Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jesse J. Parry"'
Autor:
Igor P. Dmitriev, Elena A. Kashentseva, Kenneth H. Kim, Qiana L. Matthews, Stephanie S. Krieger, Jesse J. Parry, Kim N. Nguyen, Walter J. Akers, Samuel Achilefu, Buck E. Rogers, Ronald D. Alvarez, David T. Curiel
Publikováno v:
Molecular Imaging, Vol 13 (2014)
A significant limiting factor to the human clinical application of conditionally replicative adenovirus (CRAd)-based virotherapy is the inability to noninvasively monitor these agents and their potential persistence. To address this issue, we propose
Externí odkaz:
https://doaj.org/article/11c8a7d66c1b42468dc6db1106f96ab5
Autor:
Jesse J. Parry, Martin Eiblmaier, Rebecca Andrews, Laura A. Meyer, Ryuji Higashikubo, Carolyn J. Anderson, Buck E. Rogers
Publikováno v:
Molecular Imaging, Vol 6 (2007)
Although radiolabeled somatostatin analogs have become highly prevalent in the diagnosis and treatment of somatostatin receptor subtype (sst)-positive tumors, there are relatively few options with respect to sst-positive tumor cell lines and animal m
Externí odkaz:
https://doaj.org/article/c2de35071f844073ac1ffd13c7d0c02a
Autor:
Sharlene Velichko, Alison O'Mahony, Alastair J. King, Jesse J. Parry, Justin H. Lipner, Alyssa M. Croff, Steven M. Garner
Publikováno v:
Molecular Cancer Therapeutics. 18:C116-C116
Although recent innovations in anti-cancer therapies have led to better treatment strategies and improved patient outcomes, cancer is still one of the leading causes of morbidity and mortality, globally. Thus, the need to pursue better and safer ther
Autor:
Hairong Li, Amit V. Desai, Joseph Whittenberg, Jesse J. Parry, Buck E. Rogers, Haiying Zhou, Stephanie Krieger, David E. Reichert, Paul J. A. Kenis
Publikováno v:
Bioconjugate Chemistry
This study was aimed at developing a triazine-based modular platform for targeted PET imaging. We synthesized mono- or bis-cyclo(RGDfK) linked triazine-based conjugates specifically targeting integrin αvβ3 receptors. The core molecules could be eas
Autor:
Alastair J. King, Natiya E. Robinson, Kayla A. Stehle, Steven M. Garner, Jesse J. Parry, Vanessa L. Norman, Kristin C. Dempsey, Joseph W. Murphy, Charles R. Wageman, Alyssa M. Croff, Lee R. Cavedine, Tracy Lu, Brogan A. Epkins, Victoria V. McBain
Publikováno v:
Cancer Research. 79:2073-2073
Oncology drugs with clinical utility for the treatment of breast cancer span a wide range of different mechanisms and cancer type profiles. Anti-cancer therapies have come a long way from the early use of broad spectrum, cytotoxic agents, with mechan
Autor:
Tracy Lu, Vanessa L. Norman, Lee R. Cavedine, Kayla A. Stehle, Steven M. Garner, Natiya E. Robinson, Alyssa M. Croff, Jesse J. Parry, Victoria V. McBain, Kristin C. Dempsey, Joseph T. Murphy, Charles R. Wageman, Brogan A. Epkins, Alastair J. King
Publikováno v:
Cancer Research. 79:4245-4245
High-throughput, cell-based drug screening platforms are essential to guiding drug discovery programs and can rapidly generate large amounts of pharmacological information about a candidate drug. Drug response data combined with genomic and phenotypi
Publikováno v:
Journal of Nuclear Medicine. 54:1621-1629
Radioimmunotherapy has been successfully used in the treatment of lymphoma but thus far has not demonstrated significant efficacy in humans beyond disease stabilization in solid tumors. Radioimmunotherapy with (64)Cu was highly effective in a hamster
Autor:
Ron Chen, Samuel Achilefu, W. Barry Edwards, Buck E. Rogers, Issam El Naqa, Mikhail Y. Berezin, Jesse J. Parry, Walter J. Akers
Publikováno v:
Journal of Nuclear Medicine. 51:1456-1463
Gene therapy trials have traditionally used tumor and tissue biopsies for assessing the efficacy of gene transfer. Noninvasive imaging techniques offer a distinct advantage over tissue biopsies in that the magnitude and duration of gene transfer can
Autor:
Natiya E. Robinson, Alyssa M. Croff, Vanessa L. Norman, Alastair J. King, Brogan A. Epkins, Lee R. Cavedine, Steven M. Garner, Jesse J. Parry, Kristin C. Dempsey, Charles R. Wageman, Usha Warrior
Publikováno v:
Cancer Research. 78:2260-2260
Using drug response data, generated by the OncoPanelTM cell-based profiling service, we investigated the differences between traditional and normalized growth rate inhibition (GR) metrics in drug sensitivity classification and predictive genomic biom
Autor:
Usha Warrior, Timothy J. Sindelar, Natiya E. Robinson, Vanessa L. Norman, Kristin C. Dempsey, Brogan A. Epkins, Alastair J. King, Charles R. Wageman, Lee R. Cavedine, Steven M. Garner, Jesse J. Parry, Alyssa M. Croff
Publikováno v:
Cancer Research. 78:1391-1391
Given the importance and significance of targeting mutations and epigenetic modification in cancer therapy, we sought to expand on our ability to test drugs with epigenetic modulatory abilities by increasing the exposure time of drugs against cell li