Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jesse G Toe"'
Autor:
Adam K Wheatley, Marit Kramski, Marina R Alexander, Jesse G Toe, Rob J Center, Damian F J Purcell
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18225 (2011)
Small non-coding micro-RNAs (miRNA) are important post-transcriptional regulators of mammalian gene expression that can be used to direct the knockdown of expression from targeted genes. We examined whether DNA vaccine vectors co-expressing miRNA wit
Externí odkaz:
https://doaj.org/article/9db7995f291e4ccbaef92482bf184add
Autor:
Timothy W. Schacker, Axel Kallies, Heather M. Long, Zhaohua Hou, Yong Tao, Claire Deleage, Martina Minnich, Iain Comerford, Meinrad Busslinger, Yew Ann Leong, Benjamin J Meckiff, Greg J. Beilman, Lei Sun, Simon Preston, Yunbo Wei, Anurag Atnerkar, Yaping Chen, Marc Pellegrini, Kevin A. Fenix, Hong Sheng Ong, Jacob D. Estes, Shaun R. McColl, Di Wu, Hao K. Lu, Cody C. Allison, Umaimainthan Palendira, Di Yu, Peng Wang, Alan L. Landay, Jiawei Xu, Dimitra Zotos, Jesse G. Toe, Sharon R Lewin, Jeffrey G. Chipman, Gabrielle T. Belz, Alexander L. Dent, Kevin Man
Publikováno v:
Nature Immunology. 17:1187-1196
During unresolved infections, some viruses escape immunological control and establish a persistant reservoir in certain cell types, such as human immunodeficiency virus (HIV), which persists in follicular helper T cells (TFH cells), and Epstein-Barr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6c368c40cb1e6f3ad94d066a3da1d9
https://doi.org/10.1038/ni.3543
https://doi.org/10.1038/ni.3543
Autor:
Gregor Ebert, Jesse G. Toe, Ruth Chin, C. Glenn Begley, Nadia Warner, Simon Preston, Xin Li, John Silke, Joseph Torresi, Peter Revill, Marc Pellegrini, James P Cooney, Samar Ojaimi, Michael D. Stutz, Cody C. Allison, Hamish W Scott, Danielle Colledge, Ueli Nachbur, Scott Bowden, Nikola Baschuk
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Hepatitis B virus (HBV) infection can result in a spectrum of outcomes from immune-mediated control to disease progression, cirrhosis, and liver cancer. The host molecular pathways that influence and contribute to these outcomes need to be defined. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c97f21723068a3d29333f92d8660a8a
Autor:
Simon Preston, Yongkai Ow, Jesse G. Toe, Amy E. Lin, Hamish W Scott, Andrew Wakeham, Tak W. Mak, James P Cooney, Gregor Ebert, Jennifer Silvester, Raymond H. Kim, Samuel D. Saibil, Pamela S. Ohashi, Annick You-Ten, Arda Shahinian, Marc Pellegrini, Masato Sasaki, Dilan Dissanayake, Gordon S. Duncan
Publikováno v:
Nature Immunology. 14:27-33
The E3 ligase ARIH2 has an unusual structure and mechanism of elongating ubiquitin chains. To understand its physiological role, we generated gene-targeted mice deficient in ARIH2. ARIH2 deficiency resulted in the embryonic death of C57BL/6 mice. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005aa4b604cac400cdcafed12bf6cb75
https://doi.org/10.1038/ni.2478
https://doi.org/10.1038/ni.2478
Autor:
Jesse G. Toe, Joanne A. O’Donnell, Donald Metcalf, Hiu Kiu, Warren S. Alexander, Simon P. Preston, Kate McArthur, Andrew W. Roberts, Marc Pellegrini, Louise H. Cengia, Nicos A. Nicola, Ben A. Croker
Publikováno v:
Immunology and cell biology
The lack of expression of the suppressor of cytokine signalling-3 (SOCS3) or inactivation of the negative regulatory capacity of SOCS3 has been well documented in rheumatoid arthritis, viral hepatitis and cancer. The specific qualitative and quantita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b92bfe9a374c2b5b204d9ebf7048787
https://doi.org/10.1038/icb.2011.29
https://doi.org/10.1038/icb.2011.29
Autor:
Joseph Torresi, James P Cooney, Marc Pellegrini, Gregor Ebert, Cody C. Allison, Simon Preston, Samar Ojaimi, John Silke, Jesse G. Toe, Michael D. Stutz, Ueli Nachbur, Nikola Baschuk, C. Glenn Begley
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
We have shown that cellular inhibitor of apoptosis proteins (cIAPs) impair clearance of hepatitis B virus (HBV) infection by preventing TNF-mediated killing/death of infected cells. A key question, with profound therapeutic implications, is whether t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0194f978622813dfcb2552766c8c0dab
https://pubmed.ncbi.nlm.nih.gov/25902530
https://pubmed.ncbi.nlm.nih.gov/25902530
Publikováno v:
Molecular immunology. 56(1-2)
The continued global burden wrought by chronic infectious disease is unrelenting. Current therapies have curbed the severity of disease for patients, but Human Immunodeficiency Virus (HIV) and Hepatitis B (HBV) infection remain incurable and Mycobact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1b0d969187c68ae415e2426e6d21c5
https://pubmed.ncbi.nlm.nih.gov/23685259
https://pubmed.ncbi.nlm.nih.gov/23685259
Autor:
Katharina Lahl, Arda Shahinian, Thomas F. Tedder, Marc Pellegrini, Philipp A. Lang, Brigitte Assouline, Sameh Basta, Alisha R. Elford, Simon P. Preston, Tak W. Mak, Amy E. Lin, Michel Morre, Jihye Paik, Ronald A. DePinho, Jesse G. Toe, Thomas Calzascia, Karl S. Lang, Tim Sparwasser, Pamela S. Ohashi
Publikováno v:
Cell. 144(4)
SummaryUnderstanding the factors that impede immune responses to persistent viruses is essential in designing therapies for HIV infection. Mice infected with LCMV clone-13 have persistent high-level viremia and a dysfunctional immune response. Interl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3212eca6f8fc4cdc9d0bd8ab27f38b
https://pubmed.ncbi.nlm.nih.gov/21456116
https://pubmed.ncbi.nlm.nih.gov/21456116