Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis

Autor: van Wieringen Wn, Marcel M. Verbeek, Ludwig Kappos, van Swieten Jc, Tove Christensen, Edward J. Wild, Lieke H.H. Meeter, Mattias Vågberg, Ross W. Paterson, Tobias Skillbäck, Lu Ch, Markus Axelsson, Shorena Janelidze, Ulf Andreasson, Maria Bjerke, Jonathan M. Schott, José C. Álvarez-Cermeño, Megan K. Herbert, Nadia K. Magdalinou, Michael Jonsson, Betty M. Tijms, Peter Sundström, Troiano M, Fredrik Piehl, Mohsen Khademi, Pyykkö Ot, Rosanna Tortelli, Jens Kuhle, Lena Brundin, Ales Bartos, Joel Jakobsson, Jessen-Krut J, Michael Khalil, Isabella Laura Simone, Stilund M, Julio C. Rojas, Carole Scherling, Lenka Fialová, David Bäckström, Finn Sellebjerg, Anders Wallin, Jette L. Frederiksen, Pieter Jelle Visser, Signe Modvig, Henrik Zetterberg, Mikael Landén, Mehta, Carla Tortorella, Gudmundur Johannsson, Andrea Malaspina, Giancarlo Logroscino, Pijnenburg Yal, Pérez-Santiago J, Claire Bridel, Weiss A, Romme Christensen J, Niklas Mattsson, Martin Gunnarsson, Alessandro Trentini, Sandberg L, Sara Hall, Kaj Blennow, Lars Forsgren, Ragnarsson O, Oskar Hansson, Jan Lycke, Tomas Olsson, Magnus Gisslén, Joachim Burman, Carsten Wikkelsö, Anders Svenningsson, Luisa M. Villar, Leinonen, Martin R Turner, Charlotte E. Teunissen, Elizabeth Gray, A. Boxer

Publikováno v: JAMA Neurol
JAMA Neurology, 76(9), 1035-1048. American Medical Association
Bridel, C, van Wieringen, W N, Zetterberg, H, Tijms, B M, Teunissen, C E, Alvarez-Cermeño, J C, Andreasson, U, Axelsson, M, Bäckström, D C, Bartos, A, Bjerke, M, Blennow, K, Boxer, A, Brundin, L, Burman, J, Christensen, T, Fialová, L, Forsgren, L, Frederiksen, J L, Gisslén, M, Gray, E, Gunnarsson, M, Hall, S, Hansson, O, Herbert, M K, Jakobsson, J, Jessen-Krut, J, Janelidze, S, Johannsson, G, Jonsson, M, Kappos, L, Khademi, M, Khalil, M, Kuhle, J, Landén, M, Leinonen, V, Logroscino, G, Lu, C-H, Lycke, J, Magdalinou, N K, Malaspina, A, Mattsson, N, Meeter, L H, Mehta, S R, Modvig, S, Olsson, T, Paterson, R W, Pérez-Santiago, J, Piehl, F, Pijnenburg, Y A L, Pyykkö, O T, Ragnarsson, O, Rojas, J C, Romme Christensen, J, Sandberg, L, Scherling, C S, Schott, J M, Sellebjerg, F T, Simone, I L, Skillbäck, T, Stilund, M, Sundström, P, Svenningsson, A, Tortelli, R, Tortorella, C, Trentini, A, Troiano, M, Turner, M R, van Swieten, J C, Vågberg, M, Verbeek, M M, Villar, L M, Visser, P J, Wallin, A, Weiss, A, Wikkelsø, C & Wild, E J 2019, ' Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis ', JAMA Neurology, vol. 76, no. 9, pp. 1035-1048 . https://doi.org/10.1001/jamaneurol.2019.1534
Jama Neurology, 76, 9, pp. 1035-1048
Bridel, C, van Wieringen, W N, Zetterberg, H, Tijms, B M, Teunissen, C E & the NFL Group 2019, ' Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology : A Systematic Review and Meta-analysis ', J A M A Neurology, vol. 76, no. 9, pp. 1035-1048 . https://doi.org/10.1001/jamaneurol.2019.1534
Jama Neurology, 76, 1035-1048

Key PointsQuestionHow do levels of neurofilament light in cerebrospinal fluid (cNfL) compare between neurological conditions and with healthy controls? FindingsAmong 10 059 individuals in this systematic review and meta-analysis, cNfL was elevated in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca7710d56e5da4c14e9fc00b7f90be0
https://pubmed.ncbi.nlm.nih.gov/31206160

Biomarker evidence of axonal injury in neuroasymptomatic HIV-1 patients.

Autor: Jessen Krut J; Institute of Biomedicine, Department of Infectious Diseases, University of Gothenburg, Gothenburg, Sweden., Mellberg T; Institute of Biomedicine, Department of Infectious Diseases, University of Gothenburg, Gothenburg, Sweden., Price RW; Department of Neurology, University of California San Francisco, San Francisco, California, United States of America., Hagberg L; Institute of Biomedicine, Department of Infectious Diseases, University of Gothenburg, Gothenburg, Sweden., Fuchs D; Division of Biological Chemistry, Biocenter, Innsbruck Medical University, Innsbruck, Austria., Rosengren L; Institute of Neuroscience and Physiology, Department of Neurology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Nilsson S; Mathematical Sciences, Chalmers University of Technology, Gothenburg, Sweden., Zetterberg H; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden ; UCL Institute of Neurology, Queen Square, London, United Kingdom., Gisslén M; Institute of Biomedicine, Department of Infectious Diseases, University of Gothenburg, Gothenburg, Sweden.

Publikováno v: PloS one [PLoS One] 2014 Feb 11; Vol. 9 (2), pp. e88591. Date of Electronic Publication: 2014 Feb 11 (Print Publication: 2014).