pathogens
PLoS Pathogens, Vol 5, Iss 9, p e1000568 (2009)
Listeria monocytogenes is a facultative intracellular pathogen capable of inducing a robust cell-mediated immune response to sub-lethal infection. The capacity of L. monocytogenes to escape from the phagosome and enter the host cell cytosol is paramo
Autor:
Jessica Alis Shugart, Nilabh Shastri
Publikováno v:
The Journal of Immunology. 178:S12-S12
Prior to their appearance on the cell surface where they are presented by MHC I molecules to T cells, antigenic peptides are created by a complex array of intracellular processing events. Using conventional T cell assays, only the final peptide can b