Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jesse S. Kerr"'
Autor:
Nigel H. Greig, Mansour Akbari, P Rocktäschel, M Z Cader, Konstantinos Palikaras, Domenica Caponio, Sofie Lautrup, Beimeng Yang, Xiuli Dan, Yujun Hou, Mark P. Mattson, Nektarios Tavernarakis, Deborah L. Croteau, Evandro Fei Fang, Mahdi Hasan-Olive, Hilde Nilsen, Tormod Fladby, Jesse S. Kerr, Vilhelm A. Bohr, Bryan A. Adriaanse
Publikováno v:
Nature Neuroscience
Autophagy
Autophagy
Our latest publication on the inhibition of Alzheimer disease (AD) through mitophagy consolidates the ‘defective mitophagy hypothesis of AD etiology’. Dementia (majorly AD) affects over 50 million people worldwide, and for AD there is no cure. AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709f90758c19c03196f13e7d1bb256d8
Autor:
Huiming Lu, Jane Tian, Jesse S. Kerr, David A. Sinclair, Tyler B. Waltz, Mark P. Mattson, Ravi Chand Bollineni, Sumana Kalyanasundaram, Morten Scheibye-Knudsen, Hilde Nilsen, Henok Kassahun, Marya Morevati, Qiping Lu, Wendy B. Iser, Raghavendra A. Shamanna, Jun Li, Mark A. Wilson, Deborah L. Croteau, Vilhelm A. Bohr, Evandro Fei Fang, Bradley N. Wollman, Krisztina Marosi
Publikováno v:
Cell Metabolism. 24:566-581
Ataxia telangiectasia (A-T) is a rare autosomal recessive disease characterized by progressive neurodegeneration and cerebellar ataxia. A-T is causally linked to defects in ATM, a master regulator of the response to and repair of DNA double-strand br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ff2ea080c179fda0d7e67f2b55e113
https://doi.org/10.1016/j.cmet.2016.09.004
https://doi.org/10.1016/j.cmet.2016.09.004
Autor:
Jesse S. Kerr, Hilde Nilsen, Nektarios Tavernarakis, Joanna Poulton, Konstantinos Palikaras, Nuo Sun, Eszter Dombi, Evandro Fei Fang, Vilhelm A. Bohr, Elayne M. Fivenson, Yujun Hou, Ryan Spangler, Stephanie Cordonnier, Henok Kassahun
Publikováno v:
Journal of Visualized Experiments.
Mitochondria are the powerhouses of cells and produce cellular energy in the form of ATP. Mitochondrial dysfunction contributes to biological aging and a wide variety of disorders including metabolic diseases, premature aging syndromes, and neurodege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d29c79fb6c04a1445d2610b4a45643
https://doi.org/10.3791/56301
https://doi.org/10.3791/56301
Autor:
Ilya G. Goldberg, Elin Lehrmann, Henok Kassahun, Tyler B. Waltz, Kevin G. Becker, Krisztina Marosi, Bradley N. Wollman, Mark P. Mattson, Evandro Fei Fang, Qiping Lu, Jesse S. Kerr, Elayne M. Fivenson, Yongqing Zhang, Mark A. Wilson, Morten Scheibye-Knudsen, Hilde Nilsen, Wendy B. Iser, Vilhelm A. Bohr, D. Mark Eckley, Marya Morevati
Publikováno v:
Scientific Reports
Fang, E F, Waltz, T B, Kassahun, H, Lu, Q, Kerr, J S, Morevati, M, Fivenson, E M, Wollman, B N, Marosi, K, Wilson, M A, Iser, W B, Eckley, D M, Zhang, Y, Lehrmann, E, Goldberg, I G, Scheibye-Knudsen, M, Mattson, M P, Nilsen, H, Bohr, V A & Becker, K G 2017, ' Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway ', Scientific Reports, vol. 7, 46208 . https://doi.org/10.1038/srep46208
Fang, E F, Waltz, T B, Kassahun, H, Lu, Q, Kerr, J S, Morevati, M, Fivenson, E M, Wollman, B N, Marosi, K, Wilson, M A, Iser, W B, Eckley, D M, Zhang, Y, Lehrmann, E, Goldberg, I G, Scheibye-Knudsen, M, Mattson, M P, Nilsen, H, Bohr, V A & Becker, K G 2017, ' Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway ', Scientific Reports, vol. 7, 46208 . https://doi.org/10.1038/srep46208
Aging is a major international concern that brings formidable socioeconomic and healthcare challenges. Small molecules capable of improving the health of older individuals are being explored. Small molecules that enhance cellular stress resistance ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b040e8b2db4a8ee6f3871bbb80c8674
http://europepmc.org/articles/PMC5387417
http://europepmc.org/articles/PMC5387417
Autor:
Nigel H. Greig, Evandro Fei Fang, M. Zameel Cader, Jesse S. Kerr, Mark P. Mattson, Bryan A. Adriaanse, Vilhelm A. Bohr
Neurons affected in Alzheimer's disease (AD) experience mitochondrial dysfunction and a bioenergetic deficit that occurs early and promotes the disease-defining amyloid beta peptide (Aβ) and Tau pathologies. Emerging findings suggest that the autoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da5a58962d30c0da1dd7821541b0617
https://europepmc.org/articles/PMC5341618/
https://europepmc.org/articles/PMC5341618/
Autor:
Evandro Fei, Fang, Henok, Kassahun, Deborah L, Croteau, Morten, Scheibye-Knudsen, Krisztina, Marosi, Huiming, Lu, Raghavendra A, Shamanna, Sumana, Kalyanasundaram, Ravi Chand, Bollineni, Mark A, Wilson, Wendy B, Iser, Bradley N, Wollman, Marya, Morevati, Jun, Li, Jesse S, Kerr, Qiping, Lu, Tyler B, Waltz, Jane, Tian, David A, Sinclair, Mark P, Mattson, Hilde, Nilsen, Vilhelm A, Bohr
Publikováno v:
Cell metabolism. 24(4)
Ataxia telangiectasia (A-T) is a rare autosomal recessive disease characterized by progressive neurodegeneration and cerebellar ataxia. A-T is causally linked to defects in ATM, a master regulator of the response to and repair of DNA double-strand br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50652ffe2015c5864bd8f9abdb9dfbaa
https://pubmed.ncbi.nlm.nih.gov/27732834
https://pubmed.ncbi.nlm.nih.gov/27732834