Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jesse Connell"'
Autor:
Lindsey J. Plenderleith, Weimin Liu, Yingying Li, Dorothy E. Loy, Ewan Mollison, Jesse Connell, Ahidjo Ayouba, Amandine Esteban, Martine Peeters, Crickette M. Sanz, David B. Morgan, Nathan D. Wolfe, Markus Ulrich, Andreas Sachse, Sébastien Calvignac-Spencer, Fabian H. Leendertz, George M. Shaw, Beatrice H. Hahn, Paul M. Sharp
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Plasmodium malariae is a cause of malaria in humans and related species have been identified in non-human primates. Here, the authors use genomic analyses to establish that human P. malariae arose from a host switch of an ape parasite whilst a specie
Externí odkaz:
https://doaj.org/article/fb4e602288f4471d94b66c97f143695e
Autor:
Emily E. Wroblewski, Lisbeth A. Guethlein, Aaron G. Anderson, Weimin Liu, Yingying Li, Sara E. Heisel, Andrew Jesse Connell, Jean-Bosco N. Ndjango, Paco Bertolani, John A. Hart, Terese B. Hart, Crickette M. Sanz, David B. Morgan, Martine Peeters, Paul M. Sharp, Beatrice H. Hahn, Peter Parham
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
A variant of MHC class I is protective against severe malaria disease and enriched in affected African populations. Here, Wroblewski et al., characterise the consequences of malaria infection in wild bonobo populations showing that the presence of ma
Externí odkaz:
https://doaj.org/article/528a72be56a540989e1b30f98ac36d3f
Autor:
Frederic Bibollet-Ruche, Ronnie M. Russell, Wenge Ding, Weimin Liu, Yingying Li, Kshitij Wagh, Daniel Wrapp, Rumi Habib, Ashwin N. Skelly, Ryan S. Roark, Scott Sherrill-Mix, Shuyi Wang, Juliette Rando, Emily Lindemuth, Kendra Cruickshank, Younghoon Park, Rachel Baum, John W. Carey, Andrew Jesse Connell, Hui Li, Elena E. Giorgi, Ge S. Song, Shilei Ding, Andrés Finzi, Amanda Newman, Giovanna E. Hernandez, Emily Machiele, Derek W. Cain, Katayoun Mansouri, Mark G. Lewis, David C. Montefiori, Kevin J. Wiehe, S. Munir Alam, I-Ting Teng, Peter D. Kwong, Raiees Andrabi, Laurent Verkoczy, Dennis R. Burton, Bette T. Korber, Kevin O. Saunders, Barton F. Haynes, Robert J. Edwards, George M. Shaw, Beatrice H. Hahn
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT HIV-1 and its SIV precursors share a broadly neutralizing antibody (bNAb) epitope in variable loop 2 (V2) at the envelope glycoprotein (Env) trimer apex. Here, we tested the immunogenicity of germ line-targeting versions of a chimpanzee SIV
Externí odkaz:
https://doaj.org/article/3b93383f6dad4c28967afedad78671dd
Autor:
Franziska Trede, Niels Kil, James Stranks, Andrew Jesse Connell, Julia Fischer, Julia Ostner, Oliver Schülke, Dietmar Zinner, Christian Roos
Publikováno v:
Ecology and Evolution, Vol 11, Iss 1, Pp 498-505 (2021)
Abstract Microsatellite genotyping is an important genetic method for a number of research questions in biology. Given that the traditional fragment length analysis using polyacrylamide gel or capillary electrophoresis has several drawbacks, microsat
Externí odkaz:
https://doaj.org/article/ad573acc5b9f40e7a563bf8a4515ec68
Autor:
Erik L. Clarke, A. Jesse Connell, Emmanuelle Six, Nadia A. Kadry, Arwa A. Abbas, Young Hwang, John K. Everett, Casey E. Hofstaedter, Rebecca Marsh, Myriam Armant, Judith Kelsen, Luigi D. Notarangelo, Ronald G. Collman, Salima Hacein-Bey-Abina, Donald B. Kohn, Marina Cavazzana, Alain Fischer, David A. Williams, Sung-Yun Pai, Frederic D. Bushman
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background Mutation of the IL2RG gene results in a form of severe combined immune deficiency (SCID-X1), which has been treated successfully with hematopoietic stem cell gene therapy. SCID-X1 gene therapy results in reconstitution of the prev
Externí odkaz:
https://doaj.org/article/3e61033ef32c4bfb98b5c61714518c31
Autor:
Hannah J. Barbian, Andrew Jesse Connell, Alexa N. Avitto, Ronnie M. Russell, Andrew G. Smith, Madhurima S. Gundlapally, Alexander L. Shazad, Yingying Li, Frederic Bibollet‐Ruche, Emily E. Wroblewski, Deus Mjungu, Elizabeth V. Lonsdorf, Fiona A. Stewart, Alexander K. Piel, Anne E. Pusey, Paul M. Sharp, Beatrice H. Hahn
Publikováno v:
Ecology and Evolution, Vol 8, Iss 16, Pp 7946-7963 (2018)
Abstract Short tandem repeats (STRs), also known as microsatellites, are commonly used to noninvasively genotype wild‐living endangered species, including African apes. Until recently, capillary electrophoresis has been the method of choice to dete
Externí odkaz:
https://doaj.org/article/1eb63431f6a14f08bdd03d0f9ed1ed4c
Autor:
Frederic Bibollet-Ruche, Ronnie M. Russell, Wenge Ding, Weimin Liu, Yingying Li, Kshitij Wagh, Daniel Wrapp, Rumi Habib, Ashwin N. Skelly, Ryan S. Roark, Scott Sherrill-Mix, Shuyi Wang, Juliette Rando, Emily Lindemuth, Kendra Cruickshank, Younghoon Park, Rachel Baum, Andrew Jesse Connell, Hui Li, Elena E. Giorgi, Ge S. Song, Shilei Ding, Andrés Finzi, Amanda Newman, Giovanna E. Hernandez, Emily Machiele, Derek W. Cain, Katayoun Mansouri, Mark G. Lewis, David C. Montefiori, Kevin J. Wiehe, S. Munir Alam, I-Ting Teng, Peter D. Kwong, Raiees Andrabi, Laurent Verkoczy, Dennis R. Burton, Bette T. Korber, Kevin O. Saunders, Barton F. Haynes, Robert J. Edwards, George M. Shaw, Beatrice H. Hahn
HIV-1 and its SIV precursors share a broadly neutralizing antibody (bNAb) epitope in variable loop 2 (V2) at the envelope glycoprotein (Env) trimer apex. Here, we tested the immunogenicity of germline-targeting versions of a chimpanzee SIV (SIVcpz) E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4718402789a3f8c350c9c54348a49e4b
https://doi.org/10.1101/2022.10.18.512699
https://doi.org/10.1101/2022.10.18.512699
Autor:
Lindsey J, Plenderleith, Weimin, Liu, Yingying, Li, Dorothy E, Loy, Ewan, Mollison, Jesse, Connell, Ahidjo, Ayouba, Amandine, Esteban, Martine, Peeters, Crickette M, Sanz, David B, Morgan, Nathan D, Wolfe, Markus, Ulrich, Andreas, Sachse, Sébastien, Calvignac-Spencer, Fabian H, Leendertz, George M, Shaw, Beatrice H, Hahn, Paul M, Sharp
Publikováno v:
Nature communications. 13(1)
The human parasite Plasmodium malariae has relatives infecting African apes (Plasmodium rodhaini) and New World monkeys (Plasmodium brasilianum), but its origins remain unknown. Using a novel approach to characterise P. malariae-related sequences in
Autor:
Preston A. Marx, William J. Kohler, Sandrine François-Souquiere, Alexander V. Georgiev, Weimin Liu, Ronnie M. Russell, Stephanie Trimboli, Scott Sherrill-Mix, Ronald G. Collman, Beatrice H. Hahn, Paul M. Sharp, Alex K. Piel, Paco Bertolani, Martine Peeters, Dorothy E. Loy, Marcos V. P. Gondim, Ahidjo Ayouba, Amandine Esteban, George M. Shaw, Lindsey J. Plenderleith, Volker Sommer, Frederic Bibollet-Ruche, Jesse Connell, Terese B. Hart, Fiona A. Stewart, Andrew G. Smith, Vanessa M. Hirsch, William M. Switzer, John Hart, Alexa N. Avitto, Katherine S. Wetzel, Yingying Li, Richard A. Miller
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Russell, R M, Bibollet-Ruche, F, Liu, W, Sherrill-Mix, S, Li, Y, Connell, J, Loy, D E, Trimboli, S, Smith, A G, Avitto, A N, Gondim, M V P, Plenderleith, L J, Wetzel, K S, Collman, R G, Ayouba, A, Esteban, A, Peeters, M, Kohler, W J, Miller, R A, François-Souquiere, S, Switzer, W M, Hirsch, V M, Marx, P A, Piel, A K, Stewart, F A, Georgiev, A V, Sommer, V, Bertolani, P, Hart, J A, Hart, T B, Shaw, G M, Sharp, P M & Hahn, B H 2021, ' CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses ', Proceedings of the National Academy of Sciences, vol. 118, no. 13, e2025914118 . https://doi.org/10.1073/pnas.2025914118
Russell, R M, Bibollet-Ruche, F, Liu, W, Sherrill-Mix, S, Li, Y, Connell, J, Loy, D E, Trimboli, S, Smith, A G, Avitto, A N, Gondim, M V P, Plenderleith, L J, Wetzel, K S, Collman, R G, Ayouba, A, Esteban, A, Peeters, M, Kohler, W J, Miller, R A, François-Souquiere, S, Switzer, W M, Hirsch, V M, Marx, P A, Piel, A K, Stewart, F A, Georgiev, A V, Sommer, V, Bertolani, P, Hart, J A, Hart, T B, Shaw, G M, Sharp, P M & Hahn, B H 2021, ' CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses ', Proceedings of the National Academy of Sciences, vol. 118, no. 13, e2025914118 . https://doi.org/10.1073/pnas.2025914118
Significance The CD4 protein of primates has undergone rapid diversification, but the reasons for this remain unknown. Here we show that within-species diversity of the HIV/simian immunodeficiency virus (SIV) envelope (Env) binding (D1) domain is com
Autor:
Robert F. Siliciano, Weimin Liu, Alexa N. Avitto, Michel C. Nussenzweig, Yehuda Z. Cohen, Paul M. Sharp, Michael S. Saag, Ronnie M. Russell, Luis J. Montaner, Frederic Bibollet-Ruche, Ronald G. Collman, George M. Shaw, Pierre Pellegrino, Sonya L. Heath, Julio C. C. Lorenzi, Jesse Connell, Ian Williams, Stephanie Trimboli, Andrew G. Smith, M. Alexandra Monroy, Scott Sherrill-Mix, Yingying Li, Beatrice H. Hahn, Janet M. Siliciano, D. Brenda Salantes, Lindsey J. Plenderleith, Emmanouil Papasavvas, Angharad E. Fenton-May, Julia DeVoto, Katharine J. Bar, Marina Caskey, Marcos V. P. Gondim, Persephone Borrow, Felicity Mampe
Publikováno v:
Gondim, M V P, Sherrill-Mix, S, Bibollet-Ruche, F, Russell, R M, Trimboli, S, Smith, A G, Li, Y, Liu, W, Avitto, A N, DeVoto, J C, Connell, J, Fenton-May, A E, Pellegrino, P, Williams, I, Papasavvas, E, Lorenzi, J C C, Brenda Salantes, D, Mampe, F, Alexandra Monroy, M, Cohen, Y Z, Heath, S, Saag, M S, Montaner, L J, Collman, R G, Siliciano, J M, Siliciano, R F, Plenderleith, L J, Sharp, P M, Caskey, M, Nussenzweig, M C, Shaw, G M, Borrow, P, Bar, K J & Hahn, B H 2021, ' Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption ', Science Translational Medicine, vol. 13, no. 576, eabd8179 . https://doi.org/10.1126/SCITRANSLMED.ABD8179
Sci Transl Med
Sci Transl Med
Type 1 interferons (IFN-I) are potent innate antiviral effectors that constrain HIV-1 transmission. However, harnessing these cytokines for HIV-1 cure strategies has been hampered by an incomplete understanding of their antiviral activities at later
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd61e6b06a1340de5cdaf3c9a30f3230
https://hdl.handle.net/20.500.11820/a6051f01-6cf5-434d-b22c-8486e3fd60c2
https://hdl.handle.net/20.500.11820/a6051f01-6cf5-434d-b22c-8486e3fd60c2