Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jessica A, Talamas"'
Autor:
Chao Dai, Jonathan P. Rennhack, Taylor E. Arnoff, Maneesha Thaker, Scott T. Younger, John G. Doench, August Yue Huang, Annan Yang, Andrew J. Aguirre, Belinda Wang, Evan Mun, Joyce T. O’Connell, Ying Huang, Katherine Labella, Jessica A. Talamas, Ji Li, Nina Ilic, Justin Hwang, Andrew L. Hong, Andrew O. Giacomelli, Ole Gjoerup, David E. Root, William C. Hahn
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109443- (2021)
Summary: Metastasis is a complex and poorly understood process. In pancreatic cancer, loss of the transforming growth factor (TGF)-β/BMP effector SMAD4 is correlated with changes in altered histopathological transitions, metastatic disease, and poor
Externí odkaz:
https://doaj.org/article/576815dfcfd2415692f51077629b4730
Autor:
Filemon S. Dela Cruz, Hiroyuki Yoda, Calvin J. Kuo, William C. Hahn, Kelly Kersten, Olivier Gevaert, Michitaka Nakano, Bruce K. Hua, Yohannes Tsehay, Han Liang, Yun Rose Li, Taofeek K. Owonikoko, Yunqi Yan, Katherine N. Liu, Stephen E. Kurtz, Andrew J. Ewald, Gordon B. Mills, Matthew Dunworth, Yuhao Wang, Eloise M. Grasset, Joseph Estabrook, Nicola Long, Vasanthi S. Viswanathan, Bridget Robinson, Shubhroz Gill, Matthew C. Perrone, Ken Chen, Suresh S. Ramalingam, Robert T. Manguso, Asmita Bhattacharya, Andrea Califano, Wei Zhou, Yuhong Du, Elodie Henriet, Jordana Brown, Francisca Vazquez, Michael T. McManus, Manisha Warrier, Gabriel Eades, Anuja Sathe, Yilong Zou, Yoko Kosaka, Matthew A. Reyna, Theodore P. Braun, Daniela S. Gerhard, Matthew F. Krummel, Allan Balmain, Tamilla Nechiporuk, Hanlee P. Ji, Quin Morrow, Emek Demir, Pablo Tamayo, Jessica Minnier, Michael C. Bassik, Kevin Watanabe-Smith, Xiulei Mo, Qi-Wen Fan, Nicole Nasholm, Sagar Lonial, Stuart L. Schreiber, Brent R. Stockwell, Nina K. Serwas, Sourav Bandyopadhyay, Brian J. Druker, Christina Curtis, Yuan-Hung Lo, Olga Nikolova, Qiankun Niu, Veena Padmanaban, Yuchen Ge, Cristina E. Tognon, Anupriya Agarwal, Christopher J. Kemp, Kremena Karagyozova, Haian Fu, Trevor Bivona, Dan Georgess, Nidhi Sahni, Stefan Oberlin, Issac S. Chan, Michael G. Lerner, Matt Hangauer, Jennifer Saultz, Wing Hing Wong, Ilya Shmulevich, Christin Schmidt, Yasir Suhail, Andy Kaempf, Alan Ashworth, Saumya R. Bollam, Tanaz Sharifnia, Jesse S. Boehm, Kasper Karlsson, Carlos S. Moreno, Neil Tay, Michael Grzadkowski, Kevin C. Brennan, Subhashini Jagu, Elizabeth M. Swisher, Ben Deneen, Jessica A. Talamas, Amber R. Smith, Joel S. Bader, Vlado Dančík, Andrew L. Kung, William A. Weiss, Hildur Knutsdottir, Tania Q. Vu, Lee Cooper, Kanako Yuki, Wei-Ching Chen, Bridget K. Wagner, Evan F. Lind, Josh Dempster, Marie Menard, Carla Grandori, Andrey A. Ivanov, William Kim, Jeffrey W. Tyner, Jonathan S. Weissman, Thomas Jacob, Paul A. Clemons, Jitong Cai, Kaitlyn Spees, Dan S. Kaufman
Publikováno v:
Cell, vol 184, iss 5
Cell
Cell
The characterization of cancer genomes has provided insight into somatically altered genes across tumors, transformed our understanding of cancer biology, and enabled tailoring of therapeutic strategies. However, the function of most cancer alleles r
Autor:
Maya eCapelson, Jessica A Talamas
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
The eukaryotic cell nucleus houses an organism’s genome and is the location within the cell, where all signaling-induced and development-driven gene expression programs are ultimately specified. The genome is enclosed and separated from the cytopla
Externí odkaz:
https://doaj.org/article/cdb086aa4b2247fcac3aed8f21a409d8
Autor:
Miju Kim, Seav Huong Ly, Yingtian Xie, Gina N. Duronio, Dane Ford-Roshon, Justin H. Hwang, Rita Sulahian, Jonathan P. Rennhack, Jonathan So, Ole Gjoerup, Jessica A. Talamas, Maximilien Grandclaudon, Henry W. Long, John G. Doench, Nilay S. Sethi, Marios Giannakis, William C. Hahn
Publikováno v:
Dev Cell
The transcriptional co-activator YAP1 oncogene is the downstream effector of the Hippo pathway, which regulates tissue homeostasis, organ size, regeneration, and tumorigenesis. Multiple cancers are dependent on sustained expression of YAP1 for cell p
Autor:
Joyce T. O’Connell, Andrew J. Aguirre, Nina Ilic, John G. Doench, Ole Gjoerup, Ying Huang, Jonathan P. Rennhack, Andrew L. Hong, Andrew O. Giacomelli, Belinda Wang, William C. Hahn, Katherine Labella, Jessica A. Talamas, Annan Yang, Scott T. Younger, Evan Mun, Taylor E. Arnoff, Justin H. Hwang, Chao Dai, Ji Li, August Yue Huang, David E. Root, Maneesha Thaker
Publikováno v:
Cell reports
Cell Reports, Vol 36, Iss 4, Pp 109443-(2021)
Cell Reports, Vol 36, Iss 4, Pp 109443-(2021)
SUMMARY Metastasis is a complex and poorly understood process. In pancreatic cancer, loss of the transforming growth factor (TGF)-β/BMP effector SMAD4 is correlated with changes in altered histopathological transitions, metastatic disease, and poor
Autor:
Maya Capelson, Rajan Jain, Parisha P. Shah, Jessica A. Talamas, Yemin Lan, Ashley A. Duke, Pau Pascual-Garcia, Alejandro Gozalo, Eric F. Joyce, Son C. Nguyen
Publikováno v:
Mol Cell
Interactions between the genome and the nuclear pore complex (NPC) have been implicated in multiple gene regulatory processes, but the underlying logic of these interactions remains poorly defined. Here, we report high-resolution chromatin binding ma
Autor:
Jessica A. Talamas, Martin W. Hetzer
Publikováno v:
The Journal of Cell Biology
POM121 and Sun1, but not the Nup107–160 complex, are required for fusion of the inner and outer nuclear membrane during nuclear pore assembly in interphase of the cell cycle.
Nuclear pore complexes (NPCs) assemble at the end of mitosis during
Nuclear pore complexes (NPCs) assemble at the end of mitosis during
Autor:
Jessica A. Talamas, Maya Capelson
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
Frontiers in Genetics
Frontiers in Genetics
The eukaryotic cell nucleus houses an organism’s genome and is the location within the cell, where all signaling-induced and development-driven gene expression programs are ultimately specified. The genome is enclosed and separated from the cytopla
Autor:
Chad, Nusbaum, Michael C, Zody, Mark L, Borowsky, Michael, Kamal, Chinnappa D, Kodira, Todd D, Taylor, Charles A, Whittaker, Jean L, Chang, Christina A, Cuomo, Ken, Dewar, Michael G, FitzGerald, Xiaoping, Yang, Amr, Abouelleil, Nicole R, Allen, Scott, Anderson, Toby, Bloom, Boris, Bugalter, Jonathan, Butler, April, Cook, David, DeCaprio, Reinhard, Engels, Manuel, Garber, Andreas, Gnirke, Nabil, Hafez, Jennifer L, Hall, Catherine Hosage, Norman, Takehiko, Itoh, David B, Jaffe, Yoko, Kuroki, Jessica, Lehoczky, Annie, Lui, Pendexter, Macdonald, Evan, Mauceli, Tarjei S, Mikkelsen, Jerome W, Naylor, Robert, Nicol, Cindy, Nguyen, Hideki, Noguchi, Sinéad B, O'Leary, Keith, O'Neill, Bruno, Piqani, Cherylyn L, Smith, Jessica A, Talamas, Kerri, Topham, Yasushi, Totoki, Atsushi, Toyoda, Hester M, Wain, Sarah K, Young, Qiandong, Zeng, Andrew R, Zimmer, Asao, Fujiyama, Masahira, Hattori, Bruce W, Birren, Yoshiyuki, Sakaki, Eric S, Lander
Publikováno v:
Nature. 437:551-555
Chromosome 18 appears to have the lowest gene density of any human chromosome and is one of only three chromosomes for which trisomic individuals survive to term. There are also a number of genetic disorders stemming from chromosome 18 trisomy and an
Autor:
Maya Capelson, Kyoung J. Won, Jessica A. Talamas, Yemin Lan, Brian M. Debo, Jennifer R. Aleman, Pau Pascual-Garcia, Nha Nguyen
Publikováno v:
Molecular Cell. 66:63-76.e6
Nuclear pore complex components (Nups) have been implicated in transcriptional regulation, yet what regulatory steps are controlled by metazoan Nups remains unclear. We identified the presence of multiple Nups at promoters, enhancers, and insulators