Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jesse R Huang"'
Autor:
Jonathan M Craig, Maria Mills, Hwanhee C Kim, Jesse R Huang, Sarah J Abell, Jonathan W Mount, Jens H Gundlach, Keir C Neuman, Andrew H Laszlo
Publikováno v:
Nucleic Acids Research. 50:10601-10613
Helicases are essential for nearly all nucleic acid processes across the tree of life, yet detailed understanding of how they couple ATP hydrolysis to translocation and unwinding remains incomplete because their small (∼300 picometer), fast (∼1 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680fb19d5356eb163f2d0420fa5a135f
https://doi.org/10.1093/nar/gkac837
https://doi.org/10.1093/nar/gkac837
Autor:
Christopher A. Thomas, Jonathan M. Craig, Shuichi Hoshika, Henry Brinkerhoff, Jesse R. Huang, Sarah J. Abell, Hwanhee C. Kim, Michaela C. Franzi, Jessica D. Carrasco, Hyo-Joong Kim, Drew C. Smith, Jens H. Gundlach, Steven A. Benner, Andrew H. Laszlo
Publikováno v:
Journal of the American Chemical Society.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9faf73fad61ffb8c68e33e8876c2ea05
https://doi.org/10.1021/jacs.3c00829
https://doi.org/10.1021/jacs.3c00829
Autor:
Alan Shaw, Jonathan M. Craig, Hossein Amiri, Jeonghoon Kim, Heather E. Upton, Sydney C. Pimentel, Jesse R. Huang, Susan Marqusee, Jens H. Gundlach, Kathleen Collins, Carlos J. Bustamante
Techniques that can directly sequence RNAs and determine secondary structures are essential to establish how an RNA molecule folds and how folding affects its function. We describe the development of a direct RNA nanopore sequencing technique using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aaa4a7f0575975f04797cedb8dcba36
https://doi.org/10.1101/2023.04.05.535757
https://doi.org/10.1101/2023.04.05.535757
Autor:
Sinduja K. Marx, Keith J. Mickolajczyk, Jonathan M. Craig, Christopher A. Thomas, Akira M. Pfeffer, Sarah J. Abell, Jessica D. Carrasco, Michaela C. Franzi, Jesse R. Huang, Hwanhee C. Kim, Henry D. Brinkerhoff, Tarun M. Kapoor, Jens H. Gundlach, Andrew H. Laszlo
Publikováno v:
bioRxiv : the preprint server for biology.
The genome of SARS-CoV-2 encodes for a helicase called nsp13 that is essential for viral replication and highly conserved across related viruses, making it an attractive antiviral target. Here we use nanopore tweezers, a high-resolution single-molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ac5eeb6c8305d406edbe3e8fe0302f
https://pubmed.ncbi.nlm.nih.gov/36238723
https://pubmed.ncbi.nlm.nih.gov/36238723
Autor:
Andrew H. Laszlo, Jonathan M. Craig, Momčilo Gavrilov, Ramreddy Tippana, Ian C. Nova, Jesse R. Huang, Hwanhee C. Kim, Sarah J. Abell, Mallory deCampos-Stairiker, Jonathan W. Mount, Jasmine L. Bowman, Katherine S. Baker, Hugh Higinbotham, Dmitriy Bobrovnikov, Taekjip Ha, Jens H. Gundlach
We used single-molecule picometer-resolution nanopore tweezers (SPRNT) to resolve the millisecond single-nucleotide steps of superfamily 1 helicase PcrA as it translocates on, or unwinds, several kilobase-long DNA molecules. We recorded more than two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d0b1870c4e8e88f72ee1da32ff0d82
https://doi.org/10.1101/2022.02.10.479955
https://doi.org/10.1101/2022.02.10.479955
Publikováno v:
Biophysical Journal. 122:108a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ded27ba6b70d58b0fa75d1271e221704
https://doi.org/10.1016/j.bpj.2022.11.766
https://doi.org/10.1016/j.bpj.2022.11.766
Autor:
Jesse R. Huang, Hwanhee C. Kim, Maria Mills, Jonathan M. Craig, Jonathan W. Mount, Andrew H. Laszlo, Keir C. Neuman, Sarah J. Abell, Jens H. Gundlach
Helicases are essential for nearly all nucleic acid processes across the tree of life. Using Nanopore Tweezers we observed the small, fast steps taken by single RecQ helicases as they step along and unwind DNA at ultrahigh spatiotemporal resolution.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbd06c5933fd87348a0e8b3b21ba2132
https://doi.org/10.1101/2021.09.23.461529
https://doi.org/10.1101/2021.09.23.461529
Autor:
Christopher A. Thomas, Jonathan M. Craig, Shuichi Hoshika, Andrew H. Laszlo, Jesse R. Huang, Sarah J. Abell, Hwanhee C. Kim, Jessica Carrasco, Michaela C. Franzi, Steven A. Benner, Jens H. Gundlach
Publikováno v:
Biophysical Journal. 121:209a-210a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::897ca83c96c03c4b7799539dac5585f8
https://doi.org/10.1016/j.bpj.2021.11.1671
https://doi.org/10.1016/j.bpj.2021.11.1671
Autor:
Jens H. Gundlach, Matthew T. Noakes, Hwanhee C. Kim, Brooke A. Anderson, Jonathan M. Craig, Ramanarayanan Krishnamurthy, Jesse R. Huang, Rebekah J Karadeema, Michael P. Ledbetter, Sarah J. Abell, Floyd E. Romesberg
Publikováno v:
J Am Chem Soc
Unnatural base pairs (UBPs) have been developed and used for a variety of in vitro applications, as well as for the engineering of semi-synthetic organisms (SSOs) that store and retrieve increased information. However, these applications are limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0198d0b4025d8e82ca351a2a0986a6d4
https://europepmc.org/articles/PMC7263177/
https://europepmc.org/articles/PMC7263177/
Autor:
Jesse R. Huang, Cameron M. Chow, David Baker, Anastassia A. Vorobieva, Stacey Gerben, Hwanhee C. Kim, Jonathan M. Craig, Sinduja Marx, Sarah J. Abell, Jens H. Gundlach
Publikováno v:
Biophysical Journal. 118:483a-484a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309162566a91177110bebf9539e41e64
https://doi.org/10.1016/j.bpj.2019.11.2678
https://doi.org/10.1016/j.bpj.2019.11.2678