Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jesse Coward"'
Autor:
Tobias M. Hohl, Shinobu Saijo, Eric G. Pamer, Yoichiro Iwakura, Alena M. Gallegos, Jesse Coward, Ingrid Leiner, Amariliz Rivera, Nichole Collins
Publikováno v:
The Journal of Experimental Medicine
By modifying dendritic cell cytokine production, Dectin-1 suppresses Th1 differentiation in mice infected with the fungal pathogen Aspergillus fumigatus.
Pulmonary infection of mice with Aspergillus fumigatus induces concurrent T helper type 1 (
Pulmonary infection of mice with Aspergillus fumigatus induces concurrent T helper type 1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cf36cac181e156d4f406965f5eba98
https://doi.org/10.1084/jem.20100906
https://doi.org/10.1084/jem.20100906
The T cell receptor (TCR) is responsible for discriminating between self- and foreign-derived peptides, translating minute differences in amino-acid sequence into large differences in response. Because of the great variability in the TCR and its liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b1593bbb503857fb6cad8df0b117a4
https://europepmc.org/articles/PMC2869519/
https://europepmc.org/articles/PMC2869519/
Autor:
Karen E Tkach, Thierry Emonet, Jesse Coward, Kendall A. Smith, Michael W. Sneddon, Garrit Jentsch, Grégoire Altan-Bonnet, Ofer Feinerman, Matthew M Hathorn
Publikováno v:
Molecular Systems Biology
The sensitivity of T cells to interleukin-2 (IL-2) can vary by three orders of magnitude and is determined by the surface densities of the IL-2 receptor α subunits. Regulatory T cells inflict a double hit on effector T cells by lowering the bulk IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04b7f36b9dd5a6ae548c342da934477
https://pubmed.ncbi.nlm.nih.gov/21119631
https://pubmed.ncbi.nlm.nih.gov/21119631
Autor:
Grazia Ambrosini, Jayasree S. Nair, Alan L. Ho, Haider Cheema, Jesse Coward, Gary K. Schwartz, Archie N. Tse, Nicholas Keen
Publikováno v:
Molecular biology of the cell. 20(8)
The phenotypic change characteristic of Aurora B inhibition is the induction of polyploidy. Utilizing specific siRNA duplexes and a selective small molecule inhibitor (AZD1152) to inhibit Aurora B activity in tumor cells, we sought to elucidate the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34d8d04673bd74dfcf982224d052ca6
https://pubmed.ncbi.nlm.nih.gov/19225156
https://pubmed.ncbi.nlm.nih.gov/19225156
Autor:
Elgilda Musi, Grazia Ambrosini, Jesse Coward, Adriana Haimovitz-Friedman, Alfred H. Merrill, Elaine Wang, Jeremy C. Allegood, Gary K. Schwartz, Jean-Philip Truman
Publikováno v:
Autophagy. 5(2)
Safingol, the synthetic L-threo-stereoisomer of endogenous (D-erythro-) sphinganine, is an inhibitor of protein kinase C and sphingosine kinase in vitro, and in some cell types has been implicated in ceramide generation and induction of apoptosis. Ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d414ec5e7f0f882729fa6eb0e3da4a38
https://pubmed.ncbi.nlm.nih.gov/19098447
https://pubmed.ncbi.nlm.nih.gov/19098447
Publikováno v:
The Journal of Immunology. 186:57.12-57.12
The single-cell resolution of flow cytometry provides a quantitative measurement of the heterogeneity of protein expression within clonal populations of cells. As the biological significance of this variability is becoming more widely appreciated, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ddc1001baef30604bf7dab7fc99e36e
https://doi.org/10.4049/jimmunol.186.supp.57.12
https://doi.org/10.4049/jimmunol.186.supp.57.12