Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jesse D Martinez"'
Publikováno v:
BioTechniques, Vol 66, Iss 5, Pp 214-217 (2019)
Micro-computed tomography (micro-CT) coupled with tissue, or vascular, specific contrast agent has emerged as a powerful tool for detecting and monitoring tumor growth in the liver of murine animals. Intravenous injections of contrast agents can be t
Externí odkaz:
https://doaj.org/article/e5dbd14aeb1b498e8ed7f24fff74c371
Autor:
Diana J Uribe, Edward K Mandell, Adam Watson, Jesse D Martinez, Jonathan A Leighton, Sourav Ghosh, Carla V Rothlin
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179979 (2017)
The receptor tyrosine kinases (RTKs) TYRO3, AXL and MERTK (TAM) have well-described oncogenic functions in a number of cancers. Notwithstanding, TAM RTKs are also potent and indispensable inhibitors of inflammation. The combined deletion of Axl and M
Externí odkaz:
https://doaj.org/article/d5f73fbd5390456c828b1d487687d6ba
Autor:
Vijayababu M Radhakrishnan, Pawel Kojs, Gavin Young, Rajalakshmy Ramalingam, Bhumasamudram Jagadish, Eugene A Mash, Jesse D Martinez, Fayez K Ghishan, Pawel R Kiela
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85796 (2014)
Cortactin (CTTN), first identified as a major substrate of the Src tyrosine kinase, actively participates in branching F-actin assembly and in cell motility and invasion. CTTN gene is amplified and its protein is overexpressed in several types of can
Externí odkaz:
https://doaj.org/article/b105be6e7fb24e019de66c1e86021584
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11433 (2010)
The 14-3-3 proteins are a set of highly conserved scaffolding proteins that have been implicated in the regulation of a variety of important cellular processes such as the cell cycle, apoptosis and mitogenic signaling. Recent evidence indicates that
Externí odkaz:
https://doaj.org/article/5745c8cfbe49487bb7495c9763b65c7f
Autor:
Damian J. Junk, Lukas Vrba, George S. Watts, Marc M. Oshiro, Jesse D. Martinez, Bernard W. Futscher
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 5, Pp 450-461 (2008)
Aberrations of p53 occur in most, if not all, human cancers. In breast cancer, p53 mutation is the most common genetic defect related to a single gene. Immortalized human mammary epithelial cells resemble the earliest forms of aberrant breast tissue
Externí odkaz:
https://doaj.org/article/cb6e45f5639d466babf96d90300d23c2
Publikováno v:
Cell Division, Vol 13, Iss 1, Pp 1-10 (2018)
Cell Division
Cell Division
Background Live-cell fluorescence microscopy (LCFM) is a powerful tool used to investigate cellular dynamics in real time. However, the capacity to simultaneously measure DNA content in cells being tracked over time remains challenged by dye-associat
Autor:
Sara M. Centuori, Charles W. Putnam, Cecil J. Gomes, Michael W. Harman, Charles W. Wolgemuth, Jesse D. Martinez
Publikováno v:
Genes & Cancer
Several studies have demonstrated that specific 14-3-3 isoforms are frequently elevated in cancer and that these proteins play a role in human tumorigenesis. 14-3-3γ, an isoform recently demonstrated to function as an oncoprotein, is overexpressed i
Publikováno v:
Innovative Higher Education. 42:421-435
Universities are under pressure to increase external research funding, and some federal agencies offer programs to expand research capacity in certain kinds of institutions. However, conflicts within faculty roles and other aspects of university oper
Autor:
Nathan W, Sweeney, Cecil J, Gomes, Richard, De Armond, Sara M, Centuori, Sairam, Parthasarathy, Jesse D, Martinez
Publikováno v:
Hypoxia
Purpose Nonalcoholic fatty liver disease (NAFLD) is considered the most common form of silent liver disease in the United States and obesity is associated with increased risk of NAFLD. Obstructive sleep apnea (OSA) which is common in obese individual
Autor:
Changming Fang, Ornella I. Selmin, Peter Lance, Jesse D. Martinez, Jeffrey W. Smith, Patricia A. Thompson, Adam M. Lyon, Thomas Doetschman, Donato F. Romagnolo
Publikováno v:
The Journal of Nutrition. 146:236-242
Background The farnesoid X receptor (FXR) regulates bile acid (BA) metabolism and possesses tumor suppressor functions. FXR expression is reduced in colorectal tumors of subjects carrying inactivated adenomatous polyposis coli (APC). Identifying the