Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Jessica A Dominguez Rieg,"'
Autor:
Linto Thomas, Lashodya V. Dissanayake, Maryam Tahmasbi, Alexander Staruschenko, Sima Al-Masri, Jessica A. Dominguez Rieg, Timo Rieg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Vitamin D3 is clinically used for the treatment of vitamin D3 deficiency or osteoporosis, partially because of its role in regulating phosphate (Pi) and calcium (Ca2+) homeostasis. The renal sodium-phosphate cotransporter 2a (Npt2a) plays an
Externí odkaz:
https://doaj.org/article/5bacf6cc89e742b9b6f470f6ef8bb7fa
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
In the intestine, the Na+/H+ exchanger 3 (NHE3) plays a critical role for Na+ and fluid absorption. NHE3 deficiency predisposes patients to inflammatory bowel disease (IBD). In mice, selective deletion of intestinal NHE3 causes various local and syst
Externí odkaz:
https://doaj.org/article/58b30e40531a4f348b1a38f9cc394c3f
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244251 (2020)
The connexin 37 (Cx37) channel is clustered at gap junctions between cells in the renal vasculature or the renal tubule where it is abundant in basolateral cell interdigitations and infoldings of epithelial cells in the proximal tubule, thick ascendi
Externí odkaz:
https://doaj.org/article/ca1b54c5436741a48940a1818d460b7d
Autor:
Jessica A Dominguez Rieg,
Publikováno v:
Revista Cubana de Investigaciones Biomédicas, Vol 38, Iss 5 (2020)
Introduction: Teaching students how to think logically about disease processes is essential to increasing retention of their physiology knowledge base and developing effective clinical reasoning skills. At the University Of South Florida Morsani Coll
Externí odkaz:
https://doaj.org/article/4a1a3c0620e5420c88d5f30618b85c0d
Publikováno v:
Revista Cubana de Investigaciones Biomédicas, Vol 38, Iss 5 (2020)
Introduction: Hyperphosphatemia is common in patients with chronic kidney disease and associated with increased mortality. Oral phosphate binders and dietary phosphate restriction are the current management protocols for patients with hyperphosphatem
Externí odkaz:
https://doaj.org/article/dd428a15acb743f29849df37913b355d
Publikováno v:
Xue, J, Thomas, L, Dominguez Rieg, J A, Fenton, R A & Rieg, T 2022, ' NHE3 in the thick ascending limb is required for sustained but not acute furosemide-induced urinary acidification ', American journal of physiology. Renal physiology, vol. 323, no. 2, pp. F141-F155 . https://doi.org/10.1152/ajprenal.00013.2022
The Na +/H + exchanger isoform 3 (NHE3) facilitates Na + reabsorption and H + secretion by the kidneys. Despite stronger NHE3 abundance in the thick ascending limb (TAL) compared to the S1 and S2 segments of the proximal tubule, the role of NHE3 in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f719b2cd5b52a1f14da21602577a80d
https://doi.org/10.1152/ajprenal.00013.2022
https://doi.org/10.1152/ajprenal.00013.2022
Publikováno v:
Current Opinion in Nephrology & Hypertension. 31:486-492
Targeting sodium phosphate cotransporter 2a (Npt2a) offers a novel strategy for treating hyperphosphatemia in chronic kidney disease (CKD). Here we review recent studies on the efficacy of Npt2a inhibition, its plasma phosphate (Pi)-lowering effects,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31394a2f60779abd545fa033c9da289
https://doi.org/10.1097/mnh.0000000000000828
https://doi.org/10.1097/mnh.0000000000000828
Publikováno v:
Physiology. 38
1,25(OH)2 vitamin D3 (Vit-D3) is a hormone that is formed by the coordinated actions of the skin and kidneys and is involved in the regulation of Ca2+ and phosphate (Pi) homeostasis. Of note, the regulation of these minerals is complex and involves o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97dd83e4fafff19f89de59ebb01b458a
https://doi.org/10.1152/physiol.2023.38.s1.5734204
https://doi.org/10.1152/physiol.2023.38.s1.5734204
Publikováno v:
Xue, J, Thomas, L, Fenton, R A, Dominguez Rieg, J A & Rieg, T 2022, ' Generation and characterization of thick ascending limb specific knockout of NHE3 mouse model ', The FASEB Journal, vol. 36, no. S1 . https://doi.org/10.1096/fasebj.2022.36.S1.R4942
The Na+/H+ exchanger 3 (NHE3) mediates Na+ (re)absorption in the intestine and the kidney, thereby playing a key role in fluid homeostasis and blood pressure (BP) regulation. NHE3 is expressed in the luminal membrane of the renal proximal tubule, whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f007dbad95f98209cfb2b6df7723e9d7
https://pure.au.dk/portal/da/publications/generation-and-characterization-of-thick-ascending-limb-specific-knockout-of-nhe3-mouse-model(2b440184-3e86-418c-8b0c-59e651cad0cb).html
https://pure.au.dk/portal/da/publications/generation-and-characterization-of-thick-ascending-limb-specific-knockout-of-nhe3-mouse-model(2b440184-3e86-418c-8b0c-59e651cad0cb).html
Autor:
Linto Thomas, Jianxiang Xue, Sathish K. Murali, Moshe Levy, Robert A. Fenton, Jessica A. Dominguez Rieg, Timo Rieg
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c9bb4e6c2cb3aeff0251d4c81f64ab
https://doi.org/10.1096/fasebj.2022.36.s1.r4966
https://doi.org/10.1096/fasebj.2022.36.s1.r4966