Zobrazeno 1 - 10
of 1 299
pro vyhledávání: '"Jesse Roman"'
Autor:
Ross Summer, Jamie L. Todd, Megan L. Neely, L. Jason Lobo, Andrew Namen, L. Kristin Newby, Shirin Shafazand, Sally Suliman, Christian Hesslinger, Sascha Keller, Thomas B. Leonard, Scott M. Palmer, Olga Ilkayeva, Michael J. Muehlbauer, Christopher B. Newgard, Jesse Roman
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background The circulating metabolome, reflecting underlying cellular processes and disease biology, has not been fully characterized in patients with idiopathic pulmonary fibrosis (IPF). We evaluated whether circulating levels of metabolite
Externí odkaz:
https://doaj.org/article/15b5c1581a9148c1af3a23b566f2b730
Autor:
Jesse Roman
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 945 (2023)
Wound healing is triggered by inflammation elicited after tissue injury. Mesenchymal cells, specifically fibroblasts, accumulate in the injured tissues, where they engage in tissue repair through the expression and assembly of extracellular matrices
Externí odkaz:
https://doaj.org/article/6e5b7dbf361f4862ae49df44c808dbc4
Autor:
Jamie L. Todd, Megan L. Neely, Robert Overton, Katey Durham, Mridu Gulati, Howard Huang, Jesse Roman, L. Kristin Newby, Kevin R. Flaherty, Richard Vinisko, Yi Liu, Janine Roy, Ramona Schmid, Benjamin Strobel, Christian Hesslinger, Thomas B. Leonard, Imre Noth, John A. Belperio, Scott M. Palmer, on behalf of the IPF-PRO Registry investigators
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease for which diagnosis and management remain challenging. Defining the circulating proteome in IPF may identify targets for biomarker development. We sought to quantif
Externí odkaz:
https://doaj.org/article/e7e9aa1e37874cbe8ab7871c8f6fedf1
Autor:
Ross Summer, Rachana Krishna, DeLeila Schriner, Karina Cuevas-Mora, Dominic Sales, Rachel Para, Jesse Roman, Carl Nieweld, Bernadette R. Gochuico, Freddy Romero
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-11 (2019)
Abstract Background Hermansky-Pudlak syndrome (HPS) is a rare autosomal recessive disorder characterized by oculocutaneous albinism and platelet dysfunction and can sometimes lead to a highly aggressive form of pulmonary fibrosis that mimics the fata
Externí odkaz:
https://doaj.org/article/36447cb2717748b1901a10a4163240d2
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Work-place exposure to silica dust may lead to progressive lung inflammation culminating in the development of silicosis, an irreversible condition that can be complicated by onset of pulmonary hypertension (PH). The molecular mec
Externí odkaz:
https://doaj.org/article/271cdd2812c9428e98f0e561a58e7619
Autor:
Glenn W. Vicary, Jeffrey D. Ritzenthaler, Tanmay S. Panchabhai, Edilson Torres-González, Jesse Roman
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Tobacco-related chronic lung diseases are characterized by alterations in lung architecture leading to decreased lung function. Knowledge of the exact mechanisms involved in tobacco-induced tissue remodeling and inflammation remai
Externí odkaz:
https://doaj.org/article/36a411bfed48487c8200b57cf0d3ed3b
Publikováno v:
Respiratory Medicine Case Reports, Vol 22, Iss C, Pp 109-112 (2017)
Scleroderma-related interstitial lung disease (SSc-ILD) is a pulmonary fibrosing disorder characterized by systemic inflammation and progressive scarring of the lungs that leads to respiratory failure. Although certain immunosuppressive therapies may
Externí odkaz:
https://doaj.org/article/82e89f58f8524ec4accdf12831d69060
Autor:
Martin Kolb, Benjamin Bondue, Alberto Pesci, Yasunari Miyazaki, Jin Woo Song, Nitin Y. Bhatt, John T. Huggins, Justin M. Oldham, Maria L. Padilla, Jesse Roman, Shane Shapera
Publikováno v:
European Respiratory Review, Vol 27, Iss 150 (2018)
Acute exacerbation of interstitial lung disease (ILD) is associated with a poor prognosis and high mortality. Numerous studies have documented acute exacerbation in idiopathic pulmonary fibrosis (IPF), but less is known about these events in other IL
Externí odkaz:
https://doaj.org/article/8a2c3f914c894555949d5985b00b7cf8
Autor:
Juliane I. Beier, Luping Guo, Swati Joshi-Barve, Jeffrey D. Ritzenthaler, Jesse Roman, Gavin E. Arteel
Publikováno v:
Annals of Hepatology, Vol 15, Iss 5, Pp 762-772 (2016)
Background. The regenerative capacity of the liver is critical for proper responses to injury. Fibrin extracellular matrix (ECM) deposition is a common response to insult and contributes to inflammatory liver injury. However, the role of this matrix
Externí odkaz:
https://doaj.org/article/ec5ba9c02e124c2eb11fb40091d20247
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 305-315 (2016)
Pulmonary fibrosis affects millions worldwide and, even though there has been a significant investment in understanding the processes involved in wound healing and maladaptive repair, a complete understanding of the mechanisms responsible for lung fi
Externí odkaz:
https://doaj.org/article/4b32acb5f59c4ee581afa90244f44bf7