Differential Contributions of Specimen Types, Culturing, and 16S rRNA Sequencing in Diagnosis of Prosthetic Joint Infections

Autor: Jan Lorenzen, Mogens Brouw Jørgensen, Jeppe Lund Nilsen, Christian N. S. Pedersen, Per Halkjær Nielsen, Vesal Khalid, Jess Tvede Riis, Peter Lüttge Jordal, Magdalene Kubik, Lone Heimann Larsen, Ole Simonsen, Kaare Lehmann Nielsen, Sten Rasmussen, Trine Rolighed Thomsen, Yijuan Xu, Victor Vishwanath Iyer, Henrik Carl Schønheyder, Andreas Kappel, Majbritt Frost, Rune Vincents Fisker, Iben Ørsted, Mogens Berg Laursen, Poul Hedevang Christensen, Poul Torben Nielsen, Ramune Aleksyniene, Majbritt Hauge Kyneb, Henrik Christian Bertelsen, Lars Arendt Nielsen, Kristian Kjær Pedersen

Publikováno v: Journal of Clinical Microbiology
Larsen, L H, Khalid, V, Xu, Y, Thomsen, T R, Schønheyder, H C, The PRIS Study Group, Christensen, P H, Jørgensen, M B, Kappel, A, Laursen, M B, Nielsen, P T, Pedersen, C, Rasmussen, S, Riis, J T, Simonsen, O, Aleksyniene, R, Bertelsen, H C, Fisker, R V, Frost, M, Kubik, M, Iyer, V V, Ørsted, I, Nielsen, K L, Nielsen, J L, Nielsen, P H, Petersen, K K & Arendt-Nielsen, L 2018, ' Differential contributions of specimen types, culturing, and 16S rRNA sequencing in diagnosis of prosthetic joint infections ', Journal of Clinical Microbiology, vol. 56, no. 5, e01351-17, pp. 1-12 . https://doi.org/10.1128/JCM.01351-17

Prosthetic joint failure is mainly caused by infection, aseptic failure (AF), and mechanical problems. Infection detection has been improved with modified culture methods and molecular diagnostics. However, comparisons between modified and convention

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http://europepmc.org/articles/PMC5925708