Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jessica, Pruessmeyer"'
Autor:
Christopher Nimsky, Jessica Pruessmeyer, Peter J B Anderson, Marion Roessler, Catharina Conrad, Jane E. Preston, Andreas Ludwig, Rainer Ritz, Axel Pagenstecher, Roger D. Kamm, Malena Götte, Jörg W. Bartsch, Uwe Schlomann, Ran Li, Barbara Carl
Publikováno v:
International Journal of Cancer. 142:779-791
Metastatic breast cancer affects long-term survival and is a major cause of cancer death for women worldwide. The Metalloprotease-Disintegrin ADAM8 promotes breast cancer development and brain metastasis in a mouse breast cancer model. Here, abundant
Autor:
Aaron Babendreyer, Andreas Ludwig, Julian Schumacher, Franz M. Hess, Sandra Fellendorf, Anke Seifert, Joerg W. Bartsch, Jessica Pruessmeyer, Daniela Dreymueller
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 313:L602-L614
Alveolar leukocyte recruitment is a hallmark of acute lung inflammation and involves transmigration of leukocytes through endothelial and epithelial layers. The disintegrin and metalloproteinase (ADAM) 8 is expressed on human isolated leukocytic cell
Stimulated release and functional activity of surface expressed metalloproteinase ADAM17 in exosomes
Autor:
Esther Groth, Inken Lorenzen, Aaron Babendreyer, Joachim Grötzinger, Tobias Pasqualon, Jessica Pruessmeyer, Daniela Dreymueller, Andreas Ludwig, Didier Cataldo, Julian Schumacher, Shigeki Higashiyama
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1863:2795-2808
By mediating proteolytic shedding on the cell surface the disintegrin and metalloproteinases ADAM10 and ADAM17 function as critical regulators of growth factors, cytokines and adhesion molecules. We here report that stimulation of lung epithelial A54
Autor:
Jessica Pruessmeyer, Holger Jahr, Bernd Denecke, Jürgen Bernhagen, Sabine Groening, Hongqi Lue, Andreas Ludwig, Tobias Pasqualon
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1863(4):717-726
Surface expressed proteoglycans mediate the binding of cytokines and chemokines to the cell surface and promote migration of various tumor cell types including epithelial tumor cells. We here demonstrate that binding of the chemokine-like inflammator
Autor:
Catharina, Conrad, Malena, Götte, Uwe, Schlomann, Marion, Roessler, Axel, Pagenstecher, Peter, Anderson, Jane, Preston, Jessica, Pruessmeyer, Andreas, Ludwig, Ran, Li, Roger D, Kamm, Rainer, Ritz, Barbara, Carl, Christopher, Nimsky, Jörg W, Bartsch
Publikováno v:
International journal of cancer. 142(4)
Metastatic breast cancer affects long-term survival and is a major cause of cancer death for women worldwide. The Metalloprotease-Disintegrin ADAM8 promotes breast cancer development and brain metastasis in a mouse breast cancer model. Here, abundant
Autor:
Jos Kollert, Tobias Pasqualon, Franz M. Hess, Paul Saftig, Andreas Ludwig, Stella Nyamoya, Stefan Uhlig, Emiel P. C. van der Vorst, Marjo M. P. C. Donners, Henriette Alert, Daniela Dreymueller, Esther Groth, Christian Martin, Jessica Pruessmeyer, Nicole Schwarz
Publikováno v:
Blood, 123(26), 4077-4088. The American Society of Hematology
Inflammation is a key process in various diseases, characterized by leukocyte recruitment to the inflammatory site. This study investigates the role of a disintegrin and a metalloproteinase (ADAM) 10 and ADAM17 for leukocyte migration in vitro and in
Publikováno v:
European Journal of Cell Biology. 91:472-485
Within the vasculature the disintegrins and metalloproteinases (ADAMs) 8, 9, 10, 12, 15, 17, 19, 28 and 33 are expressed on endothelial cells, smooth muscle cells and on leukocytes. As surface-expressed proteases they mediate cleavage of vascular sur
Autor:
Daniela Dreymueller, Franz M. Hess, Keisuke Horiuchi, Andreas Ludwig, Christian Martin, Stefan Uhlig, Tanja Kogel, Jessica Pruessmeyer
Publikováno v:
EMBO Molecular Medicine
Acute lung injury (ALI) is associated with increased vascular permeability, leukocyte recruitment, and pro-inflammatory mediator release. We investigated the role of the metalloproteinase ADAM17 in endotoxin-induced ALI with focus on endothelial ADAM
Autor:
Anne Koelsch, Andreas Ludwig, Jessica Pruessmeyer, Christian Weber, Matthias Voss, Nicole Schwarz, Franz M. Hess, Alisina Sarabi, Reinhard Windoffer, Elena Pantaler, Antonio Sechi, Daniela Dreymueller, Stefan Uhlig
Publikováno v:
Cellular and Molecular Life Sciences. 67:4233-4248
The surface-expressed transmembrane CX3C chemokine ligand 1 (CX3CL1/fractalkine) induces firm adhesion of leukocytes expressing its receptor CX3CR1. After shedding by the disintegrins and metalloproteinases (ADAM) 10 and 17, CX3CL1 also acts as solub
Autor:
Andreas Ludwig, Jessica Pruessmeyer
Publikováno v:
Seminars in Cell & Developmental Biology. 20:164-174
Various surface molecules undergo regulated cleavage by the disintegrin and metalloproteinases ADAM10 and ADAM17. The list of substrates includes molecules involved in brain pathology, inflammation and cancer. In the brain both proteases mediate neur