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eIF4E-Targeted Suicide Gene Therapy in a Minimal Residual Mouse Model for Metastatic Soft-Tissue Head and Neck Squamous Cell Carcinoma Improves Disease-Free Survival

Autor: Jesse Tubbs, Arrigo DeBenedetti, Carol Meschonat, Ghali E. Ghali, Benjamin D.L. Li, Neal T. Holm, Christopher Cefalu, Guang Sun, J. Michael Mathis, Yoshinobu Odaka, Quyen D. Chu, Bradford Siegele

Publikováno v: Journal of Surgical Research. 148:83-89

Background Translation initiation factor eIF4E unwinds long 5′-untranslated regions of certain tightly regulated mRNAs and, thereby, facilitates their translation into proteins. eIF4E has been shown to be overexpressed in a majority of solid tumors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84e9a5e19a651c54ac9cd794589e760
https://doi.org/10.1016/j.jss.2008.03.011

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Evaluation of the setup accuracy of a stereotactic radiotherapy head immobilization mask system using kV on-board imaging

Autor: Spencer Thompson, Jesse Tubbs, Imad Ali, Ozer Algan, Kerry Hibbitts, Terence S. Herman, Salahuddin Ahmad

Publikováno v: Journal of Applied Clinical Medical Physics

The purpose of this study was to evaluate setup accuracy and quantify random and systematic errors of the BrainLAB stereotactic immobilization mask and localization system using kV on‐board imaging. Nine patients were simulated and set up with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f294c866736e6013514c7ae893ee1c5
https://pubmed.ncbi.nlm.nih.gov/20717086

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Erratum to: Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer

Autor: Jesse Tubbs, J. Michael Mathis, Mary Lowery-Nordberg, Marcia Unger, John L. Clifford, Heather E. Kleiner, Patrick Adegboyega, Runhua Shi, Arrigo De Benedetti, Benjamin Dl Li, James A. Cardelli, Carol Meschonat, Mark Smith, Prasad Krishnan, Quyen D. Chu

Publikováno v: Journal of Experimental & Clinical Cancer Research. 28

Correction to Kleiner HE, Krishnan P, Tubbs J, Smith M, Meschonat C, Shi R, Lowery-Nordberg M, Adegboyega P, Unger M, Cardelli J et al: Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer. J Exp Clin Cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a5f5cf8889189b70c960e9fca0ff91e
https://doi.org/10.1186/1756-9966-28-54

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Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer

Autor: Marcia Unger, Prasad Krishnan, Heather E. Kleiner, John L. Clifford, Jesse Tubbs, Runhua Shi, Quyen D. Chu, J. Michael Mathis, Carol Meschonat, Mary Lowery-Nordberg, Patrick Adegboyega, James A. Cardelli, Arrigo De Benedetti, Mark Smith, Benjamin D.L. Li

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 28, Iss 1, p 54 (2009)
Journal of Experimental & Clinical Cancer Research, Vol 28, Iss 1, p 5 (2009)
Journal of Experimental & Clinical Cancer Research : CR

Background Eukaryotic initiation factor 4E (eIF4E) is elevated in many cancers and is a prognostic indicator in breast cancer. Many pro-tumorigenic proteins are selectively translated via eIF4E, including c-Myc, cyclin D1, ornithine decarboxylase (OD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81942a66b4786319574f4d1312271fec
http://www.jeccr.com/content/28/1/54

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Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats

Autor: Jesse Tubbs, Benjamin D.L. Li, Heather E Kleiner-Hancock, C. Marcelo Aldaz, Jerry McLarty, David Windler, Prasad Krishnan, Robert Grand, Karen J. Yan

Publikováno v: BMC Cancer
BMC Cancer, Vol 9, Iss 1, p 259 (2009)

Background Breast cancer is a major problem in the United States leading to tens of thousands of deaths each year. Although citrus auraptene suppresses cancer in numerous rodent models, its role in breast cancer prevention previously has not been rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de73c39152de69073b37825ff719060c
http://europepmc.org/articles/PMC2724550

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SU-FF-T-550: Evaluation of Setup Accuracy of a Stereotactic Radiotherapy Head Immobilization Mask Using KV On-Board Imaging

Autor: Teresa Langley, Kerry Hibbitts, Terence S. Herman, Spencer Thompson, Imad Ali, Ozer Algan, Salahuddin Ahmad, Jesse Tubbs

Publikováno v: Medical Physics. 36:2651-2651

Purpose: To evaluate setup accuracy of the BrainLAB stereotactic radiotherapy head immobilization mask using orthogonal projections from on‐board imaging.Materials and Methods: Eight patients were simulated and treated with the BrainLAB stereotacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34a5277f594243a13c8fb504d1f6952a
https://doi.org/10.1118/1.3182048

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156. Translation Initiation Factor eIF4E-Targeted Suicide Gene Therapy Following Cytoreductive Surgery Improves Disease Free Survival in a Mouse Soft Tissue Metastasis Model for Head and Neck Squamous Cell Carcinoma

Autor: Guang Sun, J. Michael Mathis, Bradford J. Siegele, Benjamin D.L. Li, Neal Holm, Carol Meschonat, Jesse Tubbs, Ghali E. Ghali, Quyen D. Chu, Christopher Cefalu, Yoshinobu Odaka

Publikováno v: Journal of Surgical Research. 144:246

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb3622cc8a08e324fb1c559ce523ba50
https://doi.org/10.1016/j.jss.2007.12.177

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