Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jesse A, Stokum"'
Autor:
J. Marc Simard, Bradley Wilhelmy, Natalya Tsymbalyuk, Bosung Shim, Jesse A. Stokum, Madison Evans, Anandita Gaur, Cigdem Tosun, Kaspar Keledjian, Prajwal Ciryam, Riccardo Serra, Volodymyr Gerzanich
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 229 (2024)
In human stroke, brain swelling is an important predictor of neurological outcome and mortality, yet treatments to reduce or prevent brain swelling are extremely limited, due in part to an inadequate understanding of mechanisms. In preclinical studie
Externí odkaz:
https://doaj.org/article/c88f3a70ab504422be2af4e18e61d667
Autor:
Bosung Shim, Jesse A. Stokum, Mitchell Moyer, Natalya Tsymbalyuk, Orest Tsymbalyuk, Kaspar Keledjian, Svetlana Ivanova, Cigdem Tosun, Volodymyr Gerzanich, J. Marc Simard
Publikováno v:
Cells, Vol 12, Iss 18, p 2221 (2023)
Brain swelling is a major cause of death and disability in ischemic stroke. Drugs of the gliflozin class, which target the Na+-coupled D-glucose cotransporter, SGLT2, are approved for type 2 diabetes mellitus (T2DM) and may be beneficial in other con
Externí odkaz:
https://doaj.org/article/a4ba6993b6224859895e1d4f7697e548
Autor:
Bizhan, Aarabi, Chen, Chixiang, J Marc, Simard, Timothy, Chryssikos, Jesse A, Stokum, Charles A, Sansur, Kenneth M, Crandall, Joshua, Olexa, Jeffrey, Oliver, Melissa R, Meister, Gregory, Cannarsa, Ashish, Sharma, Cara, Lomangino, Maureen, Scarboro, Abdul-Kareem, Ahmed, Nathan, Han, Riccardo, Serra, Phelan, Shea, Carla, Aresco, Gary T, Schwartzbauer
Publikováno v:
Journal of Neurotrauma. 39:1716-1726
Expansion duraplasty to reopen effaced subarachnoid space and improve spinal cord perfusion, autoregulation, and spinal pressure reactivity index (sPRX) has been advocated in patients with traumatic cervical spinal cord injury (tCSCI). We designed th
Autor:
Timothy Chryssikos, Jesse A. Stokum, Abdul-Kareem Ahmed, Chixiang Chen, Aaron Wessell, Gregory Cannarsa, Nicholas Caffes, Jeffrey Oliver, Joshua Olexa, Phelan Shea, Mohamed Labib, Graeme Woodworth, Alexander Ksendzovsky, Uttam Bodanapally, Kenneth Crandall, Charles Sansur, Gary Schwartzbauer, Bizhan Aarabi
Publikováno v:
Neurosurgery. 92:353-362
Autor:
Nina P. Connolly, Amol C. Shetty, Jesse A. Stokum, Ina Hoeschele, Marni B. Siegel, C. Ryan Miller, Anthony J. Kim, Cheng-Ying Ho, Eduardo Davila, J. Marc Simard, Scott E. Devine, John H. Rossmeisl, Eric C. Holland, Jeffrey A. Winkles, Graeme F. Woodworth
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Glioma is a unique neoplastic disease that develops exclusively in the central nervous system (CNS) and rarely metastasizes to other tissues. This feature strongly implicates the tumor-host CNS microenvironment in gliomagenesis and tumor pro
Externí odkaz:
https://doaj.org/article/f2d89c7796d7442691323a555b449266
Autor:
Volodymyr Gerzanich, Tapas K. Makar, Poornachander Reddy Guda, Min Seong Kwon, Jesse A. Stokum, Seung Kyoon Woo, Svetlana Ivanova, Alexander Ivanov, Rupal I. Mehta, Alexandra Brooke Morris, Joseph Bryan, Christopher T. Bever, J. Marc Simard
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-18 (2017)
Abstract Background In multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), inflammation is perpetuated by both infiltrating leukocytes and astrocytes. Recent work implicated SUR1-TRPM4 channels, expressed mostly by astrocytes
Externí odkaz:
https://doaj.org/article/ba716476bdc44f98aa780a2405bff6fe
Autor:
Kevin T, Kim, Aaron P, Wessell, Jeffrey, Oliver, Jason H, Boulter, Jesse A, Stokum, Cara, Lomangino, Maureen, Scarboro, Bizhan, Aarabi, Timothy, Chryssikos, Gary, Schwartzbauer
Publikováno v:
Neurosurgery. 90:708-716
Consensus is currently lacking in the optimal treatment for blunt traumatic cerebral venous sinus thrombosis (tCVST). Anticoagulation (AC) is used for treating spontaneous CVST, but its role in tCVST remains unclear.To investigate the characteristics
Autor:
Stephanie Cardona, Hammad Baqai, Fatima Mikdashi, Ayah Aligabi, Julianna Solomon, Hannah Frederick, Nahom Seyoum, Joshua Olexa, Jesse A. Stokum, Ashish Sharma, Melissa B. Pergakis, Quincy K. Tran
Publikováno v:
Neurocritical Care.
Autor:
Sana Iqbal, Erik G Hayman, Caron Hong, Jesse A Stokum, David B Kurland, Volodymyr Gerzanich, J Marc Simard
Publikováno v:
Brain Circulation, Vol 2, Iss 1, Pp 8-19 (2016)
Aneurysmal subarachnoid hemorrhage (SAH) typically carries a poor prognosis. Growing evidence indicates that overabundant production of nitric oxide (NO) may be responsible for a large part of the secondary injury that follows SAH. Although SAH modul
Externí odkaz:
https://doaj.org/article/8b62e0dd3077462ba5044b0a1b4e328a
Autor:
Gregory J. Cannarsa, Aaron P. Wessell, Timothy Chryssikos, Jesse A. Stokum, Kevin Kim, Helio De Paula Carvalho, Timothy R. Miller, Nicholas Morris, Neeraj Badjatia, Seemant Chaturvedi, Dheeraj Gandhi, J. Marc Simard, Gaurav Jindal
Publikováno v:
Neurosurgery. 90:66-71
Malignant cerebral edema (MCE) and intracranial hemorrhage (ICH) are associated with poor neurological outcomes despite revascularization after mechanical thrombectomy (MT). The factors associated with the development of MCE and ICH after MT are not