Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jessica, Ihne"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 3 (2009)
Subchronic treatment with the psychotomimetic phencyclidine (PCP) has been proposed as a rodent model of the negative and cognitive/executive symptoms of schizophrenia. There has, however, been a paucity of studies on this model in mice, despite the
Externí odkaz:
https://doaj.org/article/aca976c5b74741c0b1d97ee6ff283c77
Autor:
Cara L. Wellman, Mouna Maroun, Paul J. Fitzgerald, Emily M. Drabant, Andrew Holmes, Ahmad R. Hariri, Marguerite Camp, V. Morgan Jones, Jessica Ihne, Ryan Bogdan, Kathryn P. MacPherson
Publikováno v:
Experimental Neurology. 250:260-269
Serotonin is critical for shaping the development of neural circuits regulating emotion. Pet-1 (FEV-1) is an ETS-domain transcription factor essential for differentiation and forebrain targeting of serotonin neurons. Constitutive Pet-1 knockout (KO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e9a2cd5e5e2951d77629855bd8eaa3
https://doi.org/10.1016/j.expneurol.2013.09.025
https://doi.org/10.1016/j.expneurol.2013.09.025
Autor:
Yi-Chyan Chen, Jessica Ihne, Seth G. N. Grant, Rose-Marie Karlsson, Marguerite Camp, Marcelo P. Coba, Bianca Noronha, Andrew Holmes, Michael Feyder, Benita Hurd, Benjamin Palachick
Publikováno v:
Addiction Biology. 16:428-439
The synaptic signaling mechanisms mediating the behavioral effects of ethanol (EtOH) remain poorly understood. Post-synaptic density 95 (PSD-95, SAP-90, Dlg4) is a key orchestrator of N-methyl-D-aspartate receptors (NMDAR) and glutamatergic synapses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e3d74bd17c3ec14836add5c05cf797b
https://doi.org/10.1111/j.1369-1600.2010.00282.x
https://doi.org/10.1111/j.1369-1600.2010.00282.x
Autor:
Rachel A, Daut, Erica F, Busch, Jessica, Ihne, Daniel, Fisher, Masayoshi, Mishina, Seth G N, Grant, Marguerite, Camp, Andrew, Holmes
Publikováno v:
Addiction biology. 20(2)
The neural and genetic factors underlying chronic tolerance to alcohol are currently unclear. The GluN2A N-methyl-D-aspartate receptors (NMDAR) subunit and the NMDAR-anchoring protein PSD-95 mediate acute alcohol intoxication and represent putative m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcf35944ee2a1a44c3859ece4bd4d782
https://pubmed.ncbi.nlm.nih.gov/24397780
https://pubmed.ncbi.nlm.nih.gov/24397780
Autor:
Stefano Gaburro, John F. Cryan, Richard M. O'Connor, Andreas Lüthi, Stephane Ciocchi, Javier A. Bravo, Nicolas Singewald, Lauren DeBrouse, Jessica Ihne, Cara L. Wellman, Kathryn P. MacPherson, Andrew Holmes, Marguerite Camp, Carolyn Graybeal, Lauren Lederle
Mood and anxiety disorders develop in some but not all individuals following exposure to stress and psychological trauma. However, the factors underlying individual differences in risk and resilience for these disorders, including genetic variation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f71683a6271575eab17561b05aaec1
https://europepmc.org/articles/PMC3327858/
https://europepmc.org/articles/PMC3327858/
Psychological stress is a major risk factor for mood and anxiety disorders. However, the phenotypic manifestation of stress effects varies across individuals, likely due, in part, to genetic variation. Modeling the behavioral and neural consequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53946d4c09fe0df4df9b8369ef238a01
https://europepmc.org/articles/PMC3195838/
https://europepmc.org/articles/PMC3195838/
Autor:
Marguerite C, Camp, Michael, Feyder, Jessica, Ihne, Benjamin, Palachick, Benita, Hurd, Rose-Marie, Karlsson, Bianca, Noronha, Yi-Chyan, Chen, Marcelo P, Coba, Seth G N, Grant, Andrew, Holmes
Publikováno v:
Addiction biology. 16(3)
The synaptic signaling mechanisms mediating the behavioral effects of ethanol (EtOH) remain poorly understood. Post-synaptic density 95 (PSD-95, SAP-90, Dlg4) is a key orchestrator of N-methyl-D-aspartate receptors (NMDAR) and glutamatergic synapses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a42a72d12c68625ffc2a48398ad2f113
https://pubmed.ncbi.nlm.nih.gov/21309945
https://pubmed.ncbi.nlm.nih.gov/21309945
Autor:
Roland Bock, Henrik Walter, Andreas Meyer-Lindenberg, Douglas Strathdee, Jessica Ihne, Reza Momenan, Poonam Mathur, Sven Cichon, Andrew Holmes, Seth G. N. Grant, Maria Luisa Scattoni, Jeeva Munasinghe, Carolyn Graybeal, Veronica A. Alvarez, Marcella Rietschel, Peter Kirsch, Michael Feyder, Alison Begg, Marguerite Camp, Matthew Lyman, Rose-Marie Karlsson
Publikováno v:
Feyder, M, Karlsson, R-M, Mathur, P, Lyman, M, Bock, R, Momenan, R, Munasinghe, J, Scattoni, M L, Ihne, J, Camp, M, Graybeal, C, Strathdee, D, Begg, A, Alvarez, V A, Kirsch, P, Rietschel, M, Cichon, S, Walter, H, Meyer-Lindenberg, A, Grant, S G N & Holmes, A 2010, ' Association of Mouse Dlg4 (PSD-95) Gene Deletion and Human DLG4 Gene Variation With Phenotypes Relevant to Autism Spectrum Disorders and Williams' Syndrome ', American Journal of Psychiatry, vol. 167, no. 12, pp. 1508-1517 . https://doi.org/10.1176/appi.ajp.2010.10040484
Objective: Research is increasingly linking autism spectrum disorders and other neurodevelopmental disorders to synaptic abnormalities ("synaptopathies"). PSD-95 (postsynaptic density-95, DLG4) orchestrates protein-protein interactions at excitatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580851e1772d4ca2712e4d34aa5d977d
https://www.pure.ed.ac.uk/ws/files/8711922/Association_of_Mouse_Dlg4.pdf
https://www.pure.ed.ac.uk/ws/files/8711922/Association_of_Mouse_Dlg4.pdf
Autor:
Sachin Patel, Maxine Norcross, Danny G. Winder, Mollee R. Farrell, Jessica Ihne, Marguerite Camp, Masayoshi Mishina, Paul J. Fitzgerald, Elizabeth E. Hill, Cara L. Wellman, Andrew Holmes, Rolf Sprengel, Rose Marie Karlsson, Thomas L. Kash, Khyobeni Mozhui, Kathryn P. Martin, Robert W. Williams, Daniel C. Ciobanu, Carolyn Graybeal
Publikováno v:
The Journal of Neuroscience
Stress is a major risk factor for numerous neuropsychiatric diseases. However, susceptibility to stress and the qualitative nature of stress effects on behavior differ markedly among individuals. This is partly because of the moderating influence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27faba523a05b30ac2282f6aa397fcd1
https://europepmc.org/articles/PMC2866495/
https://europepmc.org/articles/PMC2866495/
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 3 (2009)
Frontiers in Behavioral Neuroscience
Frontiers in Behavioral Neuroscience
Subchronic treatment with the psychotomimetic phencyclidine (PCP) has been proposed as a rodent model of the negative and cognitive/executive symptoms of schizophrenia. There has, however, been a paucity of studies on this model in mice, despite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab7cdad02d9c938a0322745d5746116
http://journal.frontiersin.org/Journal/10.3389/neuro.08.002.2009/full
http://journal.frontiersin.org/Journal/10.3389/neuro.08.002.2009/full