Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jessamy C, Tiffen"'
Autor:
Mehdi R. Pirozyan, Helen M. McGuire, Abdullah Al Emran, Hsin-Yi Tseng, Jessamy C. Tiffen, Jenny H. Lee, Matteo S. Carlino, Alexander M. Menzies, Georgina V. Long, Richard A. Scolyer, Barbara Fazekas de St Groth, Peter Hersey
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The development of changes in T cells, referred to as T cell exhaustion, has been suggested as a cause of primary or acquired resistance to immunotherapy by immune checkpoint blockade (ICB). A limited number of studies, largely performed on tumor inf
Externí odkaz:
https://doaj.org/article/6e68db4ea50f4cc7a1d2fb84e2013589
Autor:
Quintin Lee, Renhua Song, Dang Anh Vu Phan, Natalia Pinello, Jessica Tieng, Anni Su, James M. Halstead, Alex C. H. Wong, Michelle van Geldermalsen, Bob S.-L. Lee, Bowen Rong, Kristina M. Cook, Mark Larance, Renjing Liu, Fei Lan, Jessamy C. Tiffen, Justin J.-L. Wong
Publikováno v:
Cellular and Molecular Life Sciences. 80
Virilizer-like m6A methyltransferase-associated protein (VIRMA) maintains the stability of the m6A writer complex. Although VIRMA is critical for RNA m6A deposition, the impact of aberrant VIRMA expression in human diseases remains unclear. We show t
Autor:
Jinbiao Chen, Yang Zhao, Fan Zhang, Jia Li, Jade A. Boland, Ngan Ching Cheng, Ken Liu, Jessamy C. Tiffen, Patrick Bertolino, David G. Bowen, Andreas Krueger, Leszek Lisowski, Ian E. Alexander, Mathew A. Vadas, Emad El-Omar, Jennifer R. Gamble, Geoffrey W. McCaughan
Publikováno v:
Cellular and Molecular Life Sciences. 79
MiR-181 expression levels increased in hepatocellular carcinoma (HCC) compared to non-cancerous tissues. MiR-181 has been widely reported as a possible driver of tumourigenesis but also acts as a tumour suppressor. In addition, the miR-181 family reg
Autor:
Sara Alavi, Abdullah Al Emran, Hsin-Yi Tseng, Jessamy C. Tiffen, Helen Marie McGuire, Peter Hersey
Publikováno v:
Cancers; Volume 14; Issue 2; Pages: 323
Cancers, Vol 14, Iss 323, p 323 (2022)
Cancers
Cancers, Vol 14, Iss 323, p 323 (2022)
Cancers
Simple Summary T cells that undergo repeated stimulation undergo a change called T cell exhaustion (TEx) that limits their ability to kill cancer cells and infections with microorganisms. The factors involved in the initiation and kinetics of these c
Autor:
Quintin Lee, Renhua Song, Dang Anh Vu Phan, Natalia Pinello, Anni Su, Jessica Tieng, James M. Halstead, Alex CH Wong, Michelle van Geldermalsen, Bob S-L Lee, Bowen Rong, Kristina M. Cook, Mark Larance, Renjing Liu, Fei Lan, Justin Jong-Leong Wong, Jessamy C. Tiffen
Publikováno v:
SSRN Electronic Journal.
Autor:
Stuart J, Gallagher, Dilini, Gunatilake, Kimberley A, Beaumont, Danae M, Sharp, Jessamy C, Tiffen, Anja, Heinemann, Wolfgang, Weninger, Nikolas K, Haass, James S, Wilmott, Jason, Madore, Peter M, Ferguson, Helen, Rizos, Peter, Hersey
Publikováno v:
International journal of cancer. 142(9)
Mutations in BRAF activate oncogenic MAPK signalling in almost half of cutaneous melanomas. Inhibitors of BRAF (BRAFi) and its target MEK are widely used to treat melanoma patients with BRAF mutations but unfortunately acquired resistance occurs in t
Autor:
Qian, Wang, Kimberley A, Beaumont, Nicholas J, Otte, Josep, Font, Charles G, Bailey, Michelle, van Geldermalsen, Danae M, Sharp, Jessamy C, Tiffen, Renae M, Ryan, Mika, Jormakka, Nikolas K, Haass, John E J, Rasko, Jeff, Holst
Publikováno v:
International journal of cancer. 135(5)
Amino acids, especially leucine and glutamine, are important for tumor cell growth, survival and metabolism. A range of different transporters deliver each specific amino acid into cells, some of which are increased in cancer. These amino acids conse
The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells
Autor:
Jessamy C, Tiffen, Charles G, Bailey, Amy D, Marshall, Cynthia, Metierre, Yue, Feng, Qian, Wang, Sarah L, Watson, Jeff, Holst, John E J, Rasko
Publikováno v:
International journal of cancer. 133(7)
BORIS and CTCF are paralogous, multivalent 11-zinc finger transcription factors that play important roles in organizing higher-order chromatin architecture. BORIS is a cancer-testis antigen with a poorly defined function in cancer, although it has be