Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jesse M Rodriguez"'
Publikováno v:
eLife, Vol 4 (2015)
The effects of genetic variation on gene regulation in the developing mammalian embryo remain largely unexplored. To globally quantify these effects, we crossed two divergent mouse strains and asked how genotype of the mother or of the embryo drives
Externí odkaz:
https://doaj.org/article/0a8f00e5af4243c09e8a55a23aaab102
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92713 (2014)
Identity by descent (IBD) inference is the task of computationally detecting genomic segments that are shared between individuals by means of common familial descent. Accurate IBD detection plays an important role in various genomic studies, ranging
Externí odkaz:
https://doaj.org/article/1a63a283442f4dd8b107a7d8642680a0
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783642296260
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Inferring the ancestral origin of chromosomal segments in admixed individuals is key for genetic applications, ranging from analyzing population demographics and history, to mapping disease genes. Previous methods addressed ancestry inference by usin
Publikováno v:
Journal of Proteome Research. 7:300-305
Trypsin is the most commonly used enzyme in mass spectrometry for protein digestion with high substrate specificity. Many peptide identification algorithms incorporate these specificity rules as filtering criteria. A generally accepted "Keil rule" is
Autor:
Arend Sidow, Noah Spies, Cheryl L. Smith, Serafim Batzoglou, Jesse M. Rodriguez, Julie C. Baker
Publikováno v:
eLife, Vol 4 (2015)
eLife
eLife
The effects of genetic variation on gene regulation in the developing mammalian embryo remain largely unexplored. To globally quantify these effects, we crossed two divergent mouse strains and asked how genotype of the mother or of the embryo drives
Publikováno v:
Genome research. 25(2)
Identity-by-descent (IBD) inference is the problem of establishing a genetic connection between two individuals through a genomic segment that is inherited by both individuals from a recent common ancestor. IBD inference is an important preceding ste
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783642371943
RECOMB
RECOMB
Studies that map disease genes rely on accurate annotations that indicate whether individuals in the studied cohorts are related to each other or not. For example, in genome-wide association studies, the cohort members are assumed to be unrelated to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a5bc7bdd97e65b4c569588c2b4fab95
https://doi.org/10.1007/978-3-642-37195-0_18
https://doi.org/10.1007/978-3-642-37195-0_18
Autor:
Richard D. Smith, Vineet Bafna, Vipul Bhargava, Ian Kerman, Elisabeth Kain, Nitin Gupta, Jamal Benhamida, Jesse M. Rodriguez, Margaret F. Romine, Noah Ollikainen, Ngan Nguyen, Daniel B. Goodman, Pavel A. Pevzner, Mary S. Lipton, Jian Wang
Publikováno v:
Genome research. 18(7)
Recent proliferation of low-cost DNA sequencing techniques will soon lead to an explosive growth in the number of sequenced genomes and will turn manual annotations into a luxury. Mass spectrometry recently emerged as a valuable technique for proteog