Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jesse Engreitz"'
Autor:
Farhad Hormozdiari, Bryce van de Geijn, Joseph Nasser, Omer Weissbrod, Steven Gazal, Chelsea J. -T. Ju, Luke O’ Connor, Margaux L. A. Hujoel, Jesse Engreitz, Fereydoun Hormozdiari, Alkes L. Price
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Transposable elements (TE) make up a large component of the human genome and have been shown to contribute to human diseases. Here, Hormozdiari et al. estimate the contribution of TEs to the heritability of 41 complex traits and diseases and find enr
Externí odkaz:
https://doaj.org/article/2162e007b86c49c889aa730a2d6a4779
Autor:
Seyedeh M. Zekavat, Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver, Jonathan Bloom, Timothy Poterba, Cotton Seed, Jason Ernst, Mark Chaffin, Jesse Engreitz, Gina M. Peloso, Ani Manichaikul, Chaojie Yang, Kathleen A. Ryan, Mao Fu, W. Craig Johnson, Michael Tsai, Matthew Budoff, Ramachandran S. Vasan, L. Adrienne Cupples, Jerome I. Rotter, Stephen S. Rich, Wendy Post, Braxton D. Mitchell, Adolfo Correa, Andres Metspalu, James G. Wilson, Veikko Salomaa, Manolis Kellis, Mark J. Daly, Benjamin M. Neale, Steven McCarroll, Ida Surakka, Tonu Esko, Andrea Ganna, Samuli Ripatti, Sekar Kathiresan, Pradeep Natarajan, NHLBI TOPMed Lipids Working Group
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Circulating lipoprotein(a) is an important risk factor for cardiovascular disease and shows variability between different ethnic groups. Here, Zekavat et al. perform whole-genome sequencing in individuals of European and African ancestries and find a
Externí odkaz:
https://doaj.org/article/dd61e81e8545472a93ddce68c769d81d
Autor:
Seyedeh M. Zekavat, Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver, Jonathan Bloom, Timothy Poterba, Cotton Seed, Jason Ernst, Mark Chaffin, Jesse Engreitz, Gina M. Peloso, Ani Manichaikul, Chaojie Yang, Kathleen A. Ryan, Mao Fu, W. Craig Johnson, Michael Tsai, Matthew Budoff, Ramachandran S. Vasan, L. Adrienne Cupples, Jerome I. Rotter, Stephen S. Rich, Wendy Post, Braxton D. Mitchell, Adolfo Correa, Andres Metspalu, James G. Wilson, Veikko Salomaa, Manolis Kellis, Mark J. Daly, Benjamin M. Neale, Steven McCarroll, Ida Surakka, Tonu Esko, Andrea Ganna, Samuli Ripatti, Sekar Kathiresan, Pradeep Natarajan, NHLBI TOPMed Lipids Working Group
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-3 (2018)
The original version of this article contained an error in the name of the author Ramachandran S. Vasan, which was incorrectly given as Vasan S. Ramachandran. This has now been corrected in both the PDF and HTML versions of the article.
Externí odkaz:
https://doaj.org/article/ed98c5cbb85047639d47b9dbdb629fac
Autor:
Seyedeh M. Zekavat, Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver, Jonathan Bloom, Timothy Poterba, Cotton Seed, Jason Ernst, Mark Chaffin, Jesse Engreitz, Gina M. Peloso, Ani Manichaikul, Chaojie Yang, Kathleen A. Ryan, Mao Fu, W. Craig Johnson, Michael Tsai, Matthew Budoff, Ramachandran S. Vasan, L. Adrienne Cupples, Jerome I. Rotter, Stephen S. Rich, Wendy Post, Braxton D. Mitchell, Adolfo Correa, Andres Metspalu, James G. Wilson, Veikko Salomaa, Manolis Kellis, Mark J. Daly, Benjamin M. Neale, Steven McCarroll, Ida Surakka, Tonu Esko, Andrea Ganna, Samuli Ripatti, Sekar Kathiresan, Pradeep Natarajan, NHLBI TOPMed Lipids Working Group
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/87e748518844422fb76a84381bad8336
Autor:
Ashwin R. Iyer, Aishwarya Gurumurthy, Rohan Kodgule, Athalee R. Aguilar, Travis Saari, Abdullah Ramzan, Dylan Rausch, Juhi Gupta, Cody N. Hall, John S. Runge, Matthew Weiss, Mahshid Rahmat, Rockwell Anyoha, Charles P. Fulco, Irene M. Ghobrial, Jesse Engreitz, Marcin P. Cieslik, Russell J.H. Ryan
Publikováno v:
bioRxiv
High expression ofMYCand its target genes define a subset of germinal center B-cell diffuse large B-cell lymphoma (GCB-DLBCL) associated with poor outcomes. Half of these high-grade cases show chromosomal rearrangements between theMYClocus and hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842ac2fa950f60ae4ea709ef5d5410fb
https://doi.org/10.1101/2023.05.02.538892
https://doi.org/10.1101/2023.05.02.538892
Autor:
Mengyao Yu, Andrew R. Harper, Matthew Aguirre, Maureen Pittman, Catherine Tcheandjieu, Dulguun Amgalan, Christopher Grace, Anuj Goel, Martin Farrall, Ke Xiao, Jesse Engreitz, Katherine S. Pollard, Hugh Watkins, James R. Priest
Publikováno v:
Circulation: Genomic and Precision Medicine.
Background: A large proportion of genetic risk remains unexplained for structural heart disease involving the interventricular septum (IVS) including hypertrophic cardiomyopathy and ventricular septal defects. This study sought to develop a reproduci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::306f5a3124f179cb9998aad598f681ee
https://doi.org/10.1161/circgen.122.003708
https://doi.org/10.1161/circgen.122.003708
Autor:
Henri Schmidt, Michael A Beer, Steven Reilly, Benjamin Doughty, Lexi Bounds, Ava Mackay-Smith, Jesse Engreitz
The ENCODE Consortium’s efforts to annotate non-coding,cis-regulatory elements (CREs) have advanced our understanding of gene regulatory landscapes which play a major role in health and disease. Pooled, non-coding CRISPR screens are a promising app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f0b8f04937c4211b118285a782c4c4
https://doi.org/10.1101/2022.12.21.520137
https://doi.org/10.1101/2022.12.21.520137
Autor:
Mohamed Ameen, Laksshman Sundaram, Abhimanyu Banerjee, Mengcheng Shen, Soumya Kundu, Surag Nair, Anna Shcherbina, Mingxia Gu, Kitchener D. Wilson, Avyay Varadarajan, Nirmal Vadgama, Akshay Balsubramani, Joseph C. Wu, Jesse Engreitz, Kyle Farh, Ioannis Karakikes, Kevin C Wang, Thomas Quertermous, William Greenleaf, Anshul Kundaje
Publikováno v:
Cell. 185:4937-4953.e23
SummaryCongenital heart defects, the most common birth disorders, are the clinical manifestation of anomalies in fetal heart development - a complex process involving dynamic spatiotemporal coordination among various precursor cell lineages. This com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da875171c65924d167d1a14f2f926ed
https://doi.org/10.1016/j.cell.2022.11.028
https://doi.org/10.1016/j.cell.2022.11.028
Autor:
Mengyao Yu, Andrew Harper, Matthew Aguirre, Maureen Pittman, Catherine Tcheandjieu, Dulguun Amgalan, Christopher Grace, Anuj Goel, Martin Farrall, Ke Xiao, Jesse Engreitz, Katherine Pollard, Hugh C Watkins, James R Priest
Publikováno v:
Circulation. 144
Background: A large proportion of genetic risk remains unexplained for structural heart disease involving the interventricular septum (IVS) including hypertrophic cardiomyopathy (HCM) and ventricular septal defects (VSD). Methods: We performed machin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91ea45b68fd65700663d1ca2a4cd0e42
https://doi.org/10.1161/circ.144.suppl_1.11789
https://doi.org/10.1161/circ.144.suppl_1.11789
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1262
RNA-centric biochemical purification is a general approach for studying the functions and mechanisms of noncoding RNAs. Here, we describe the experimental procedures for RNA antisense purification (RAP), a method for selective purification of endogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2088fc3fa087e803d3af9823eb20326f
https://pubmed.ncbi.nlm.nih.gov/25555582
https://pubmed.ncbi.nlm.nih.gov/25555582