Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jesse B Owens"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Nonviral gene delivery systems are rapidly becoming a desirable and applicable method to overexpress genes in various types of cells. We have recently developed a piggyBac transposase-based, helper-independent and self-inactivating delivery system (p
Externí odkaz:
https://doaj.org/article/3e3580d876684d818bb428e1ddd92d15
Autor:
Timothy A Donlon, Brian J Morris, Kamal H Masaki, Randi Chen, Phillip M C Davy, Kalpana J Kallianpur, Kazuma Nakagawa, Jesse B Owens, D Craig Willcox, Richard C Allsopp, Bradley J Willcox
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 77(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a81c7a8db63b9610adeaf9e651d8e67
https://pubmed.ncbi.nlm.nih.gov/35960854
https://pubmed.ncbi.nlm.nih.gov/35960854
Publikováno v:
Synthetic Biology (Oxford, England)
Safer and more efficient methods for directing therapeutic genes to specific sequences could increase the repertoire of treatable conditions. Many current approaches act passively, first initiating a double-stranded break, then relying on host repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388afb7c71bb87b3b36dbf8cb9246dcd
https://doi.org/10.1093/synbio/ysz018
https://doi.org/10.1093/synbio/ysz018
Publikováno v:
Bioengineered. 7:3-6
The acceptance of bioengineered plants by some nations is hampered by a number of factors, including the random insertion of a transgene into the host genome. Emerging technologies, such as site-specific nucleases, are enabling plant scientists to pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc439348eae10eee3b18d34aa9a67370
https://doi.org/10.1080/21655979.2015.1131367
https://doi.org/10.1080/21655979.2015.1131367
Autor:
Olivier Le Saux, Carolin Bauer, Kevin Pham, Viola Pomozi, Ludovic Martin, Janna Zoll, Joel Marh, Christopher Brampton, Koen van de Wetering, Stefan Moisyadi, András Váradi, Zouhair Aherrahrou, Jeanette Erdmann, Jesse B. Owens, Bianca Calio
Publikováno v:
The American journal of pathology. 187(6)
Soft tissue calcification occurs in several common acquired pathologies, such as diabetes and hypercholesterolemia, or can result from genetic disorders. ABCC6, a transmembrane transporter primarily expressed in liver and kidneys, initiates a molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9a5bd4ff0fc6afe08a10b961a4e6d3
https://pubmed.ncbi.nlm.nih.gov/28416300
https://pubmed.ncbi.nlm.nih.gov/28416300
Autor:
Ilko Stoytchev, Mital S. Bhakta, David J. Segal, Damiano Mauro, Jesse B. Owens, Stefan Moisyadi, Moon-Soo Kim
Publikováno v:
Nucleic acids research, vol 41, iss 19
Nucleic Acids Research
Nucleic Acids Research
Insertional therapies have shown great potential for combating genetic disease and safer methods would undoubtedly broaden the variety of possible illness that can be treated. A major challenge that remains is reducing the risk of insertional mutagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549d7ad08cf3119910623aa97aeeec12
https://doi.org/10.1093/nar/gkt677
https://doi.org/10.1093/nar/gkt677
Autor:
Zoia Stoytcheva, Johann Urschitz, Kommineni J. Maragathavally, Jesse B. Owens, Stefan Moisyadi, Craig J. Coates, Mahdi Belcaid, David J. Segal, Nong C. Dang, Ilko Stoytchev
Publikováno v:
Nucleic acids research, vol 40, iss 14
Nucleic Acids Research
Nucleic Acids Research
Integrating vectors such as viruses and transposons insert transgenes semi-randomly and can potentially disrupt or deregulate genes. For these techniques to be of therapeutic value, a method for controlling the precise location of insertion is requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc8911058826ca802d30d154879b902
https://doi.org/10.1093/nar/gks309
https://doi.org/10.1093/nar/gks309
Autor:
Ryuzo Yanagimachi, Kris Kawamoto, Ilko Stoytchev, Hideaki Yamashiro, James A. Dee, Stefan Moisyadi, Joseph M. Kaminski, Joel Marh, Kazuto Morozumi, Johann Urschitz, Craig J. Coates, Pawel Pelczar, Jesse B. Owens, Miyuri Kawasumi
Publikováno v:
Proceedings of the National Academy of Sciences. 107:8117-8122
Efficient integration of functional genes is an essential prerequisite for successful gene delivery such as cell transfection, animal transgenesis, and gene therapy. Gene delivery strategies based on viral vectors are currently the most efficient. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d39430fd453b5a0c57fc8c148a0e325
https://doi.org/10.1073/pnas.1003674107
https://doi.org/10.1073/pnas.1003674107
Autor:
Chad B. Walton, Jesse B. Owens, Cynthia D. Anderson, Johann Urschitz, Ralph V. Shohet, Mark T. Khemmani, Stefan Moisyadi
Our aim was to evaluate the delivery of transposase-based vectors by ultrasound targeted microbubble destruction (UTMD) in mice. DNA vectors were attached to cationic lipid microbubbles (1–3 μm in diameter), injected intravenously and delivered to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110bbb9d0591b56af12150934c51c0c8
https://europepmc.org/articles/PMC3838570/
https://europepmc.org/articles/PMC3838570/
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Nonviral gene delivery systems are rapidly becoming a desirable and applicable method to overexpress genes in various types of cells. We have recently developed a piggyBac transposase-based, helper-independent and self-inactivating delivery system (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d0187b01709ece9dafc135cef88c3f