Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jesse Kreger"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Clonal hematopoiesis becomes increasingly common with age, but its cause is enigmatic because driver mutations are often absent. Serial observations infer weak selection indicating variants are acquired much earlier in life with unexplained
Externí odkaz:
https://doaj.org/article/fb81658c57054a4085daf759ceb98459
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 12, p e1009713 (2021)
To study viral evolutionary processes within patients, mathematical models have been instrumental. Yet, the need for stochastic simulations of minority mutant dynamics can pose computational challenges, especially in heterogeneous systems where very
Externí odkaz:
https://doaj.org/article/2b37ac46990a482b85cdf9eb153177c2
Publikováno v:
Cancer Immunology Research. 11:614-628
Myeloid-derived suppressor cells (MDSC) play a prominent role in the tumor microenvironment. A quantitative understanding of the tumor–MDSC interactions that influence disease progression is critical, and currently lacking. We developed a mathemati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31d5370641a6a2cc76c379adb6026aab
https://doi.org/10.1158/2326-6066.cir-22-0617
https://doi.org/10.1158/2326-6066.cir-22-0617
Myeloid-derived suppressor cells (MDSC) play a prominent role in the tumor microenvironment. A quantitative understanding of the tumor–MDSC interactions that influence disease progression is critical, and currently lacking. We developed a mathemati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a7bd277468c96c398ea35eee1fe32a
https://doi.org/10.1158/2326-6066.c.6573749
https://doi.org/10.1158/2326-6066.c.6573749
Supplementary Text and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a60ac7ac1b091a1c8301ecbc5ba9c2d
https://doi.org/10.1158/2326-6066.22592858.v1
https://doi.org/10.1158/2326-6066.22592858.v1
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7652f3174bdfaaca3fbd1db83ab1e76
https://doi.org/10.1158/2326-6066.22592861
https://doi.org/10.1158/2326-6066.22592861
Autor:
Edgar Gonzalez, Adam L. MacLean, Evanthia T. Roussos Torres, Aaron Baugh, Jesse Kreger, Sofi Castanon, Valerie Narumi, Elizabeth M. Jaffee
Publikováno v:
Cancer Research. 83:3256-3256
Single agent immune checkpoint inhibitors (ICIs) are ineffective against metastatic breast cancer. One mechanism of intrinsic resistance is the presence of immunosuppressive myeloid cells and dysfunctional dendritic cells in the metastatic tumor micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a9053b63d6c61021452668bb6d19398
https://doi.org/10.1158/1538-7445.am2023-3256
https://doi.org/10.1158/1538-7445.am2023-3256
Autor:
Aaron G. Baugh, Edgar Gonzalez, Valerie H. Narumi, Sofi Castanon, Jesse Kreger, James Leatherman, Won Jin Ho, Ashley Cimino-Mathews, Vered Stearns, Roisin M. Connolly, Elizabeth M. Jaffee, Adam L. MacLean, Evanthia T. Roussos Torres
Publikováno v:
Cancer Research. 83:5167-5167
Metastatic breast cancer remains one of the leading causes of global cancer incidence in women, despite the benefit of immune checkpoint inhibitors (ICIs) in managing various cancers and improving patient quality of life. Metastatic breast cancer is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94f62929f6c533185cb8c3b0554c0f5f
https://doi.org/10.1158/1538-7445.am2023-5167
https://doi.org/10.1158/1538-7445.am2023-5167
Myeloid-derived suppressor cells (MDSCs) play a prominent and rising role in the tumor microenvironment. An understanding of the tumor-MDSC interactions that influence disease progression is critical, and currently lacking. To address this, we develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6428c811ad9fe705db05621d33e1048
https://doi.org/10.1101/2022.06.15.496246
https://doi.org/10.1101/2022.06.15.496246