Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jessica A Hess"'
Autor:
Lauren E Springer, John B Patton, Tingting Zhan, Arnold B Rabson, Hsin-Ching Lin, Tim Manser, James B Lok, Jessica A Hess, David Abraham
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009559 (2021)
Viral and parasitic coinfections are known to lead to both enhanced disease progression and altered disease states. HTLV-1 and Strongyloides stercoralis are co-endemic throughout much of their worldwide ranges resulting in a significant incidence of
Externí odkaz:
https://doaj.org/article/b5fb2f03c28b4784a7c66e02afdad02a
Autor:
Parakkal Jovvian George, Jessica A Hess, Sonia Jain, John B Patton, Tingting Zhan, Nancy Tricoche, Bin Zhan, Maria Elena Bottazzi, Peter J Hotez, David Abraham, Sara Lustigman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 9, p e0007730 (2019)
BACKGROUND:The current strategy for the elimination of onchocerciasis is based on annual or bi-annual mass drug administration with ivermectin. However, due to several limiting factors there is a growing concern that elimination of onchocerciasis can
Externí odkaz:
https://doaj.org/article/6f950833207848678f3ab4de08187bb6
Autor:
John B Patton, Sasisekhar Bennuru, Mark L Eberhard, Jessica A Hess, April Torigian, Sara Lustigman, Thomas B Nutman, David Abraham
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0006977 (2018)
BackgroundThe study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the development of adult parasites have
Externí odkaz:
https://doaj.org/article/d5eefc01f5184522a2b2fc4f3dadff49
Autor:
Jessica A Hess, Bin Zhan, April R Torigian, John B Patton, Nikolai Petrovsky, Tingting Zhan, Maria Elena Bottazzi, Peter J Hotez, Thomas R Klei, Sara Lustigman, David Abraham
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 7, p e0004797 (2016)
BACKGROUND:In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. A vaccine aga
Externí odkaz:
https://doaj.org/article/1b8bd271a8604e77913fb5d8759815b5
Autor:
Abraham, Nathan M. Ryan, Jessica A. Hess, Erica J. Robertson, Nancy Tricoche, Cheri Turner, Jenn Davis, Nikolai Petrovsky, Melissa Ferguson, William J. Rinaldi, Valerie M. Wong, Ayako Shimada, Bin Zhan, Maria Elena Bottazzi, Benjamin L. Makepeace, Sean A. Gray, Darrick Carter, Sara Lustigman, David
Publikováno v:
Vaccines; Volume 11; Issue 7; Pages: 1212
Onchocerciasis remains a debilitating neglected tropical disease. Due to the many challenges of current control methods, an effective vaccine against the causative agent Onchocerca volvulus is urgently needed. Mice and cynomolgus macaque non-human pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::843945a94f133a7cc2da699aada5aaaa
Autor:
Jessica A. Hess, Mark L. Eberhard, Marcelo Segura-Lepe, Kathrin Grundner-Culemann, Barbara Kracher, Jeffrey Shryock, John Harrington, David Abraham
Publikováno v:
Scientific Reports. 13
Heartworm disease, caused by Dirofilaria immitis, remains a significant threat to canines and felines. The development of parasites resistant to macrocyclic lactones (ML) has created a significant challenge to the control of the infection. The goal o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c60a587b817ace94a32c8f45578a34a8
https://doi.org/10.1038/s41598-023-27537-z
https://doi.org/10.1038/s41598-023-27537-z
Autor:
Jessica D. Hess, Luca H. Macias, Denisse A. Gutierrez, Karla Moran-Santibanez, Lisett Contreras, Stephanie Medina, Paulina J. Villanueva, Robert A. Kirken, Armando Varela-Ramirez, Manuel L. Penichet, Renato J. Aguilera
Publikováno v:
Biology; Volume 11; Issue 6; Pages: 930
In recent years, the thienopyrazole moiety has emerged as a pharmacologically active scaffold with antitumoral and kinase inhibitory activity. In this study, high-throughput screening of 2000 small molecules obtained from the ChemBridge DIVERset libr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e96cb61954c5544c7f84a3bb550c1e
Autor:
Nathan M, Ryan, Jessica A, Hess, Fernando Pardo-Manuel, de Villena, Benjamin E, Leiby, Ayako, Shimada, Lei, Yu, Amir, Yarmahmoodi, Nikolai, Petrovsky, Bin, Zhan, Maria Elena, Bottazzi, Benjamin L, Makepeace, Sara, Lustigman, David, Abraham
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
NPJ VACCINES
NPJ Vaccines
NPJ VACCINES
NPJ Vaccines
This study tests the hypothesis that an Onchocerca volvulus vaccine, consisting of two recombinant antigens (Ov-103 and Ov-RAL-2) formulated with the combination-adjuvant Advax-2, can induce protective immunity in genetically diverse Collaborative Cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b1214251781c51c6a49732cf4901308f
https://doaj.org/article/81bbb94a2d7b4f9fa3b415ead7d31ec9
https://doaj.org/article/81bbb94a2d7b4f9fa3b415ead7d31ec9
Autor:
Jessica A. Hess, John Graham-Brown, Sean A. Gray, Sara Lustigman, Benjamin L. Makepeace, David Abraham, Darrick Carter
Publikováno v:
EXPERT REVIEW OF VACCINES
INTRODUCTION Human onchocerciasis caused by the filarial nematode parasite Onchocerca volvulus remains a major cause of debilitating disease infecting millions primarily in Sub-Saharan Africa. The development of a prophylactic vaccine, along with mas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8326c6b6146509c2ae602af46b7ff58b
http://livrepository.liverpool.ac.uk/3137904/1/Abraham-2021.pdf
http://livrepository.liverpool.ac.uk/3137904/1/Abraham-2021.pdf
Autor:
Jessica D. Hess, Mahesh K. Lakshman, Padmanava Pradhan, Robert Snoeck, Renato J. Aguilera, Dominique Schols, Tashrique A. Khandaker, Graciela Andrei
Publikováno v:
European Journal of Organic Chemistry
1,4‐Triazolyl combretacoumarins have been prepared by linking the trimethoxyarene unit of combretastatin A4 with coumarins, via a 1,2,3‐triazole. For this, 4‐azidocoumarins were accessed by a sequential two‐step, one‐pot reaction of 4‐hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397abe675193e8985ea2b9d9f9d7d589
https://doi.org/10.1002/ejoc.201900569
https://doi.org/10.1002/ejoc.201900569