Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jessica A Pilsworth"'
Autor:
Jessica A Pilsworth, Dawn R Cochrane, Samantha J Neilson, Bahar H Moussavi, Daniel Lai, Aslı D Munzur, Janine Senz, Yi Kan Wang, Sina Zareian, Ali Bashashati, Adele Wong, Jacqueline Keul, Annette Staebler, Hannah S vanMeurs, Hugo M Horlings, Stefan Kommoss, Friedrich Kommoss, Esther Oliva, Anniina EM Färkkilä, Blake Gilks, David G Huntsman
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 3, Pp 243-252 (2021)
Abstract Adult‐type granulosa cell tumors (aGCTs) account for 90% of malignant ovarian sex cord‐stromal tumors and 2–5% of all ovarian cancers. These tumors are usually diagnosed at an early stage and are treated with surgery. However, one‐th
Externí odkaz:
https://doaj.org/article/119bf70995b744d0addb4d02ce2fc2fa
Autor:
Puya Seid-Karbasi, Xin C Ye, Allen W Zhang, Nicole Gladish, Suzanne Y S Cheng, Katharina Rothe, Jessica A Pilsworth, Min A Kang, Natalie Doolittle, Xiaoyan Jiang, Peter C Stirling, Wyeth W Wasserman
Publikováno v:
PLoS Biology, Vol 15, Iss 3, p e2001192 (2017)
Student creation of educational materials has the capacity both to enhance learning and to decrease costs. Three successive honors-style classes of undergraduate students in a cancer genetics class worked with a new software system, CuboCube, to crea
Externí odkaz:
https://doaj.org/article/0f991d7c342c4fe09f41abcc77b6c2de
Autor:
Jessica A. Pilsworth, Mikko Anttonen, Dawn R. Cochrane, Samantha J. Neilson, Reiner A. Veitia, Markku Heikinheimo, David G. Huntsman, Anne-Laure Todeschini, Daniel Lai
Publikováno v:
The Journal of Pathology. 255:225-231
A recurrent mutation in FOXL2 (c.402C>G; p.C134W) is present in over 95% of adult-type granulosa cell tumours (AGCTs). In contrast, various loss-of-function mutations in FOXL2 lead to the development of blepharophimosis, ptosis, and epicanthus invers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c580b7f123f3ec49a578701d897d3e
https://doi.org/10.1002/path.5771
https://doi.org/10.1002/path.5771
Publikováno v:
EMBO J
The EMBO Journal
The EMBO Journal
[Image: see text]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29f463de86a0602b2bba9b152f77d69
https://doi.org/10.15252/embj.2020107517
https://doi.org/10.15252/embj.2020107517
Autor:
Readman Chiu, Sergio Martinez-Høyer, Marco A. Marra, Richard A. Moore, Martin Jädersten, T. Roderick Docking, Andrew J. Mungall, Linda Chang, Gerben Duns, Aly Karsan, Karen Mungall, Donna E. Hogge, Ka Ming Nip, Ryan J. Stubbins, Lucas Swanson, Samantha Mar, Inanc Birol, Angela Mo, Jessica A. Pilsworth, Xuan Wang, Jihong Jiang, Simon K. Chan, Steven J.M. Jones, Jeremy Parker
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
As more clinically-relevant genomic features of myeloid malignancies are revealed, it has become clear that targeted clinical genetic testing is inadequate for risk stratification. Here, we develop and validate a clinical transcriptome-based assay fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4b290a3a79622ea4678fb99498fc45
https://doi.org/10.1038/s41467-021-22625-y
https://doi.org/10.1038/s41467-021-22625-y
Autor:
Hannah S. van Meurs, Hugo M. Horlings, Bahar H. Moussavi, Daniel Lai, Adele Wong, Stefan Kommoss, Anniina Färkkilä, Asli D. Munzur, Esther Oliva, Friedrich Kommoss, Ali Bashashati, Janine Senz, Jessica A. Pilsworth, Sina Zareian, Yi Kan Wang, Jacqueline Keul, Dawn R. Cochrane, Blake Gilks, David G. Huntsman, Samantha J. Neilson, Annette Staebler
Publikováno v:
The Journal of Pathology: Clinical Research
journal of pathology. Clinical research, 7(3), 243-252. Wiley-Blackwell Publishing Ltd
The Journal of Pathology: Clinical Research, Vol 7, Iss 3, Pp 243-252 (2021)
journal of pathology. Clinical research, 7(3), 243-252. Wiley-Blackwell Publishing Ltd
The Journal of Pathology: Clinical Research, Vol 7, Iss 3, Pp 243-252 (2021)
Adult-type granulosa cell tumors (aGCTs) account for 90% of malignant ovarian sex cord-stromal tumors and 2-5% of all ovarian cancers. These tumors are usually diagnosed at an early stage and are treated with surgery. However, one-third of patients r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec97b44fb30d3bf7a053aaec9a27226d
https://pubmed.ncbi.nlm.nih.gov/33428330
https://pubmed.ncbi.nlm.nih.gov/33428330
Autor:
Claudia Iavarone, Roger A. Greenberg, Kaiyang Zhang, Douglas A. Levine, Josephine Walton, Brad H. Nelson, Kunle Odunsi, Francesmary Modugno, David R. Spriggs, Robert L. Coleman, Monicka Wielgos-Bonvallet, Zhen Lu, Darren Ennis, Robert P. Edwards, Ronny Drapkin, Ie Ming Shih, David G. Huntsman, Joan S. Brugge, Jessica A. Pilsworth, Daniel J. Powell, Kevin M. Elias, Andrew Futreal, Anil K. Sood, Lee Zou, Ursula A. Matulonis, Ahmed Ashour Ahmed, Robert Rottapel, Kai Doberstein, Giulio Draetta, David M. Gershenson, David D.L. Bowtell, James D. Brenton, Mark A. Eckert, Christopher J. Lord, Ernst Lengyel, Elise C. Kohn, Jennifer X Ji, Frances R. Balkwill, Gordon B. Mills, Robert C. Bast, Adaobi E. Amobi, Li Shen, Rugang Zhang
Publikováno v:
Cancer
Substantial progress has been made in understanding ovarian cancer at the molecular and cellular level. Significant improvement in 5-year survival has been achieved through cytoreductive surgery, combination platinum-based chemotherapy, and more effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397dbdd63bbc770344c9cc5667559597
https://pubmed.ncbi.nlm.nih.gov/30835824
https://pubmed.ncbi.nlm.nih.gov/30835824
Autor:
Sara Y. Brucker, David G. Huntsman, Friedrich Kommoss, Winnie Yang, Dawn R. Cochrane, Adele Wong, Hannah S. van Meurs, Anniina Färkkilä, Jacqueline Keul, Satoshi Yanagida, Annette Staebler, Duncan M. Baird, Stefan Kommoss, Zhouchunyang Xia, Hugo M. Horlings, Jamie L. P. Lim, Florin-Andrei Taran, Ali Bashashati, Geraldine Aubert, C. Blake Gilks, Esther Oliva, Bernhard K. Krämer, Yi Kan Wang, Jessica A. Pilsworth, Sohrab P. Shah, Kevin Norris
Publikováno v:
Modern pathology, 31(7), 1107-1115. Nature Publishing Group
The telomerase reverse transcriptase (TERT) gene is highly expressed in stem cells and silenced upon differentiation. Cancer cells can attain immortality by activating TERT to maintain telomere length and telomerase activity, which is a crucial step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aad2472af6747b37e86b909e75ad909
https://pure.amc.nl/en/publications/tert-promoter-mutation-in-adult-granulosa-cell-tumor-of-the-ovary(3afff303-563b-4be8-860a-59f005e03a59).html
https://pure.amc.nl/en/publications/tert-promoter-mutation-in-adult-granulosa-cell-tumor-of-the-ovary(3afff303-563b-4be8-860a-59f005e03a59).html
Autor:
Katharina Rothe, Natalie Doolittle, Xin C. Ye, Nicole Gladish, Allen W. Zhang, Xiaoyan Jiang, Puya Seid-Karbasi, Suzanne Y. S. Cheng, Wyeth W. Wasserman, Peter C. Stirling, Min A. Kang, Jessica A. Pilsworth
Publikováno v:
PLoS Biology, Vol 15, Iss 3, p e2001192 (2017)
PLoS Biology
PLoS Biology
Student creation of educational materials has the capacity both to enhance learning and to decrease costs. Three successive honors-style classes of undergraduate students in a cancer genetics class worked with a new software system, CuboCube, to crea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5891b26a67d54d48cde8b347984cf0
https://doaj.org/article/0f991d7c342c4fe09f41abcc77b6c2de
https://doaj.org/article/0f991d7c342c4fe09f41abcc77b6c2de
Autor:
Jacqueline Keul, Ali Bashashati, Samantha J. Neilson, Florin-Andrei Taran, Sara Y. Brucker, Yi Kan Wang, C. Blake Gilks, Esther Oliva, Dawn R. Cochrane, Hugo M. Horlings, David G. Huntsman, Anniina Färkkilä, Annette Staebler, Satoshi Yanagida, Hannah S. van Meurs, Stefan Kommoss, Friedrich Kommoss, Bahar H. Moussavi, Daniel Lai, Janine Senz, Jessica A. Pilsworth, Adele Wong, Bernhard K. Krämer, Sohrab P. Shah
Publikováno v:
Clinical Cancer Research. 25:GMM-047
BACKGROUND: Adult granulosa cell tumors (AGCT) represent 3-5% of all ovarian cancers. These tumors are characterized by their slow growth and usually occur in postmenopausal women with a median age of diagnosis of 50 to 54 years. The majority of pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d94bd8b13582b08447ca310ce8e3713
https://doi.org/10.1158/1557-3265.ovcasymp18-gmm-047
https://doi.org/10.1158/1557-3265.ovcasymp18-gmm-047