Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jessey, Erath"'
Autor:
Roshan Sivakumar, Katherine Floyd, Jessey Erath, Alex Jacoby, Jenny Kim Kim, Peter O. Bayguinov, James A. J. Fitzpatrick, Dennis Goldfarb, Marko Jovanovic, Abhai Tripathi, Sergej Djuranovic, Slavica Pavlovic-Djuranovic
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Background Plasmodium falciparum, the malaria-causing parasite, is a leading cause of infection-induced deaths worldwide. The preferred treatment approach is artemisinin-based combination therapy, which couples fast-acting artemisinin deriva
Externí odkaz:
https://doaj.org/article/2d249f61461a4b818c93e42e4c485a6e
Autor:
Slavica Pavlovic Djuranovic, Jessey Erath, Ryan J Andrews, Peter O Bayguinov, Joyce J Chung, Douglas L Chalker, James AJ Fitzpatrick, Walter N Moss, Pawel Szczesny, Sergej Djuranovic
Publikováno v:
eLife, Vol 9 (2020)
Plasmodium falciparum is a causative agent of human malaria. Sixty percent of mRNAs from its extremely AT-rich (81%) genome harbor long polyadenosine (polyA) runs within their ORFs, distinguishing the parasite from its hosts and other sequenced organ
Externí odkaz:
https://doaj.org/article/d37acee87930453b87d97c561d9b9e5f
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Malaria is caused by unicellular apicomplexan parasites of the genus Plasmodium, which includes the major human parasite Plasmodium falciparum. The complex cycle of the malaria parasite in both mosquito and human hosts has been studied extensively. T
Externí odkaz:
https://doaj.org/article/2524925d289742148801adfb15a0211b
Autor:
Lori Ferrins, Amrita Sharma, Sarah M Thomas, Naimee Mehta, Jessey Erath, Scott Tanghe, Susan E Leed, Ana Rodriguez, Kojo Mensa-Wilmot, Richard J Sciotti, Kirsten Gillingwater, Michael P Pollastri
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 11, p e0006834 (2018)
We recently reported the medicinal chemistry re-optimization of a series of compounds derived from the human tyrosine kinase inhibitor, lapatinib, for activity against Plasmodium falciparum. From this same library of compounds, we now report potent c
Externí odkaz:
https://doaj.org/article/7cdba245bb1545f0a3fa0706ebb2f1b2
Autor:
Sergej Djuranovic, Jessey Erath
The receptor for activated C-kinase 1 (RACK1), a highly conserved eukaryotic protein, is known to have many, varying biological roles and functions. Previous work has established RACK1 as a ribosomal protein, with defined regions important for bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4729590f2dce9123c7836e9070792b8a
https://doi.org/10.1101/2021.09.21.461325
https://doi.org/10.1101/2021.09.21.461325
Autor:
Julia Medeiros Souza, Everton M Silva, Jessey Erath, Diane Thomas, James H. McKerrow, Lori Ferrins, Baljinder Singh, Erica Penn, Robert F. Campbell, Jair L. Siqueira-Neto, Ana Rodriguez, Jean A. Bernatchez, Susan E. Leed, Norma Roncal, Hitesh B. Jalani, Jasmin Ackermann, Michael P. Pollastri, Dana M. Klug, Laura-Isobel McCall, Kelly A. Bachovchin, Claudia M. Calvet, Richard J. Sciotti, Seema Bag, Melissa J. Buskes
Publikováno v:
ACS Med Chem Lett
[Image: see text] Utilizing a target repurposing and parasite-hopping approach, we tested a previously reported library of compounds that were active against Trypanosoma brucei, plus 31 new compounds, against a variety of protozoan parasites includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9aed31503ad64e9e28813b5711662c
https://doi.org/10.1021/acsmedchemlett.9b00453
https://doi.org/10.1021/acsmedchemlett.9b00453
Autor:
Sergej Djuranovic, Jessey Erath
Publikováno v:
Journal of Biological Chemistry. 298:101954
The receptor for activated C-kinase 1 (RACK1), a highly conserved eukaryotic protein, is known to have many varying biological roles and functions. Previous work has established RACK1 as a ribosomal protein, with defined regions important for ribosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5b655f3531318745af91d9d27136d1
https://doi.org/10.1016/j.jbc.2022.101954
https://doi.org/10.1016/j.jbc.2022.101954
Autor:
Elizabeth Iorns, William Gunn, Jessey Erath, Ana Rodriguez, Jian Zhou, Michael Benzinou, Reproducibility Initiative
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114614 (2014)
This study describes an attempt to replicate experiments from the paper "Effect of BMAP-28 Antimicrobial Peptides on Leishmania major Promastigote and Amastigote Growth: Role of Leishmanolysin in Parasite Survival," which was submitted to the Reprodu
Externí odkaz:
https://doaj.org/article/0979f1124bdd4b54bc3347c7e990e75e
Autor:
Seung Ah Lee, Jessey Erath, Guoan Zheng, Xiaoze Ou, Phil Willems, Daniel Eichinger, Ana Rodriguez, Changhuei Yang
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89712 (2014)
We demonstrate a compact portable imaging system for the detection of waterborne parasites in resource-limited settings. The previously demonstrated sub-pixel sweeping microscopy (SPSM) technique is a lens-less imaging scheme that can achieve high-re
Externí odkaz:
https://doaj.org/article/59c5fde934414727917038da12d3f8f2
Autor:
Walter N. Moss, Jessey Erath, Pawel Szczesny, Slavica Pavlovic Djuranovic, Peter O. Bayguinov, James A. J. Fitzpatrick, Douglas L. Chalker, Ryan J. Andrews, Joyce J Chung, Sergej Djuranovic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5da7827333c8c5e2984bc7bf2f1ada3e
https://doi.org/10.7554/elife.57799.sa2
https://doi.org/10.7554/elife.57799.sa2