Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Jesse M. Jaynes"'
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective Toxoplasma gondii, an intracellular zoonotic parasite, infects approximately a third of the world population. Current drugs for treatment of T. gondii infection have been challenged with ineffectiveness and adverse side effects. Th
Externí odkaz:
https://doaj.org/article/3ef4d50afa484ce2b4fdc95d727f160d
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The relentless growth of multidrug resistance and generation of recalcitrant biofilm are major obstacles in treating wounds, particularly in austere military environments where broad-spectrum pathogen coverage is needed. Designed antimicrobial peptid
Externí odkaz:
https://doaj.org/article/12cc5f86d5064d8e99488018b6a67ad3
Publikováno v:
Journal of Fungi, Vol 6, Iss 3, p 184 (2020)
Cutaneous invasive fungal wound infections after life-threatening dismounted complex blast injury (DCBI) and natural disasters complicate clinical care. These wounds often require aggressive repeated surgical debridement, can result in amputations an
Externí odkaz:
https://doaj.org/article/e27a9be06ada4a478ad52c90b0ec5247
Publikováno v:
Plant Disease.
Optimizing synthetic antimicrobial peptides for safe and enhanced activity against fungal and bacterial pathogens is useful for genetic engineering of plants for resistance to plant pathogens and their associated mycotoxins. Nine synthetic peptides m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b2e29f597b77092ca9b2c4c563c335a
https://doi.org/10.1094/pdis-11-22-2572-re
https://doi.org/10.1094/pdis-11-22-2572-re
Autor:
Jesse M. Jaynes, George R. Martin, Chris Andrews, Anghesom Ghebremedhin, Hui-Xian Lin, Benjamin Adu-Addai, Steve Noonan, Ahmad Bin Salam, Shakir Uddin Ahmed, Richard Stratton, Henry Lopez, Udo Rudloff, Balasubramanyam Karanam, Chandra Khantwal, Clayton Yates
Publikováno v:
bioRxiv
Activated M2 polarized macrophages are drivers of pulmonary fibrosis in several clinical scenarios such as Acute Respiratory Disease Syndrome (ARDS) and Idiopathic Pulmonary Fibrosis (IPF), through the production of inflammatory and fibrosis-inducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63abba64d7670ebb3fbb40ccf165a761
https://doi.org/10.1101/2020.07.27.218115
https://doi.org/10.1101/2020.07.27.218115
Autor:
Raul Calvo, Noel Southall, Lixin Fan, Chan Young Ock, Keyur Talsania, Clayton Yates, Taylor Aiken, Yansong Bian, Zachary Knotts, Yongmei Zhao, Jesse M. Jaynes, Jason White, Abisola Abisoye-Ogunniyan, Taivan Odzorig, Anghesom Ghebremedhin, Myagmarjav Dashnyam, Anton Simeonov, Sarangan Ravichandran, Nathan Pate, Amber E. de Groot, Michael Ronzetti, Xin Hu, Vicky Chen, Jelani C. Zarif, Henry Lopez, Bolormaa Baljinnyam, Parimal Kumar, Dandan Li, Natalia de Val, Theresa Guerin, Wendy Bautista, Ahmad Bin Salam, Rushikesh Sable, Juan J. Marugan, Marc Ferrer, Serguei Kozlov, Victoria Nguyen, Monika Mehta, Balasubramanyam Karanam, Ruksana Amin, Mones Abu-Asab, Udo Rudloff, Anju Singh
Publikováno v:
Sci Transl Med
Solid tumors elicit a detectable immune response including the infiltration of tumor-associated macrophages (TAMs). Unfortunately, this immune response is co-opted into contributing toward tumor growth instead of preventing its progression. We seek t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513d18826af0875f5379d90cda6894d2
https://doi.org/10.1126/scitranslmed.aax6337
https://doi.org/10.1126/scitranslmed.aax6337
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
BMC Research Notes
BMC Research Notes
Objective Toxoplasma gondii, an intracellular zoonotic parasite, infects approximately a third of the world population. Current drugs for treatment of T. gondii infection have been challenged with ineffectiveness and adverse side effects. This necess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05874e14444262dccaaeb5d2118693d5
https://doi.org/10.1186/s13104-019-4732-z
https://doi.org/10.1186/s13104-019-4732-z
Autor:
Christopher P. Denton, Bahja Ahmed Abdi, James Stanway, Kimti Kumar, Nikita Arumalla, Sarah Karrar, George M. Martin, Xu Shiwen, Jesse M. Jaynes, David Abraham, Henry Lopez, Richard Stratton, Sian Morris
Publikováno v:
Oral Presentations.
Background In systemic sclerosis, activated macrophages having M2-like properties are believed to contribute to the fibrotic pathology by secreting profibrotic factors such as TGFβ. Certain synthetic peptides (10-12mers) studied here coopt the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3994a54634b7d8de430212337a1cfa08
https://doi.org/10.1136/annrheumdis-2019-eular.4137
https://doi.org/10.1136/annrheumdis-2019-eular.4137
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 10 (2019)
Frontiers in Microbiology, Vol 10 (2019)
The relentless growth of multidrug resistance and generation of recalcitrant biofilm are major obstacles in treating wounds, particularly in austere military environments where broad-spectrum pathogen coverage is needed. Designed antimicrobial peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28482f01b495969a27fe968e2340e7ea
https://pubmed.ncbi.nlm.nih.gov/31396193
https://pubmed.ncbi.nlm.nih.gov/31396193
Autor:
Lydia-Marie Joubert, Hasan Nazik, Alfred Botha, David A. Stevens, Jesse M. Jaynes, L. Edward Clemens, Kathryn W Woodburn
Publikováno v:
Antimicrobial Agents and Chemotherapy
Recurrent vulvovaginal candidiasis (RVVC) is a widespread chronic infection that has a substantial negative impact on work and quality of life. The development of antimicrobial resistance and biofilm formation are speculated to contribute to Candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea199438ce05a79ee0f7b5ad22ac2583
https://pubmed.ncbi.nlm.nih.gov/31451496
https://pubmed.ncbi.nlm.nih.gov/31451496