Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jesse Chung-Sean Pang"'
Autor:
Yu Yao, Aden Ka-Yin Chan, Zhi Yong Qin, Ling Chao Chen, Xin Zhang, Jesse Chung-Sean Pang, Hiu Ming Li, Yin Wang, Ying Mao, Ho-Keung Ng, Liang Fu Zhou
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67421 (2013)
Recurrence and progression to higher grade lesions are characteristic behaviors of gliomas. Though IDH1 mutation frequently occurs and is considered as an early event in gliomagenesis, little is known about its role in the recurrence and progression
Externí odkaz:
https://doaj.org/article/9d9aaf893b9d4eb29b225434fa808bac
Autor:
Alfred S. L. Cheng, Joanna H.M. Tong, Feng Wu, Jun Yu, Jinglin Zhang, Yuhang Zhou, Yi Pan, Yujuan Dong, Chi Chun Wong, Jesse Chung Sean Pang, Ka Fai To, Anthony W.H. Chan, Raymond W.M. Lung, Wei Kang, Shiyan Wang, Tingting Huang, Bin Zhang, Wing Po Chak, Weiqin Yang, Alvin Ho-Kwan Cheung
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 2, Pp 1-16 (2018)
Cell Death and Disease, Vol 9, Iss 2, Pp 1-16 (2018)
miR-375 is a tumor-suppressive microRNA (miRNA) in gastric cancer (GC). However, its molecular mechanism remains unclear. The aim of this study is to comprehensively investigate how miR-375 is involved in Hippo pathway by targeting multiple oncogenes
Autor:
Yong Ren, Xiao-Peng Zhu, Ya-Wen Pan, Qing-Fu Xu, Zheng Zhou, Hiroko Ohgaki, Li-Chao Li, Hui Yang, Jesse Chung Sean Pang, Sheng-Qing Lv, Qi-Lin Huang
Publikováno v:
Brain Pathology. 24:568-583
Medulloblastoma is the most frequent malignant central nervous system tumor in children. MicroRNAs (miRs) are small, non-coding RNAs that target protein-coding and non-coding RNAs, and play roles in a variety of cellular processes through regulation
Autor:
Ho Keung Ng, Aij Lie Kwan, Fu Rong Chen, Zhong Ping Chen, Qun Ying Yang, Ke Sai, Jesse Chung Sean Pang, Jun Fu
Publikováno v:
Neuro-Oncology. 15:1353-1365
CD44 is a molecular marker associated with cancer stem cell populations and treatment resistance in glioma. More effective therapies will result from approaches aimed at targeting glioma cells high in CD44.Glioma-initiating cell lines were derived fr
Autor:
Liangfu Zhou, Ying Mao, Aden Ka-Yin Chan, Kay Ka Wai Li, Zhifeng Shi, Wai Sang Poon, Ho Keung Ng, Yin Wang, Jesse Chung Sean Pang, Ling Yang, Kin-Mang Lau
Publikováno v:
Brain Pathology. 23:426-439
MicroRNA-137 (miR-137) expression has been reported to be decreased in astrocytic tumors in two expression profiling studies but its role in the pathogenesis of oligodendroglial tumors is still limited. In this study, we demonstrate that miR-137 expr
Autor:
Liangfu Zhou, Kin-Mang Lau, Ying Mao, Ho Keung Ng, Yin Wang, Jesse Chung Sean Pang, Kay Ka Wai Li, Wai Sang Poon
Publikováno v:
Brain Pathology. 23:413-425
Accumulating evidence suggests that microRNAs (miRNAs) are over- or under-expressed in tumors, and abnormalities in miRNA expression may contribute to carcinogenesis. MiR-383 was previously identified as one of the under-expressed miRNAs in medullobl
Autor:
Alfred S. L. Cheng, Kay K.W. Li, Queeny Kwan Yi Chan, Kin-Mang Lau, Liangfu Zhou, Ying Mao, Walter Wai Yeung, Nellie Yuk Fei Chung, Hiu Ming Li, Yin Wang, Hai Feng, Ho Keung Ng, Jesse Chung Sean Pang, Fanny Man Ting Ma
Publikováno v:
Acta Neuropathologica. 123:553-571
Overexpression of high mobility group AT-hook 1 (HMGA1) is common in human cancers. Little is known about the mechanisms underlying its deregulation and downstream targets, and information about its clinical and biological significance in medulloblas
Autor:
Kay Ka Wai Li, Kin-Mang Lau, Yiu-Loon Chui, Yin Mao, Nellie Yuk Fei Chung, Zhongping Chen, Wai Sang Poon, Liangfu Zhou, Yin Wang, John Wong, Danny Tat Ming Chan, Ho Keung Ng, Yeung Lam Ng, Vivian Wai Yan Lui, Jesse Chung Sean Pang, Hiu Ming Li
Publikováno v:
Brain Pathology. 20:1021-1032
Co-deletion of chromosomes lp and 19q is a common event in oligodendroglial tumors (OTs), suggesting the presence of OT-related genes. The aim of this study was to identify the target genes residing in the minimally deleted regions on chromosome 1p36
Publikováno v:
Cancer Genetics and Cytogenetics. 194:58-64
Nasopharyngeal carcinoma (NPC) is a unique type of head and neck cancer that is most prevalent in southern China. Previous studies have suggested that genetic susceptibility, environmental carcinogens, and Epstein–Barr virus (EBV) infection contrib
Autor:
Alfred S. L. Cheng, Weiqin Yang, Qiaoyi Liang, Jun Yu, Ka Fai To, Wei Kang, Yujuan Dong, Li Zhang, Jesse Chung Sean Pang, Junhong Zhao, Yi Pan, Raymond W.M. Lung, Joanna H.M. Tong
Publikováno v:
Molecular Cancer
Background MicroRNAs (miRNAs) have been reported to play an important role in tumorigenesis. In this study, the role of miR-15a and miR-16-1 in gastric adenocarcinoma (GAC) was investigated. Methods The expression of miR-15a and miR-16-1 in cell line