Výsledky vyhledávání - "Jesse Schloegel"

Identification of an Immunogenic Broadly Inhibitory Surface Epitope of the Plasmodium vivax Duffy Binding Protein Ligand Domain

Autor: Samantha J. Barnes, John H. Adams, Miriam T. George, Jesse Schloegel, Joanne L. Casey, Francis B. Ntumngia, Christopher L. King, Michael Foley

Publikováno v: mSphere
mSphere, Vol 4, Iss 3 (2019)
mSphere, Vol 4, Iss 3, p e00194-19 (2019)

Vivax malaria is the second leading cause of malaria worldwide and the major cause of non-African malaria. Unfortunately, efforts to develop antimalarial vaccines specifically targeting Plasmodium vivax have been largely neglected, and few candidates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e909d4246c1234588a9b364a02997cf1
http://europepmc.org/articles/PMC6520440

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Fine Specificity of Plasmodium vivax Duffy Binding Protein Binding Engagement of the Duffy Antigen on Human Erythrocytes

Autor: Asim A. Siddiqui, Francis B. Ntumngia, Michael Foley, Joanne L. Casey, Jia Xainli, Jesse Schloegel, Lenore L. Carias, Menachem Shoham, John H. Adams, Christopher L. King

Publikováno v: Infection and Immunity. 80:2920-2928

Plasmodium vivax invasion of human erythrocytes requires interaction of the P. vivax Duffy binding protein (PvDBP) with its host receptor, the Duffy antigen (Fy) on the erythrocyte surface. Consequently, PvDBP is a leading vaccine candidate. The bind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f57fff37fc15b6f48d8f8e0380697dc
https://doi.org/10.1128/iai.00206-12

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Immunogenicity of a Synthetic Vaccine Based on Plasmodium vivax Duffy Binding Protein Region II

Autor: Jesse Schloegel, Samantha J. Barnes, Miriam T. George, Francis B. Ntumngia, Amy M. McHenry, John H. Adams

Molecules that play a role inPlasmodiummerozoite invasion of host red blood cells represent attractive targets for blood-stage vaccine development against malaria. InPlasmodium vivax, merozoite invasion of reticulocytes is mediated by the Duffy bindi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2367d661846a22b8eae3433dc9c6f649
https://europepmc.org/articles/PMC4178564/

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Immunogenicity of Single versus Mixed Allele Vaccines of Plasmodium vivax Duffy Binding Protein Region II

Autor: Samantha J. Barnes, Francis B. Ntumngia, John H. Adams, Jesse Schloegel, Miriam T. George, Amy M. McHenry, Sandra Kennedy

The Duffy binding protein (DBP) of Plasmodium vivax is vital for host erythrocyte invasion. DBP region II (DBPII) contains critical residues for receptor recognition and anti-DBPII antibodies have been shown to inhibit erythrocyte binding and invasio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7f5d738c8f560eb4604eb537c515f2
https://europepmc.org/articles/PMC4497540/

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Conserved and variant epitopes of Plasmodium vivax Duffy binding protein as targets of inhibitory monoclonal antibodies

Autor: Christopher L. King, Samantha J. Barnes, Jesse Schloegel, Francis B. Ntumngia, Amy M. McHenry, Sanjay Singh, John H. Adams

Publikováno v: Infection and immunity. 80(3)

The Duffy binding protein (DBP) is a vital ligand for Plasmodium vivax blood-stage merozoite invasion, making the molecule an attractive vaccine candidate against vivax malaria. Similar to other blood-stage vaccine candidates, DBP allelic variation e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce23a4cfd138166ae90bdb9a87933cf6
https://pubmed.ncbi.nlm.nih.gov/22215740

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Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils

Autor: Vince J. Murphy, Vivian Kienzle, Kleo Vingas, Rosella. Masciantonio, Lynne J. Waddington, Michael Foley, Gert H. Talbo, Jesse Schloegel, Geoffrey J. Howlett, Anthony N. Hodder, Margaret Sunde, Robin F. Anders, Christopher G. Adda

Publikováno v: Molecular and biochemical parasitology. 166(2)

Several merozoite surface proteins are being assessed as potential components of a vaccine against Plasmodium falciparum, the cause of the most serious form of human malaria. One of these proteins, merozoite surface protein 2 (MSP2), is unusually hyd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670b212503c79aadabaca43714767dca
https://pubmed.ncbi.nlm.nih.gov/19450733

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Retraction for Siddiqui et al., Fine Specificity of Plasmodium vivax Duffy Binding Protein Binding Engagement of the Duffy Antigen on Human Erythrocytes

Autor: Jia Xainli, Asim A. Siddiqui, Lenore L. Carias, Michael Foley, Francis B. Ntumngia, Jesse Schloegel, Christopher L. King, Joanne L. Casey, John H. Adams, Menachem Shoham

Publikováno v: Infection and Immunity. 83:2593-2593

Volume 80, no. 8, p. [2920–2928][1], 2012. The authors hereby retract this article. The authors have been alerted that the published manuscript contains several images that do not accurately reflect the experimental data. Specifically, some of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb71c69931d163c1fa92d8b59f6f2f99
https://doi.org/10.1128/iai.00338-15

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Plasmodium vivax Duffy binding protein: understanding targets of protective immunity

Autor: Samantha J. Barnes, Francis B. Ntumngia, Miriam T. George, Jesse Schloegel, John H. Adams, Amy M. McHenry

Publikováno v: Malaria Journal

Plasmodium vivax merozoite invasion of reticulocytes is a rapid process that involves a series of specific, sequential interactions. These interactions are crucial for invasion and continued blood-stage infection, thus representing attractive targets

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac04540ade7a22a012550629773a43a9

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